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Bone marrow transplantation does not correct the hyper IgE syndrome

Lookup NU author(s): Professor Andrew GenneryORCiD, Dr Terence Flood, Dr Mario Abinun, Professor Andrew Cant


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Congenital immunodeficiency in hyper IgE syndrome is characterised by a markedly raised IgE level, recurrent staphylococcal skin infection and pneumatoceles. Standard treatments include anti-staphylococcal antibiotics. We report a severely affected patient in whom successful bone marrow transplantation was followed by reappearance of the immunodeficiency. We conclude that bone marrow transplantation does not cure the immunological features of the hyper IgE syndrome.

Publication metadata

Author(s): Gennery AR, Flood TJ, Abinun M, Cant AJ

Publication type: Article

Publication status: Published

Journal: Bone Marrow Transplantation

Year: 2000

Volume: 25

Issue: 12

Pages: 1303-1305

ISSN (print): 0268-3369

ISSN (electronic): 1476-5365

Publisher: Nature Publishing Group


DOI: 10.1038/sj.bmt.1702446


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