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Lookup NU author(s): Emeritus Professor Bernard Golding
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As a key starting material in synthesis of HIV-RT inhibitors, Ethyl 3-oxo-(S)-(+)-6,7-di-O-isopropylidene-6,7-dihydroxyheptanoate (1) was synthesized from (S)-(+)-glutamic acid and Meldrum's acid (7) through six steps of reactions. The structures of all compounds were characterized by elemental analysis, IR, H-1 MMR, C-13 NMR and MS.
Author(s): Liu JY, Ma XY, Golding BT
Publication type: Article
Publication status: Published
Journal: Chinese Journal of Inorganic Chemistry
ISSN (print): 0253-2786
Publisher: Kexue Chubanshe