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Lookup NU author(s): Dr Niamh Leonard,
Professor Archibald Malcolm,
Dr Clifford Lawrence,
Dr Michael Dahl
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The surgical management of recurrent or large squamous cell carcinoma (SCC) can be challenging as tumours often extend beyond visible margins. Micrographic surgery is a potentially effective method of ensuring complete clearance of tumour. A retrospective study of all cases of SCC treated by micrographic surgery in this department between 1986 and 1996 has been done. Sixty-one patients were treated using a formalin-fixed paraffin-embedded tissue technique with a median follow-up of 4 years, In two cases there was local recurrence and in three others metastasis to local Lymph nodes. The overall cure rate was 92% (56 of 61), which compares favourably with published series using chemosurgery and frozen tissue techniques. The results show that this technique of micrographic surgery is a satisfactory and cost-effective alternative to conventional frozen section techniques in the treatment of SCC. The formalin-fixed tissue method has the advantage of providing high-quality permanent histological sections using existing conventional pathology services.
Author(s): Turner RJ, Leonard N, Malcolm AJ, Lawrence CM, Dahl MGC
Publication type: Article
Publication status: Published
Journal: British Journal of Dermatology
ISSN (print): 0007-0963
ISSN (electronic): 1365-2133
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