Browse by author
Lookup NU author(s): Professor Patrick Chinnery,
Emeritus Professor Doug Turnbull
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
The last ten years have seen a huge increase in the number of different genetic defects found in patients with mitochondrial disorders, but the true impact of mitochondrial disease is only just becoming apparent. Mitochondrial diseases are far more common than was anticipated. Although there have also been major advances in our understanding of mitochondrial pathology, the clinical management of patients with mitochondrial disease is largely supportive. In this article, we focus on primary disorders of the mitochondrial respiratory chain and mtDNA defects. We review the available epidemiological data, outline current strategies for the management of mitochondrial disease, and highlight new therapeutic approaches that may prove useful in the future, (C) 2001 Wiley-Liss, Inc.
Author(s): Chinnery PF, Turnbull DM
Publication type: Article
Publication status: Published
Journal: American Journal of Medical Genetics
ISSN (print): 1552-4825
ISSN (electronic): 1552-4833
Publisher: John Wiley & Sons, Inc.
Altmetrics provided by Altmetric