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Role of N-Terminal Pro-Brain Natriuretic Peptide and Cystatin C to Estimate Renal Function in Patients With and Without Heart Failure

Lookup NU author(s): Professor Ioakim SpyridopoulosORCiD


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Blood cystatin C has increasingly been used as an endogenous marker for estimating glomerular filtration rate (GFR) and evaluating prognosis in patients with acute or chronic heart failure. The goal of the study was to investigate the impact of heart failure on the determination of renal function based on cystatin C or creatinine in nonacute cardiac patients. A total of 880 consecutive and clinically stable patients with heart disease were prospectively evaluated. Serum N-terminal pro-brain natriuretic peptide (NT-pro-BNP) showed a stronger correlation with cystatin C (r = 0.60, p

Publication metadata

Author(s): Linzbach S, Samigullin A, Yilmaz S, Tsioga M, Zeiher AM, Spyridopoulos I

Publication type: Article

Publication status: Published

Journal: American Journal of Cardiology

Year: 2009

Volume: 103

Issue: 8

Pages: 1128-1133

ISSN (print): 0002-9149

ISSN (electronic): 1879-1913

Publisher: Excerpta Medica, Inc.


DOI: 10.1016/j.amjcard.2009.01.009


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