Dr Marzena Kurzawa-Akanbi Nik Tzoumas Professor David Steel Professor Lyle Armstrong Professor Majlinda Lako et al. | Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity | 2024 |
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Rob Atkinson Dr Maria Georgiou Dr Chunbo Yang Marina Moya Molina Dr Joseph Collin et al. | PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects | 2024 |
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Dr Rozaliya Tsikandelova Eldo Galo Edvinas Cerniauskas Dr Dean Hallam Dr Maria Georgiou et al. | Retinal cells derived from patients with DRAM2-dependent CORD21 dystrophy exhibit key lysosomal enzyme deficiency and lysosomal content accumulation | 2024 |
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Dr Marzena Kurzawa-Akanbi Dr Florence Burte Dr Birthe Hilgen Dr Rachel Queen Dr Jonathan Coxhead et al. | Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina | 2022 |
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Dr Marzena Kurzawa-Akanbi Professor David Steel Professor Majlinda Lako
| Age-related macular degeneration - Biomarkers and therapies | 2021 |
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Dr Marzena Kurzawa-Akanbi Rachel Heap Professor Matthias Trost Dr Preeti Singh Dr Florence Burte et al. | Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body disorders | 2021 |
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Dr Marzena Kurzawa-Akanbi Dr Michael Keogh Eliona Tsefou Lynne Ramsay Mary Johnson et al. | Neuropathological and Biochemical Investigation of Hereditary Ferritinopathycases with Ferritin Light Chain Mutation: Prominent Protein Aggregation in the Absence of Major Mitochondrial or Oxidative Stress | 2021 |
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Edvinas Cerniauskas Dr Marzena Kurzawa-Akanbi Dr Long Xie Dr Dean Hallam Marina Moya Molina et al. | Complement modulation reverses pathology in Y402H-retinal pigment epithelium cell model of AMD by restoring lysosomal function | 2020 |
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Dr Hannah Lowes Dr Marzena Kurzawa-Akanbi Dr Angela Pyle Professor Gavin Hudson
| Post-mortem ventricular cerebrospinal fluid cell-free-mtDNA in neurodegenerative disease | 2020 |
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Professor Tiago Outeiro Dr David Koss Dr Daniel Erskine Dr Lauren Walker Dr Marzena Kurzawa-Akanbi et al. | Dementia with Lewy bodies: an update and outlook | 2019 |
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Dr Sai Kolli Dr Sanja Bojic Dr Ali Ghareeb Dr Marzena Kurzawa-Akanbi Professor Francisco Figueiredo et al. | The Role of Nerve Growth Factor in Maintaining Proliferative Capacity, Colony‐Forming Efficiency, and the Limbal Stem Cell Phenotype | 2019 |
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Dr Marzena Kurzawa-Akanbi Professor Patrick Chinnery
| Stem cell modeling of mitochondrial parkinsonism reveals key functions of OPA1 | 2018 |
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Dr Michael Keogh Dr Wei Wei Dr Ian Wilson Dr Jonathan Coxhead Dr Helen Griffin et al. | Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource | 2017 |
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Dr Michael Keogh Dr Ian Wilson Dr Jonathan Coxhead Dr Helen Griffin Dr Marzena Kurzawa-Akanbi et al. | Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains | 2017 |
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Dr Michael Keogh Dr Marzena Kurzawa-Akanbi Dr Helen Griffin Dr Konstantinos Douroudis Dr Kristin Ayers et al. | Exome sequencing in dementia with Lewy bodies | 2016 |
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Dr Angela Pyle Haidyan Anugrha Dr Marzena Kurzawa-Akanbi Professor Alison Yarnall Professor David Burn et al. | Reduced mitochondrial DNA copy number is a biomarker of Parkinson's disease | 2016 |
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Dr Angela Pyle Hannah Lowes Rebecca Brennan Dr Marzena Kurzawa-Akanbi Professor Alison Yarnall et al. | Reduced Mitochondrial DNA Is Not a Biomarker of Depression in Parkinson's Disease | 2016 |
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Dr Jonathan Coxhead Dr Marzena Kurzawa-Akanbi Raf Hussain Dr Angela Pyle Professor Patrick Chinnery et al. | Somatic mtDNA variation is an important component of Parkinson's disease | 2016 |
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Professor Grainne Gorman Dr Gerald Pfeffer Dr Helen Griffin Dr Marzena Kurzawa-Akanbi Jessica Gabriel et al. | Clonal Expansion of Secondary Mitochondrial DNA Deletions Associated With Spinocerebellar Ataxia Type 28 | 2015 |
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Dr Angela Pyle Rebecca Brennan Dr Marzena Kurzawa-Akanbi Professor Alison Yarnall Anais Thouin et al. | Reduced CSF mitochondrial DNA is a biomarker for early-stage Parkinson's disease | 2015 |
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Dr Marzena Kurzawa-Akanbi Professor Patrick Chinnery Dr Christopher Morris
| Selective loss of glucocerebrosidase activity in sporadic Parkinson's disease and dementia with Lewy bodies | 2015 |
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Dr Gerald Pfeffer Professor Grainne Gorman Dr Helen Griffin Dr Marzena Kurzawa-Akanbi Dr Ian Wilson et al. | Mutations in the SPG7 gene cause chronic progressive external ophthalmoplegia through disordered mitochondrial DNA maintenance | 2014 |
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Dr Marzena Kurzawa-Akanbi Professor Ian McKeith Professor Patrick Chinnery Dr Christopher Morris Emeritus Professor John Harris et al. | A Multicenter Study of Glucocerebrosidase Mutations in Dementia With Lewy Bodies | 2013 |
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Dr Marzena Kurzawa-Akanbi Dr Peter Hanson Professor Peter Blain Debbie Lett Professor Ian McKeith et al. | Glucocerebrosidase Mutations alter the endoplasmic reticulum and lysosomes in Lewy body disease | 2012 |
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Paul Keane Dr Marzena Kurzawa-Akanbi Professor Peter Blain Dr Christopher Morris
| Mitochondrial dysfunction in Parkinson's Disease | 2011 |
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Dr Kasia Tonska Dr Marzena Kurzawa-Akanbi
| A family with 3460G>A and 11778G>A mutations and haplogroup analysis of Polish Leber hereditary optic neuropathy patients | 2008 |
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