Toggle Main Menu Toggle Search

Open Access padlockePrints

Secondary acute lymphoblastic leukaemia with 4:11 translocation following treatment for Hodgkin's disease

Lookup NU author(s): Dr Anne Lennard, Professor Graham Jackson, Dr Peter Carey, Dr Peter Middleton, Professor Stephen Proctor

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Abstract

It is apparent that treatment of Hodgkin's disease can be complicated by the development of secondary leukaemia. Most such leukaemias are of the non-lymphocytic type. We describe here a patient treated for Hodgkin's disease with chemo- and radiotherapy who developed secondary acute lymphoblastic leukaemia with a non-random chromosomal abnormality t(4;11). The frequency of such cases is assessed by a literature review and evidence for their pluripotent cell origin is discussed.


Publication metadata

Author(s): Lennard, A. L., Jackson, G. H., Carey, P. J., Bown, N., Middleton, P. G., Proctor, S. J.

Publication type: Article

Publication status: Published

Journal: Leukemia

Year: 1991

Volume: 5

Issue: 7

Pages: 624-627

Print publication date: 01/07/1991

ISSN (print): 0887-6924

ISSN (electronic): 1476-5551

PubMed id: 2072750


Share