Publications by Dr Peter Middleton - ePrints

Browsing publications by Dr Peter Middleton.

Newcastle Authors	Title	Year
Dr Ali Anwar Professor Anthony De Soyza Dr Sylvia Worthy Dr James Lordan Professor Christopher Ward et al.	Lack of association between KIR and HLA-C type and susceptibility to idiopathic bronchiectasis	2014
Dr Christian Harkensee Dr Peter Middleton Professor Andrew Gennery	Microsatellite scanning of the immunogenome associates MAPK14 and ELTD1 with graft-versus-host disease in hematopoietic stem cell transplantation	2013
Dr Ali Anwar Dr Sylvia Worthy Professor Stephen Bourke Dr James Lordan Professor Anthony De Soyza et al.	Phenotyping adults with non-cystic fibrosis bronchiectasis: A prospective observational cohort study	2013
Dr Christian Harkensee Dr Peter Middleton Professor Andrew Gennery	Microsatellite scanning of the immunogenome for associations with hematopoietic stem cell transplantation outcomes	2012
Dr Christian Harkensee Dr Peter Middleton Professor Andrew Gennery	Single nucleotide polymorphisms and outcome risk in unrelated mismatched hematopoietic stem cell transplantation: an exploration study	2012
Dr Christian Harkensee Dr Peter Middleton Professor Andrew Gennery	TNF-1031 single nucleotide polymorphism: An independent predictor of severe graft-versus-host disease?	2012
Dr Ali Anwar Professor Stephen Bourke Dr Peter Middleton Professor Christopher Ward Dr Robert Rutherford et al.	Efficacy of nebulised colomycin in patients with non-cystic fibrosis bronchiectasis colonised with Pseudomonas aeruginosa	2010
Dr Peter Middleton Jean Norden Professor Anne Dickinson	Association of vitamin D receptor polymorphisms with the outcome of allogeneic haematopoietic stem cell transplantation	2008
Dr Ali Anwar Professor Stephen Bourke Dr Peter Middleton Professor Christopher Ward Dr Robert Rutherford et al.	Effects of long-term low-dose azithromycin in patients with non-CF bronchiectasis	2008
Dr Peter Middleton Dr John Taylor	Progression of periodontal disease and interleukin-10 gene polymorphism	2008
Dr Iram Haq Professor Andrew Cant Dr Peter Middleton Professor Andrew Gennery	GvHD-associated cytokine polymorphisms do not associate with Omenn syndrome rather than T-B- SCID in patients with defects in RAG genes	2007
Dr Peter Middleton	Non-HLA Polymorphisms in Stem Cell Transplantation	2007
Dr Tryfonia Mainou-Fowler Jean Norden Dr Peter Middleton Professor Stephen Proctor Professor Anne Dickinson et al.	CD31 expression and gene polymorphisms in patients with B-cell chronic lymphocytic leukemia (B-CLL)	2006
Dr Udo Holtick Professor Anne Dickinson Dr Peter Middleton Professor Matthew Collin	Impact of mismatching CD1a, a dimorphic antigen-presenting molecule, on graft-versus-host disease after hematopoietic stem cell transplantation	2006
Jane Harrold Dr Peter Middleton Professor Anne Dickinson	Non-HLA polymorphism risk-factor analysis in unrelated haematopoietic stem cell transplants	2006
Professor Matthew Collin Professor Graham Jackson Dr Jennifer Cavet Dr Peter Middleton Professor Anne Dickinson et al.	The fate of human Langerhans cells in hematopoietic stem cell transplantation	2006
Dr Udo Holtick Dr Peter Middleton Jane Harrold Professor Anne Dickinson Professor Matthew Collin et al.	The MyD88 adapter-like (Mal) protein variant Leu 180, a candidate polymorphism for protection against graft versus host disease	2006
Dr Peter Middleton	TNFα and IL-10 in bone marrow transplantation: Does genotype matter?	2006
Dr Lucy Crossman Professor Stephen O'Brien Dr Peter Middleton	A gene polymorphism within the kinase domain of BCR-ABL and its effects on sensitivity to tyrosine kinase inhibitors	2005
Dr Lucy Crossman Professor Stephen O'Brien Dr Peter Middleton	A single nucleotide polymorphism in the coding region of ABL and its effects on sensitivity to imatinib	2005
Professor Christopher Ward Suzanne Scorfield Phil Botha Professor John Dark Dr Peter Middleton et al.	Association between the genotype of the TNF locus and acute rejection following lung transplant	2005
Professor Anne Dickinson Dr Peter Middleton	Beyond the HLA typing age: Genetic polymorphisms predicting transplant outcome	2005
Dr Peter Middleton Professor Anne Dickinson	CD1a is a dimorphic antigen-presenting protein that may be mismatched without increasing the risk of graft versus host disease	2005
Dr Peter Middleton Professor Anne Dickinson	Contributions of KIR genotype and HLA-C-encoded KIR ligands to the outcome of allogeneic hematopoietic stem cell transplantation	2005
Gary Cavanagh Professor Anne Dickinson Dr Peter Middleton	Donor CD31 genotype impacts on transplant complications after human leukocyte antigen-matched sibling allogeneic bone marrow transplantation	2005
Dr Lindsay Nicholson Professor Christopher Ward Professor John Dark Dr Peter Middleton	Genetic polymorphisms and bronchiolitis obliterans syndrome post lung transplantation	2005
Dr Trevor Booth Dr Peter Middleton Professor Graham Jackson Dr Jennifer Cavet Dr Xiao Wang et al.	Human langerhans cells in transplantation: Recipient cells survive conditioning but donor cells predominate at day 100	2005
Professor Graham Jackson Dr Jennifer Cavet Dr Trevor Booth Dr Peter Middleton Dr Xiao Wang et al.	Human Langerhans cells in transplantation: Recipient cells survive conditioning but donor cells predominate at day 100	2005
Dr Peter Middleton Jean Norden Professor Anne Dickinson	Vitamin D receptor (VDR) polymorphism and the risk of acute gvhd after allogeneic haematopoietic stem cell transplantation (HSCT)	2005
Dr Peter Middleton Jean Norden Professor Anne Dickinson	Vitamin D receptor polymorphism associates with the development of acute GvHD after allogeneic haematopoietic stem cell transplantation	2005
Professor Anne Dickinson Dr Hannah Cullup Dr Peter Middleton	Beyond HLA-typing: Genetic polymorphisms predicting transplant outcome	2004
Dr Peter Middleton	Discrimination of suballeles present at TNFd microsatellite locus using induced heteroduplex analysis	2004
Dr Hannah Cullup Dr Peter Middleton Professor Anne Dickinson	Environmental factors and not genotype influence the plasma level of interleukin-1 receptor antagonist in normal individuals	2004
Professor Anne Dickinson Dr Peter Middleton	Genetic polymorphisms predicting the outcome of bone marrow transplants	2004
Dr Ian Forrest Professor Christopher Ward Dr Peter Middleton	Genotypic risk factors for the development of the bronchiolitis oblitererans syndrome (BOS) after lung transplantation	2004
Professor Robert Taylor Anna Lewall Professor Stephen Proctor Dr Peter Middleton Emeritus Professor Doug Turnbull et al.	Mitochondrial DNA mutations in the haematopoietic system.	2004
Dr Peter Middleton Professor Anne Dickinson Mandy Jarvis Dr Jennifer Cavet Dr Hannah Cullup et al.	Clinical and genotypic risk factors for GvHD are modulated by prophylaxis: A multicentre cohort study of HLA matched sib-allo BMT	2003
Dr Peter Middleton Jean Norden Dr Hannah Cullup Dr Jennifer Cavet Professor Graham Jackson et al.	Oestrogen receptor α gene polymorphism associates with occurrence of graft-versus-host disease and reduced survival in HLA-matched sib-allo BMT	2003
Dr Hannah Cullup Professor Anne Dickinson Dr Jennifer Cavet Professor Graham Jackson Dr Peter Middleton et al.	Polymorphisms of interleukin-1α constitute independent risk factors for chronic graft-versus-host disease after allogeneic bone marrow transplantation	2003
Gary Cavanagh Dr Peter Middleton Professor Anne Dickinson Claire Chapman	Pre-treatment of human lymphocytes with CD31 peptide inhibits cellular proliferation in mixed lymphocyte culture	2003
Anna Lewall Dr Liewi Luo Professor Stephen Proctor Dr Peter Middleton Professor Robert Taylor et al.	Somatic mitochondrial DNA mutations in adult-onset leukaemia	2003
Dr Gail Stark Professor Anne Dickinson Professor Graham Jackson Dr Penelope Taylor Professor Stephen Proctor et al.	Tumour necrosis factor receptor type II 196M/R genotype correlates with circulating soluble receptor levels in normal subjects and with graft-versus-host disease after sibling allogeneic bone marrow transplantation	2003
Dr Jennifer Cavet Dr Hannah Cullup Dr Alison Dickinson Dr Peter Middleton	Donor IL-1 Ra gene polymorphisms affect in vitro and in vivo responses to CMV antigen	2002
Professor Anne Dickinson Dr Jennifer Cavet Dr Hannah Cullup Dr Xiao Wang Dr Mark Jarvis et al.	Predicting outcome in hematological stem cell transplantation	2002
Dr Peter Middleton Professor Anne Dickinson	Recipient cytokine genotypes for TNF-alpha and IL-10 and the minor histocompatibility antigens HY and CD31 codon 125 are not associated with occurrence or severity of acute GVHD in unrelated cord blood transplantation - A retrospective analysis	2002
Dr Peter Middleton Dr Hannah Cullup Professor Anne Dickinson Jean Norden Professor Graham Jackson et al.	Vitamin D receptor gene polymorphism associates with graft-versus-host disease and survival in HLA-matched sibling allogeneic bone marrow transplantation	2002
Diana Levett Dr Peter Middleton Mike Cole Dr Michael Reid	A demographic study of the clinical significance of minimal residual disease in children with acute lymphoblastic leukemia	2001
Dr Peter Middleton Dr Michael Tilby	Antibody recognition of melphalan adducts characterized using immobilized DNA: Enhanced alkylation of G-rich regions in cells compared to in vitro	2001
Dr Peter Middleton	Do adverse cytokine expression profiles in nonmyeloablative stem cell transplant (NST) recipients play a lesser role than in standard transplantation?	2001
Dr Hannah Cullup Professor Anne Dickinson Professor Graham Jackson Dr Peter Middleton	Donor interleukin 1 receptor antagonist genotype associated with acute graft-versus-host disease in human leucocyte antigen-matched sibling allogeneic transplants	2001
Professor Anne Dickinson Dr Jennifer Cavet Dr Hannah Cullup Dr Xiao Wang Dr Peter Middleton et al.	GvHD risk assessment in hematopoietic stem cell transplantation: Role of cytokine gene polymorphisms and an In Vitro human skin explant model	2001
Dr Annette Neylon Professor Stephen O'Brien Dr Peter Middleton	IL-4 gene polymorphism and outcome following sibling allogeneic bone marrow transplant	2001
Professor Anne Dickinson Jean Norden Dr Penelope Taylor Professor Graham Jackson Dr Peter Middleton et al.	Interferon-gamma and interleukin-6 gene polymorphisms associate with graft-versus-host disease in HLA-matched sibling bone marrow transplantation	2001
Jean Norden Dr Peter Middleton	Interleukin-10 (IL-10) gene polymorphisms and IL-10 production as predictors of transplant related complications in unrelated donor transplant recipients	2001
Dr Annette Neylon Professor Stephen O'Brien Dr Peter Middleton	The correlation of cytokine gene polymorphisms with outcome in chronic phase CML patients undergoing allogeneic BMT	2001
Dr Sally Coulthard Dr Christopher Howell Lynne Minto Dr Peter Middleton Professor Graham Jackson et al.	A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations	2000
Dr Peter Middleton Jean Norden Diana Levett Dr Mark Levasseur Professor Julie Irving et al.	Population-based study of the pattern of molecular markers of minimal residual disease in childhood and adult acute lymphoblastic leukemia: An assessment of the practical difficulty of representative sampling for trial purposes	2000
Dr Peter Middleton Professor Anne Dickinson	Cytokine gene polymorphism of the recipient influences the development of acute GvHD in HLA mismatched cord blood transplants	1999
Dr Peter Middleton Dr Jennifer Cavet Dr Sally Davies Professor Anne Dickinson	Cytokine gene polymorphisms (TNF alpha and 1L-10) associate with early mortality and acute GVHD in HLA identical sibling transplants	1999
Dr Peter Middleton Jean Norden Dr Jennifer Cavet Professor Graham Jackson Professor Anne Dickinson et al.	Interleukin-6 gene polymorphism associated with absence of severe graft-versus-host-disease in allogeneic BMT: A possible genetic protection factor.	1999
Dr Jennifer Cavet Dr Peter Middleton Professor Anne Dickinson	Recipient tumor necrosis factor-alpha and interleukin-10 gene polymorphisms associate with early mortality and acute graft-versus-host disease severity in HLA-matched sibling bone marrow transplants	1999
Dr Peter Middleton Dr Penelope Taylor Professor Graham Jackson Professor Stephen Proctor Professor Anne Dickinson et al.	Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants	1998
Dr Mark Levasseur Dr Peter Middleton Dr Brian Angus Professor Stephen Proctor Jean Norden et al.	c-MYC gene abnormalities in high grade and centroblastic-centrocytic Non-Hodgkins Lymphoma	1995
Dr John Taylor Professor Stephen Proctor Dr Peter Middleton	Characterization of non-concordance in the T-cell receptor γ chain genes at presentation and clinical relapse in acute lymphoblastic leukemia	1994
Dr Mark Levasseur Professor Graham Jackson Dr Jennifer Kernahan Professor Stephen Proctor Dr Peter Middleton et al.	Relapse of acute lymphoblastic leukaemia 14 years after presentation: use of molecular techniques to confirm true re-emergence	1994
Dr Peter Middleton Dr Penelope Taylor Dr Michael Reid Professor Graham Jackson Professor Stephen Proctor et al.	Alpha interferon gene deletions in adults, children and infants with acute lymphoblastic leukemia	1991
Dr John Taylor Professor Stephen Proctor Dr Peter Middleton	Detection of T-cell receptor gamma chain V gene rearrangements using the polymerase chain reaction: application to the study of clonal disease cells in acute lymphoblastic leukemia	1991
Dr Anne Lennard Professor Graham Jackson Dr Peter Carey Dr Peter Middleton Professor Stephen Proctor et al.	Secondary acute lymphoblastic leukaemia with 4:11 translocation following treatment for Hodgkin's disease	1991
Dr Peter Middleton Dr Michael Reid Professor Stephen Proctor	De novo Ph negative T-cell lymphoblastic leukaemia associated with BCR gene rearrangement	1990