Publications by Professor Muzlifah Haniffa - ePrints

Browsing publications by Professor Muzlifah Haniffa.

Newcastle Authors	Title	Year
Issac Goh Dr Laura Jardine Dr Rachel Botting Emily Stephenson Justin Engelbert et al.	IMMUNOLOGY Mapping the developing human immune system across organs	2022
Professor Muzlifah Haniffa	Single-cell transcriptomics links malignant T cells to the tumor immune landscape in cutaneous T cell lymphoma	2022
Dr Laura Jardine Dr Simone Webb Justin Engelbert Dr Owen Williams Professor Olaf Heidenreich et al.	Single-cell transcriptomics reveals a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia	2022
Professor Muzlifah Haniffa Dr Bayanne Olabi Dr Roser Vento-Tormo Dr Simone Webb	A Roadmap for the Human Developmental Cell Atlas	2021
Dr Laura Jardine Dr Simone Webb Issac Goh Dr Gary Reynolds Dr Michael Mather et al.	Blood and immune development in human fetal bone marrow and Down syndrome	2021
Issac Goh Kai'En Dr Steven Lisgo Emily Stephenson Justin Engelbert Dr Rachel Botting et al.	Cells of the human intestinal tract mapped across space and time	2021
Dr Michael Mather Dr Laura Jardine Dr Ben Talks Dr Louis Gardner Professor Muzlifah Haniffa et al.	Complexity of immune responses in COVID-19	2021
Catherine Hatton Dr Rachel Botting Dr Maria Duenas Fadic Dr Iram Haq Dr Bernard Verdon et al.	Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2	2021
Dr Michael Mather Dr Bernard Verdon Dr Rachel Botting Justin Engelbert Livia Delpiano et al.	Development of a physiological model of human middle ear epithelium	2021
Dr Gary Reynolds Dr Peter Vegh Dr James Fletcher Dr Beth Poyner Emily Stephenson et al.	Developmental cell programs are co-opted in inflammatory skin disease	2021
Dr Michael Mather Steven Powell Dr Ben Talks Professor Christopher Ward Professor Muzlifah Haniffa et al.	Dysregulation of immune response in otitis media	2021
Dr Gary Reynolds Emily Stephenson Dr Louis Gardner Professor Muzlifah Haniffa	Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19	2021
Dr Rachel Botting Dr Peter Vegh Dr James Fletcher Professor Muzlifah Haniffa	Human anogenital monocyte-derived dendritic cells and langerin+cDC2 are major HIV target cells	2021
Dr Rebecca Payne Alex Nicols Jess Tyerman Dr Tom Altmann Dr Christopher Duncan et al.	Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine	2021
Dr Gary Reynolds Professor Muzlifah Haniffa	Local and systemic responses to SARS-CoV-2 infection in children and adults	2021
Professor Muzlifah Haniffa	Single cell derived mRNA signals across human kidney tumors	2021
Emily Stephenson Dr Gary Reynolds Dr Rachel Botting Justin Engelbert Dr Bayanne Olabi et al.	Single-cell multi-omics analysis of the immune response in COVID-19	2021
Professor Muzlifah Haniffa	Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell	2021
Dr Rachel Botting Dr Cecilia Dominguez Conde Dr Dorin-Mirel Popescu Emily Stephenson Dr Simone Webb et al.	A cell atlas of human thymic development defines T cell repertoire formation	2020
Dr Laura Jardine Dr Urszula Cytlak-Chaudhuri Dr Merry Gunawan Dr Gary Reynolds Dr Kile Green et al.	Donor monocyte-derived macrophages promote human acute graft-versus-host disease	2020
Dr Gary Reynolds Professor Muzlifah Haniffa	Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation	2020
Professor Muzlifah Haniffa	SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues	2020
Professor Muzlifah Haniffa	Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth	2020
Dr Rachel Botting Professor Muzlifah Haniffa	The developing immune network in human prenatal skin	2020
Dr Beth Poyner Dr Anna Dubois Professor Muzlifah Haniffa	Are regulatory T cells associated with cutaneous viral infections?	2019
Dr Dorin-Mirel Popescu Dr Rachel Botting Emily Stephenson Dr Kile Green Dr Simone Webb et al.	Decoding human fetal liver haematopoiesis	2019
Dr Rachel Botting James Fletcher Professor Muzlifah Haniffa	Identification of HIV transmitting CD11c+ human epidermal dendritic cells	2019
Dr Laura Jardine Dr Sarah Wiscombe Dr Gary Reynolds Dr David McDonald Andrew Fuller et al.	Lipopolysaccharide inhalation recruits monocytes and dendritic cell subsets to the alveolar airspace.	2019
Dr Matthew Wood Adam Leckenby Dr Gary Reynolds Dr Rachel Spiering Dr Arthur Pratt et al.	Macrophage proliferation distinguishes 2 subgroups of knee osteoarthritis patients	2019
Dr Rachel Botting Dr Dorin-Mirel Popescu Dr Roser Vento-Tormo Emily Stephenson Dr Kile Green et al.	Spatiotemporal immune zonation of the human kidney	2019
Dr Kile Green Katie Best Professor Muzlifah Haniffa	Epithelial damage and tissue γδ T cells promote a unique tumor-protective IgE response	2018
James Fletcher Emily Stephenson Dr Peter Vegh Professor Muzlifah Haniffa	Gene expression variability across cells and species shapes innate immunity.	2018
Dr Rachel Botting Emily Stephenson Dr Ben Barron-Millar Barbara Innes Dr Rebecca Payne et al.	Single-cell reconstruction of the early maternal–fetal interface in humans	2018
Emily Stephenson Dr Andrew Filby Dr Steven Lisgo Emerita Professor Susan Lindsay Professor Muzlifah Haniffa et al.	Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors	2018
Dr Peter Vegh Professor Muzlifah Haniffa	The impact of single-cell RNA sequencing on understanding the functional organization of the immune system	2018
Dr Paul Milne Dr Venetia Bigley Dr Christopher Bacon Dr Naomi McGovern Dr Simon Bomken et al.	Hematopoietic origin of Langerhans cell histiocytosis and Erdheim Chester disease in adults	2017
Dr Naomi McGovern Dr Xiao Wang Dr Venetia Bigley Professor Matthew Collin Professor Muzlifah Haniffa et al.	Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2	2017
Dr Merry Gunawan Professor Muzlifah Haniffa	Mapping the human DC lineage through the integration of high-dimensional techniques	2017
James Fletcher Professor Muzlifah Haniffa	Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes	2017
Dr Gary Reynolds James Fletcher Dr Laura Jardine David Dixon Emily Stephenson et al.	Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors	2017
Professor Muzlifah Haniffa	Comparative genomics analysis of mononuclear phagocyte subsets confirms homology between lymphoid tissue-resident and dermal XCR1⁺DCs in mouse and human and distinguishes them from Langerhans cells	2016
Katie Best Dr Merry Gunawan Professor Muzlifah Haniffa	Cross-priming of the melanoma antigen, Melan-A, by human dendritic cells	2016
Professor Matthew Collin Professor Muzlifah Haniffa	Dendritic Cells and Dendritic Cell Subsets	2016
Kile Green Dr Laura Jopson Dr Ben Barron-Millar Barbara Innes Sarah Pagan et al.	Early Molecular Stratification of High-risk Primary Biliary Cholangitis	2016
Dr Merry Gunawan Professor Muzlifah Haniffa	Identification of human DC precursors through the integration of high dimensional strategies	2016
Professor Philip Sloan Professor Muzlifah Haniffa	Rosai-Dorfman disease: successful treatment with methotrexate	2016
Dr Gary Reynolds Dr Arthur Pratt Dr David Coady Dr Graham Raftery Dr Alice Lorenzi et al.	Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis	2016
Professor Matthew Collin Dr Paul Milne Dr Venetia Bigley Professor Muzlifah Haniffa	The Hematopoietic Origin of Adult Histiocytosis	2016
Dr Gary Reynolds Dr Paul Milne Dr Venetia Bigley Professor Matthew Collin Professor John Isaacs et al.	Use of the dendritic cell marker, B and T lymphocyte attenuator, to identify functionally distinct subsets of human CD1c+ dendritic cells	2016
Dr Paul Milne Dr Venetia Bigley Dr Merry Gunawan Professor Muzlifah Haniffa Professor Matthew Collin et al.	CD1c⁺ blood dendritic cells have Langerhans cell potential	2015
Dr Gary Reynolds Professor Muzlifah Haniffa	Human and mouse mononuclear phagocyte networks: a tale of two species?	2015
Professor Muzlifah Haniffa Dr Venetia Bigley Professor Matthew Collin	Human mononuclear phagocyte system reunited	2015
Professor Muzlifah Haniffa Dr Merry Gunawan Dr Laura Jardine	Human skin dendritic cells in health and disease	2015
Dr Venetia Bigley Dr Naomi McGovern Dr Paul Milne Dr Rachel Dickinson Sarah Pagan et al.	Langerin-expressing dendritic cells in human tissues are related to CD1c⁺ dendritic cells and distinct from Langerhans cells and CD₁₄₁^high XCR1⁺ dendritic cells	2015
Dr Paul Milne Professor Matthew Collin Dr Venetia Bigley Dr Christopher Bacon Dr Naomi McGovern et al.	Mapping the BRAFV600E Hematopoietic Clone of Adult Multi-System Langerhans Cell Histiocytosis	2015
Professor Muzlifah Haniffa	Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells	2015
Professor Matthew Collin Dr Paul Milne Dr Venetia Bigley Professor Muzlifah Haniffa	Studies on the Pathway of Differentiation of LCH Cells	2015
Dr Xiao Wang Dr Naomi McGovern Dr Merry Gunawan Dr Connor Richardson Professor Matthew Collin et al.	A Three Dimensional Atlas of Human Dermal Leukocytes, Lymphatics and Blood Vessels	2014
Professor Muzlifah Haniffa	Arginase-dependent metabolic regulation of hepatic immunopathology by myeloid-derived suppressor cells	2014
Dr Paul Milne Dr Venetia Bigley Dr Merry Gunawan Professor Muzlifah Haniffa Professor Matthew Collin et al.	CD1c+ blood dendritic cells have Langerhans cell potential	2014
Dr Xiao Wang Dr Christopher Bacon Alison Long Sarah Pagan Professor Matthew Collin et al.	Factor XIIIa identifies macrophages and cells of mesenchymal origin in the human skin	2014
Dr Venetia Bigley Professor Muzlifah Haniffa Professor Sophie Hambleton	Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8^K108E mutation	2014
Dr Naomi McGovern Dr Merry Gunawan Dr Laura Jardine Dr Elizabeth Poyner Kile Green et al.	Human Dermal CD14⁺ Cells Are a Transient Population of Monocyte-Derived Macrophages	2014
Dr Venetia Bigley Dr Rachel Dickinson Dr Laura Jardine Dr Paul Milne Dr Helen Griffin et al.	Human SHP-1 Mutation Causes an Autoinflammatory and Immunodeficiency Phenotype	2014
Dr Naomi McGovern Dr Merry Gunawan Dr Laura Jardine Dr Elizabeth Poyner Dr Kile Green et al.	Human tissue mononuclear phagocyte system revisited	2014
Dr Xiao Wang Dr Naomi McGovern Dr Merry Gunawan Dr Connor Richardson Professor Matthew Collin et al.	Microanatomical dissection of the human dermis: the three-dimensional relationship between leucocytes, lymphatics and blood vessels	2014
Professor Muzlifah Haniffa	Selective Susceptibility of Human Skin Antigen Presenting Cells to Productive Dengue Virus Infection	2014
Dr Rachel Dickinson Paul Milne Dr Laura Jardine Dr Naomi McGovern Dr Sharon Cookson et al.	The evolution of cellular deficiency in GATA2 mutation	2014
Professor Matthew Collin Dr Naomi McGovern Professor Muzlifah Haniffa	Human dendritic cell subsets	2013
Dr Naomi McGovern Dr Laura Jardine Harriet Purvis Professor Catharien Hilkens Professor Matthew Collin et al.	IRF4 Transcription Factor-Dependent CD11b⁺ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses	2013
Dr Naomi McGovern Dr Kevin Windebank Sarah Pagan Dr Venetia Bigley Professor Matthew Collin et al.	Microanatomical dissection of the human dermis: The relationship between antigen presenting cells, lymphatic and blood vessels	2013
Dr Laura Jardine Ashley Ames-Draycott Sarah Pagan Dr Sharon Cookson Dr Gavin Spickett et al.	Rapid detection of dendritic cell and monocyte disorders using CD4 as a lineage marker of the human peripheral blood antigen-presenting cell compartment	2013
Dr Kevin Windebank Dr Venetia Bigley Professor Muzlifah Haniffa Professor Matthew Collin	Treatment of Adult LCH with Subcutaneous Cladribine	2013
Dr Stamatina Verykiou Dr Naomi McGovern Paul Milne Professor Matthew Collin Professor Muzlifah Haniffa et al.	Enhancing diagnostic sensitivity for cutaneous blastic plasmacytoid dendritic cell neoplasia	2012
Professor Matthew Collin Dr Rachel Dickinson Professor Muzlifah Haniffa Dr Naomi McGovern Dr Helen Griffin et al.	Evolution of Dendritic Cell, Monocyte B and NK Lymphoid (DCML) deficiency; a human primary immunodeficiency arising from GATA-2 mutation	2012
Dr Venetia Bigley Dr Rachel Dickinson Professor Andrew Gennery Dr Helen Griffin Professor Muzlifah Haniffa et al.	Human dendritic cell deficiency	2012
Professor Muzlifah Haniffa Dr Venetia Bigley Dr Naomi McGovern Dr Xiao Wang Sarah Pagan et al.	Human Tissues Contain CD141^hiCross-Presenting Dendritic Cells with Functional Homology to Mouse CD103⁺ Nonlymphoid Dendritic Cells	2012
Professor Muzlifah Haniffa Dr Venetia Bigley Dr Naomi McGovern Dr Xiao Wang Professor Matthew Collin et al.	Identification of a novel cross-presenting migratory dendritic cell in the human skin: the key cell for rational vaccine strategies	2012
Professor Muzlifah Haniffa Dr Venetia Bigley Dr Naomi McGovern Dr Xiao Wang Professor Matthew Collin et al.	Identification of the human cross-presenting migratory dendritic cell	2012
Professor Muzlifah Haniffa Dr Venetia Bigley Dr Naomi McGovern Professor Matthew Collin	Identification of the human cross-presenting migratory dendritic cell and harmonization of the functional classification of human and mouse dendritic cells	2012
Dr Katherine Sturgess Dr Mary Slatter Dr Venetia Bigley Dr Rachel Dickinson Professor Muzlifah Haniffa et al.	Reduced-intensity haematopoietic stem cell transplant rescues immune function and corrects pulmonary alveolar proteinosis in DCML deficiency/GATA 2 mutation	2012
Professor Sophie Hambleton Dr Venetia Bigley Professor Muzlifah Haniffa Dr Christopher Bacon Professor Andrew Cant et al.	IRF8 Mutations and Human Dendritic-Cell Immunodeficiency	2011
Professor Muzlifah Haniffa Dr Venetia Bigley Dr Naomi McGovern Dr Xiao Wang Hongwei Zhou et al.	CD141(+) human migratory dendritic cells are homologous to murine CD103+dendritic cells and excel at exogenous antigen cross-presentation	2011
Dr Venetia Bigley Professor Muzlifah Haniffa Dr Xiao Wang Dr Rachel Dickinson Dr Naomi McGovern et al.	Dendritic cell, monocyte, B and NK lymphoid deficiency: a novel but potentially fatal haematological disorder curable with haematopoietic stem cell transplantation	2011
Dr Rachel Dickinson Dr Helen Griffin Dr Venetia Bigley Dr Louise Reynard Raf Hussain et al.	Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency	2011
Professor Matthew Collin Dr Venetia Bigley Professor Muzlifah Haniffa Professor Sophie Hambleton	Human dendritic cell deficiency: the missing ID?	2011
Dr Naomi McGovern Dr Venetia Bigley Professor Muzlifah Haniffa Dr Xiao Wang Dr Rachel Dickinson et al.	Human Langerin plus dendritic cells are independent of epithelial Langerhans cells; a novel perspective on Langerhans cell histiocytosis	2011
Dr Katherine Sturgess Dr Mary Slatter Dr Venetia Bigley Professor Muzlifah Haniffa Dr Xiao Wang et al.	Reduced Intensity Hematopoietic Stem Cell Transplant Rescues Immune Function and Corrects Pulmonary Alveolar Proteinosis in DCML Deficiency/GATA 2 Mutation	2011
Professor Muzlifah Haniffa Professor Matthew Collin	Comparison of gene expression profiles between human and mouse monocyte subsets	2010
Professor Muzlifah Haniffa Professor Matthew Collin	Comparison of gene expression profiles between human and mouse monocyte subsets (Blood (2010) 115, 3 (e10-e19))	2010
Professor Muzlifah Haniffa Dr Venetia Bigley Sarah Pagan Dr Xiao Wang Professor Matthew Collin et al.	The persistence of recipient antigen presenting cells after stem cell transplantation in humans	2010
Professor Muzlifah Haniffa Dr Xiao Wang Dr Venetia Bigley Ian Dimmick Dr Trevor Booth et al.	Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation	2009
Professor Matthew Collin Dr Venetia Bigley Professor Muzlifah Haniffa Dr Kevin Windebank	Langerin Plus Dermal Dendritic Cells: Closer to Langerhans Cell Histiocytosis than Langerhans Cells?	2009
Professor Muzlifah Haniffa Professor Matthew Collin	Mesenchymal stem cells: The fibroblasts' new clothes?	2009
Dr Amy Anderson Bethan Sayers Professor Muzlifah Haniffa Dr David Swan Julie Diboll et al.	Differential regulation of naïve and memory CD4+ T cells by alternatively activated dendritic cells	2008
Professor Muzlifah Haniffa Suzanne Alshemali Professor Matthew Collin	Human factor XIIIa+ melanophages outlive all other cutaneous antigen-presenting cells, including Langerhans cells, after haematopoietic transplantation	2008
Dr Xiao Wang Professor Muzlifah Haniffa Dr Udo Holtick Professor Catharien Hilkens Professor Anne Dickinson et al.	Naturally occurring regulatory T-cells suppress CD8+lymphocyte induced graft-versus-host reactions in an in vitro human GvHD model	2008
Dr Karen Wallace Professor Muzlifah Haniffa Professor Matthew Collin Professor Matthew Wright	Skin Derived Fibroblasts Can Differentiate Into Hepatocyte-Like Cells	2008
Professor Muzlifah Haniffa Dr Xiao Wang Dr Udo Holtick Dr Michelle Rae Professor John Isaacs et al.	Adult Human Fibroblasts Are Potent Immunoregulatory Cells and Functionally Equivalent to Mesenchymal Stem Cells	2007
Bethan Sayers Professor Muzlifah Haniffa Julie Diboll Professor John Isaacs Professor Catharien Hilkens et al.	Generation of dexamethasone and vitamin D3-treated human monocyte-derived dendritic cells with tolerogenic properties	2007
Dr Sophie Weatherhead Professor Muzlifah Haniffa Dr Clifford Lawrence	Melanomas arising from naevi and de novo melanomas - does origin matter?	2007
Professor Muzlifah Haniffa Dr Xiao Wang Dr Udo Holtick Dr Daniel Swan Professor Anne Dickinson et al.	Mesenchymal stem cells and fibroblasts have similar immunoregulatory properties in vitro but distinct gene expression profiles: Implications for cellular therapy	2007
Professor Muzlifah Haniffa Dr James Lloyd Dr Clifford Lawrence	The use of a spectrophotometric intracutaneous analysis device in the real-time diagnosis of melanoma in the setting of a melanoma screening clinic	2007
Professor Muzlifah Haniffa Dr Bridget Wilkins Dr Nicholas Simpson	Cutaneous extramedullary hemopoiesis in chronic myeloproliferative and myelodysplastic disorders	2006
Suzanne Alshemali Dr Xiao Wang Professor Catharien Hilkens Professor Muzlifah Haniffa Professor Anne Dickinson et al.	Dermal dendritic cells but not Langerhans cells stimulate lymphocytes in an in vitro model of cutaneous graft-versus-host disease	2006
Dr Udo Holtick Dr Scott Marshall Professor Muzlifah Haniffa Professor Catharien Hilkens Dr Xiao Wang et al.	Investigating the role of dendritic cells in extracorporeal photopheresis using an in vitro model	2006
Professor Muzlifah Haniffa Dr Emma Speight	Painful leg ulcers and a rash in a patient with polycythaemia rubra vera	2006
Professor Muzlifah Haniffa Professor Nick Reynolds	Use of topical glycopyrrolate in Ross syndrome	2006
Bethan Sayers Professor Muzlifah Haniffa Julie Diboll Professor John Isaacs Professor Catharien Hilkens et al.	Generation of dexamethasone and vitamin D3 treated human monocyte derived dendritic cells with tolerogenic properties	2005
Professor Muzlifah Haniffa Dr James Lloyd Dr Clifford Lawrence	The role of a skin-imaging device as a diagnostic aid in a melanoma screening clinic	2005
Professor Muzlifah Haniffa Dr Emma Speight	Anetoderma secondary to lupus profundus in association with positive antiphospholipid antibodies	2004
Professor Muzlifah Haniffa Dr Suzy Leech Dr Sally Lynch Dr Nicholas Simpson	NBCCS secondary to an interstitial chromosome 9q deletion	2004
Professor Muzlifah Haniffa Dr Patrick Ormond Dr Clifford Lawrence	The predicting factors of the number of stages required for clearance in the treatment of basal cell carcinoma with Mohs' micrographic surgery	2004
Professor Muzlifah Haniffa	The frequency of positive patch test reactions in non atopic vs. atopic patients	2003
Professor Muzlifah Haniffa Dr Brian Angus Dr Simon Meggitt	Warty granuloma faciale	2003