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Localized reactive angioendotheliomatosis

Lookup NU author(s): Dr Brian Angus, Dr Patrick Kesteven


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We present a unique case of a woman with multiple painful dermal lesions localized to the left upper quadrant of the body. Histological investigation revealed microvascular thrombosis with capillary-wall proliferation. Further investigation revealed a very high anticardiolipin IgG titre and a left subclavian stenosis, presumably providing the reduced blood flow and relative hypoxia to allow microthromboses to occur in the presence of a thrombophilic tendency. Similar clinical and histological features have been reported in patients with the antiphospholipid syndrome and cases of reactive angioendotheliomatosis (RAE). This case represents a unique variant of RAE.

Publication metadata

Author(s): Kirke S, Angus B, Kesteven PJL, Calonje E, Simpson N

Publication type: Article

Publication status: Published

Journal: Clinical and Experimental Dermatology

Year: 2007

Volume: 32

Issue: 1

Pages: 45-47

ISSN (print): 0307-6938

ISSN (electronic): 1365-2230

Publisher: Wiley-Blackwell


DOI: 10.1111/j.1365-2230.2006.02254.x


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