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Pulmonary edema in patients after liver transplantation

Lookup NU author(s): Dr Christopher Snowden, Dr John Rose

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Abstract

The aim of this study is to determine the incidence of radiological pulmonary edema in elective liver transplant recipients and its relationship to perioperative factors and postoperative course. Me reviewed 102 chest radiographs from 34 patients who had undergone orthotopic liver transplantation (OLT), Films were assessed by 2 trained radiologists for evidence of pulmonary edema using a standardized system. Clinical and outcome data from the 34 patients were also recorded. There was a high incidence (47%) of postoperative radiological pulmonary edema that was associated with deterioration in gaseous exchange, elevated pulmonary artery pressure, and increased duration of ventilator dependence and intensive care stay. Eighteen percent of the patients developed edema immediately after surgery, which was associated with greater pulmonary artery pressure and transfusion requirements during surgery, An additional 29% developed edema during the next 16 to 20 hours, but there was no association with fluid replacement. We conclude that pulmonary edema is common after OLT and will influence postoperative recovery in a substantial proportion of transplant recipients. Excess perioperative fluid replacement is unlikely to be the sole mechanism of edema in these patients.


Publication metadata

Author(s): Snowden CP, Hughes T, Rose J, Roberts DRD

Publication type: Article

Publication status: Published

Journal: Liver Transplantation

Year: 2000

Volume: 6

Issue: 4

Pages: 466-470

ISSN (print): 1527-6465

ISSN (electronic): 1527-6473

Publisher: John Wiley & Sons

URL: http://dx.doi.org/10.1053/jlts.2000.7580

DOI: 10.1053/jlts.2000.7580


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