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Endoscopic versus open surgical interventions for inverted nasal papilloma: a systematic review

Lookup NU author(s): Dr Petros Karkos, Sean Carrie


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Inverted nasal papilloma is a unique neoplasm characterised by a tendency to recur following excision, an association with malignancy and an ability to destroy bone. The coexistence with nasal polyps (not always sent for histology), the lack of a universally accepted staging system and the fact that most data on Inverted papilloma come from tertiary centres (selected cases probably the most aggressive) account for the difficulty in determining its true incidence. Treatment is surgical. The gold standard approach was an open radical procedure. The introduction of endoscopic surgery for primary or recurrent lesions has shown potential advantages. Lack of complications of open surgery together with improved access to specific nasal areas suggests that the endoscopic techniques in experienced hands and for selected lesions may be a good alternative. The aim of this review was to assess the effectiveness of the endoscopic versus open techniques for management of inverted papilloma. There is not enough evidence in the literature to support one or the other treatment option for management of inverted papilloma. There is a trend though towards endoscopic approach. Ideal management should aim at complete removal of all diseased mucosa with creation of wide cavities and long term follow-up to detect subsequent recurrence or malignant transformation.

Publication metadata

Author(s): Karkos PD, Fyrmpas G, Carrie SC, Swift AC

Publication type: Review

Publication status: Published

Journal: Clinical Otolaryngology

Year: 2006

Volume: 31

Issue: 6

Pages: 499-503

ISSN (print): 1749-4478

ISSN (electronic): 1749-4486


DOI: 10.1111/j.1365-2273.2006.01333.x