Toggle Main Menu Toggle Search

Open Access padlockePrints

Browsing publications by Dr Chris Lamb.

Newcastle AuthorsTitleYearFull text
Dr Chris Lamb
Ambulatory care management of 69 patients with acute severe ulcerative colitis in comparison to 695 inpatients: insights from a multicentre UK cohort study2022
Dr Chris Lamb
Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in 1 inflammatory bowel disease patients treated with infliximab and vedolizumab2022
Andrea Masi
Dr Chris Lamb
Dr Simon Cockell
Dr Jonathan Coxhead
Professor Nicholas Embleton
et al.
Distinct gene expression profiles between human preterm- and adult-derived intestinal organoids exposed to Enterococcus faecalis: A pilot study2022
Dr Marcus Brookes
Dr Chris Lamb
Inflammatory Bowel Disease patient-reported quality assessment should drive service improvement: a national survey of UK IBD units and patients2022
Dr David Houghton
Dr Yi Ng
Dr Renae Stefanetti
Paula Hynd
Dr Christopher Stewart
et al.
Phase II feasibility study of the efficacy, tolerability and impact on the gut microbiome of a low residue (fibre) diet in adult patients with mitochondrial disease2022
Dr Claire Granger
Dr Chris Lamb
Professor Nicholas Embleton
Lauren Beck
Andrea Masi
et al.
sIgA in preterm infants: determination of normal values in breast milk and stool2022
Dr Chris Lamb
The future of precision medicine to predict outcomes and control tissue remodeling in inflammatory bowel disease2022
Dr Chris Lamb
Withdrawal of the British Society of Gastroenterology IBD risk grid for COVID-19 severity2022
Dr Chris Lamb
Dr David Nylander
Enterobius vermicularis infection associated with positive faecal occult blood testing and eosinophilia2021
Dr Chris Lamb
Anti-SARS-CoV2 antibody responses are attenuated in patients with inflammatory bowel disease treated with infliximab2021
Dr Sesha Subramanian
Dr Marcus Brookes
Dr Chris Lamb
Assessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case-control study2021
Andrea Masi
Dr Beate Haugk
Dr Chris Lamb
Professor Linda Sharp
Professor James Shaw
et al.
Endoscopic ultrasound (EUS) guided fine needle biopsy (FNB) formalin preserved paraffin embedded (FFPE) pancreatic tissue samples are a potential resource for microbiota analysis2021
Dr Chris Lamb
Inflammatory Bowel Disease Clinical Activity Is Associated with COVID-19 Severity Especially in Younger Patients2021
Dr Chris Lamb
Inflammatory Bowel Disease Clinical Service Recovery during the COVID-19 Pandemic2021
Dr Chris Lamb
Jamie Macdonald
Infliximab and immunomodulators reduce the immunogenicity of a single dose of ChAdOx1 nCoV-19 and BNT162b2 SARS-CoV-2 vaccines2021
Dr Claire Granger
Professor Nicholas Embleton
Dr Jeremy Palmer
Dr Chris Lamb
Dr Janet Berrington
et al.
Maternal breastmilk, infant gut microbiome and the impact on preterm infant health2021
Dr Chris Lamb
Dr John Mansfield
Oral ferric maltol does not adversely affect the intestinal microbiome of patients or mice, but ferrous sulphate does2021
Dr Meghan Acres
Dr Gill Hulme
Dr Christopher Carey
Dr John Mansfield
Professor John Kirby
et al.
Regulation and role of αE integrin and gut homing integrins in migration and retention of intestinal lymphocytes during inflammatory bowel disease2021
Dr Chris Lamb
Results of the Seventh Scientific Workshop of ECCO: Precision Medicine in IBD – Challenges and Future Directions2021
Dr Chris Lamb
Dr Marcus Brookes
Dr Sesha Subramanian
Risk of severe COVID-19 outcomes associated with inflammatory bowel disease medications - reassuring insights from the United Kingdom PREPARE-IBD multicentre cohort study2021
Dr Ashley Hart
Jamie Macdonald
Dr Sesha Subramanian
Dr Ramesh Arasaradnam
Dr Chris Lamb
et al.
SARS-CoV-2 vaccination for patients with inflammatory bowel disease: a British Society of Gastroenterology Inflammatory Bowel Disease section and IBD Clinical Research Group position statement2021
Dr Nicola Wyatt
Dr Ally Speight
Dr Christopher Stewart
Professor John Kirby
Dr Chris Lamb
et al.
Targeting leukocyte trafficking in inflammatory bowel disease2021
Dr Christopher Stewart
Dr John Mansfield
Dr Darren Smith
Dr Simon Bridge
Dr Chris Lamb
et al.
The Impact of NOD2 Genetic Variants on the Gut Mycobiota in Crohn’s Disease Patients in Remission and Individuals Without Gastrointestinal Inflammation2021
Dr Chris Lamb
Dr Marcus Brookes
The impact of SARS-CoV-2 variants on IBD management2021
Andrea Masi
Dr Sara Koo
Dr Chris Lamb
Professor Linda Sharp
Dr James Hampton
et al.
Using faecal immunochemical test (FIT) undertaken in a national screening programme for large-scale gut microbiota analysis2021
Dr Chris Lamb
Adaptations to the British Society of Gastroenterology guidelines on the management of acute severe UC in the context of the COVID-19 pandemic: a RAND appropriateness panel2020
Dr Chris Lamb
British Society of Gastroenterology guidance for management of inflammatory bowel disease during the COVID-19 pandemic2020
Dr Chris Lamb
Consensus Standards of Healthcare for Adults and Children with Inflammatory Bowel Disease in the United Kingdom2020
Dr Laura Jardine
Dr Urszula Cytlak-Chaudhuri
Dr Merry Gunawan
Dr Gary Reynolds
Dr Kile Green
et al.
Donor monocyte-derived macrophages promote human acute graft-versus-host disease2020
Andrea Masi
Professor Nicholas Embleton
Dr Chris Lamb
Grace Young
Dr Claire Granger
et al.
Human milk oligosaccharide DSLNT and gut microbiome in preterm infants predicts necrotising enterocolitis2020
Dr Chris Lamb
Organisational changes and challenges for inflammatory bowel disease services in the United Kingdom during the COVID-19 pandemic2020
Dr Lucy Crouch
Dr Arnaud Basle
Dr Chris Lamb
Dr Christopher Stewart
Kate Cooke
et al.
Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown2020
Dr Chris Lamb
British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults2019
Colette Kirk
Dr Chris Lamb
Dr Nicholas Thompson
Elevated Whole-Blood Manganese Levels in Adult Patients Prescribed "Manganese-Free" Home Parenteral Nutrition2019
Dr David Swan
Dr Chris Lamb
Dr Karin Engelhardt
Dr Rui Chen
Dr Yuchun Ding
et al.
Immunodeficiency, autoimmune thrombocytopenia and enterocolitis caused by autosomal recessive deficiency of PIK3CD-encoded phosphoinositide 3-kinase δ2019
Dr Chris Lamb
Dr John Mansfield
Professor John Kirby
The Importance of Molecular Immune Investigation in Therapeutic Clinical Development for Biomarker Assessment2019
Dr Chris Lamb
Trial summary and protocol for a phase II randomised placebo-controlled double-blinded trial of Interleukin 1 blockade in Acute Severe Colitis: the IASO trial2019
Dr Christopher Stewart
Dr Chris Lamb
Using formalin fixed paraffin embedded tissue to characterize the preterm gut microbiota in necrotising enterocolitis and spontaneous isolated perforation using marginal and diseased tissue2019
Dr Chris Lamb
Dr John Mansfield
NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease2018
Dr Chris Lamb
Anna Long
Dr John Mansfield
Professor John Kirby
AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation2018
Dr Chris Lamb
Professor John Kirby
Donor intravascular monocyte trafficking: A potential therapeutic target for primary graft dysfunction following lung transplantation?2018
Dr Chris Lamb
Gut-selective integrin-targeted therapies for inflammatory bowel disease2018
Dr Chris Lamb
Dr John Mansfield
The Impact of NOD2 Variants on Fecal Microbiota in Crohn's Disease and Controls Without Gastrointestinal Disease2018
Dr Chris Lamb
Dr John Mansfield
Anna Long
Maria Price
Dr Graeme O'Boyle
et al.
aEß7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis2017
Dr Chris Lamb
Dr John Mansfield
Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY72017
Dr Chris Lamb
Dr John Mansfield
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease2017
Professor Nicholas Embleton
Dr Janet Berrington
Professor John Kirby
Dr Chris Lamb
Professor Stephen Rushton
et al.
Mechanisms Affecting the Gut of Preterm Infants in Enteral Feeding Trials2017
Dr Chris Lamb
Dr John Mansfield
A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis2016
Dr Chris Lamb
Dr John Mansfield
Professor John Kirby
Association Between Response to Etrolizumab and Expression of Integrin alpha E and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis2016
Dr Jess Dyson
Dr Chris Lamb
Dr Steven Masson
Dr Mark Hudson
Dr Christian Dipper
et al.
Implementation of a “care bundle” improves the management of patients admitted to hospital with decompensated cirrhosis2016
Dr Chris Lamb
Relapse after withdrawal from anti-TNF therapy for inflammatory bowel disease: an observational study, plus systematic review and meta-analysis2016
Dr Chris Lamb
Dr John Mansfield
Jennifer Kirby
AlphaE (alpha E) integrin protein and gene expression are augmented in the ileum relative to the colon in Crohn's disease2015
Dr Chris Lamb
Anti-TNF withdrawal in IBD: Relapse and recapture rates and predictive factors from 160 patients in a pan-UK study2015
Dr Jess Dyson
Dr Ahmed Elsharkawy
Dr Chris Lamb
Dr Ahmad Al-Rifai
Professor Julia Newton
et al.
Fatigue in primary sclerosing cholangitis is associated with sympathetic over-activity and increased cardiac output2015
Dr Jess Dyson
Dr Chris Lamb
Dr Mark Hudson
Dr Stuart McPherson
Implementation and impact of a care bundle for the management of patients with decompensated liver disease2015
Dr Chris Lamb
Dr John Mansfield
Predicting inflammatory pathology at capsule enteroscopy: what is the utility of a raised faecal calprotectin?2015
Dr Michael Keir
Dr John Mansfield
Dr Chris Lamb
Professor John Kirby
AlphaE integrin expression as a predictive biomarker for induction of clinical remission by etrolizumab: Analysis of a phase II trial in moderate-to-severely active ulcerative colitis2014
Dr Chris Lamb
Anti-TNF Withdrawal in IBD: Initial Results from a Pan-UK Study2014
Stephen Douglass
Dr Annette Meeson
Dr Dorota Overbeck-Zubrzycka
Dr John Brain
Dr Chris Lamb
et al.
Breast cancer metastasis: demonstration that FOXP3 regulates CXCR4 expression and the response to CXCL122014
Dr John Mansfield
Dr Chris Lamb
Professor John Kirby
Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial2014
Dr Chris Lamb
Maria Price
Dr John Mansfield
Faecal Calprotectin Is Useful In Predicting Long Term Disease Recurrence In Post-operative Crohn’s2014
Dr Chris Lamb
Dr John Mansfield
The Impact Of NOD2 Variants on Gut Microbiota in Crohn’s Disease and Healthy Controls2014
Dr Carl Gamble
Dr Chris Lamb
Dr John Mansfield
Thiopurine withdrawal during sustained clinical remission in inflammatory bowel disease: relapse and recapture rates, with predictive factors in 237 patients2014
Dr Chris Lamb
Dr John Mansfield
Dr Graeme O'Boyle
Professor David Jones
Jennifer Kirby
et al.
Ulcerative colitis: The alpha E beta 7 integrin is associated with a high frequency of Th17, Th1 and Th17/Th1 CD4 lymphocytes2014
Dr Chris Lamb
Dr John Mansfield
Dr Graeme O'Boyle
Professor David Jones
Dr Michael Keir
et al.
Ulcerative Colitis: The Alpha-e-beta-7 Integrin Is Associated With A High Frequency Of Th17, Th1 And Th17/th1 Cd4 Lymphocytes2014
Dr Chris Lamb
Dr Lily Lamb
Dr John Mansfield
Sexually transmitted infections manifesting as proctitis2013
Dr Chris Lamb
Dr Graeme O'Boyle
Professor David Jones
Dr John Mansfield
Professor John Kirby
et al.
Blockade of the B7 integrin prevents adherence of t lymphocytes to MAdCAM-1 in an in vitro model of vascular microcirculation post-capillary shear flow2012
Dr Graeme O'Boyle
Christopher Fox
Dr Hannah Walden
Dr Joe Willet
Dr Emily Mavin
et al.
Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation2012
Dr Chris Lamb
Developing an endoscopic mucosal resection service in a district general hospital2012
Dr Chris Lamb
Rifaximin for recurrent hepatic encephalopathy following transjugular intrahepatic portosystemic shunt insertion2012
Dr Chris Lamb
Maria Price
Dr John Mansfield
A real life retrospective analysis of drug expenditure reveals no significant cost difference between infliximab and adalimumab in the treatment of Adult Crohn's Disease2011
Dr Chris Lamb
Gastroenterology 2010: Maximising patient care and safety while minimising unnecessary cost2011
Dr Chris Lamb
Mick Eltringham
Generic medical and surgical endoscopy training lists can improve the number of opportunities for training in colonoscopy2011
Dr Chris Lamb
Dr John Mansfield
Measurement of faecal calprotectin and lactoferrin in inflammatory bowel disease2011
Dr Chris Lamb
Maria Price
Professor David Jones
Dr John Mansfield
Patients with Crohn's Disease report high levels of fatigue during a symptomatic disease flare2011
Dr Chris Lamb
Venkatesh Kanakala
Stephen Attwood
Clinical lesson: eosinophilic oesophagitis, a new diagnosis to swallow2010
Dr Sohom Maitra
Dr Chris Lamb
Dr Andrew McLean-Tooke
Dr Gavin Spickett
Dr John Mansfield
et al.
Anti-tissue transglutaminase antibodies in the follow-up of adult coeliac disease2009
Dr Chris Lamb
Mohamed Mohiuddin
Fintan Bergin
Dr Jonathan Hanson
Dr John Mansfield
et al.
Faecal calprotectin or lactoferrin can identify postoperative recurrence in Crohn's disease2009
Dr Chris Lamb
Mohamed Mohiuddin
Fintan Bergin
Dr Jonathan Hanson
Dr John Mansfield
et al.
Longitudinal Study of Faecal Markers Following Ileal Resection in Crohn's Disease: Do Calprotectin and Lactoferrin Normalise Post Operatively?2009
Mohamed Mohiuddin
Dr Chris Lamb
Fintan Bergin
Dr Jonathan Hanson
Dr John Mansfield
et al.
Post Operative Crohn's Disease: The Role of Faecal Calprotectin and Lactoferrin in Assessing Disease Recurrence Following Ileal Resection2009
Stephen Attwood
Dr Chris Lamb
Eosinophilic oesophagitis and other non-reflux inflammatory conditions of the oesophagus: Diagnostic imaging and management2008