Browse by author
Lookup NU author(s): Dr Chris LambORCiD,
Dr Jonathan Hanson,
Dr John Mansfield
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Background: Identifying Crohn's disease recurrence in symptomatic patients after ileocaecal resection is difficult. The aim of this study was to evaluate faecal concentrations of granulocyte degradation products in this setting. Methods: A postoperative cohort of 13 patients was followed prospectively for 1 year with regular faecal calprotectin (FC) and lactoferrin (FL) measurements. A second postoperative cohort (median 24 months after resection) of 104 patients provided a single stool sample. Faecal measurements were compared with symptom diaries, the Harvey Bradshaw Index, endoscopic examination, C-reactive protein and platelet measurement. Results: In the uncomplicated course, both markers normalized within 2 months. Both FC and FL correlated significantly with Harvey Bradshaw Index (P
Author(s): Lamb CA, Mohiuddin MK, Gicquel J, Neely D, Bergin FG, Hanson JM, Mansfield JC
Publication type: Article
Publication status: Published
Journal: British Journal of Surgery
ISSN (print): 0007-1323
ISSN (electronic): 1365-2168
Publisher: John Wiley & Sons Ltd.
Altmetrics provided by Altmetric