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Lookup NU author(s): Emerita Professor Janet WilsonORCiD
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The purpose of this study was to determine whether mucin expression is altered in laryngeal cancer. MUC1 and MUC2 mucin expression was examined in biopsy specimens from 80 patients that comprised 23 laryngeal dysplasias, 36 laryngeal carcinomas, and 21 normal larynx control specimens. High MUC1 expression was found in all 3 groups (P = 0.689, Fisher exact test). However, significantly higher levels of MUC2 expression were detected in carcinomas compared with dysplasias and control specimens (P = 0.009, Fisher exact test). Altered MUGS expression may be an important step in carcinogenesis in laryngeal cancer.
Author(s): Jeannon, J.P., Stafford, F.W., Soames, J.V., Wilson, J.A.
Publication type: Article
Publication status: Unknown
Journal: Otolaryngology - Head and Neck Surgery
ISSN (print): 0194-5998
ISSN (electronic): 1097-6817
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