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Haemodialysing infants: theoretical limitations, and single versus double lumen lines

Lookup NU author(s): Dr Malcolm Coulthard


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Haemodialysing small infants is difficult because of vascular access limitations. We show that Poiseuille's law (that now through a tube varies with its radius(4)) makes it inevitable that the blood flow that can be achieved in smaller patients will fall disproportionately compared to their need for dialysis. Poiseuille's law also predicts that for single and multiple lumen cannulae of the same outside gauge, blood flow through the single lu men will be several times greater. Measurements confirmed this. It is argued that haemodialysis efficiency will therefore be improved by using a single lumen cannula to alternately withdraw and return blood, compared to sampling and returning continuously through a multiple lumen cannula, despite only withdrawing for half the time.

Publication metadata

Author(s): Coulthard MG, Sharp J

Publication type: Article

Publication status: Published

Journal: Pediatric Nephrology

Year: 2001

Volume: 16

Issue: 4

Pages: 332-334

ISSN (print): 0931-041X

ISSN (electronic): 1432-198X

Publisher: Springer


DOI: 10.1007/s004670000547

PubMed id: 11354776


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