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Persistent mydriasis following intravenous atropine in a neonate

Lookup NU author(s): Dr Idse Herrema


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A neonate whose mother had recently taken amitriptyline developed fixed dilated pupils after a modest dose of intravenous atropine. Interaction of atropine with neonatal amitriptyline levels is suggested and evidence of neonatal effects from maternal antidepressant use is examined. There were no neurological sequelae, and the neonate's pupils became reactive again after 7 h.

Publication metadata

Author(s): Yung M, Herrema I

Publication type: Article

Publication status: Published

Journal: Paediatric Anaesthesia

Year: 2000

Volume: 10

Issue: 4

Pages: 438-440

ISSN (print): 1155-5645

ISSN (electronic): 1460-9592

Publisher: Blackwell Science Ltd


DOI: 10.1046/j.1460-9592.2000.00561.x


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