Professor Chris Lamb
| 2024 British Society of Gastroenterology Guidelines On Colorectal Surveillance In Inflammatory Bowel Disease: An Update From 2010 (Standard Operating Procedure) | 2024 |
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Professor Chris Lamb
| Biologic therapy for inflammatory bowel disease: Real-world comparative effectiveness and impact of drug sequencing in 13,222 patients within the UK IBD BioResource | 2024 |
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Dr Nicola Wyatt
Dr Hannah Watson
Jennifer Doyle
Dr Ally Speight
Professor Christopher Stewart
et al. | Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research | 2024 |
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Dr Nicola Wyatt
Dr Hannah Watson
Dr Dean Allerton
Michelle Bardgett
Dr Emma Clark
et al. | Defining predictors of responsiveness to advanced therapies in Crohn’s disease and ulcerative colitis: Protocol for the IBD-RESPONSE and nested CD-metaRESPONSE prospective, multicentre, observational cohort study in precision medicine | 2024 |
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Professor Chris Lamb
| Evaluation of emergency hospital admissions for inflammatory bowel disease as a possible marker of quality of care of British IBD inflammatory bowel disease units | 2024 |
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Professor Chris Lamb
| Inflammatory bowel disease has no borders: engaging patients as partners to deliver global, equitable and holistic health care | 2024 |
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Suzanne Alderson
Helen Croft
Professor Chris Lamb
Professor Colin Rees
| Launch of UK primary care diagnostic pathways for lower gastrointestinal symptoms in adults and children | 2024 |
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Dr Abi Gault
Dr Linda Hogarth
Dr Kristian Williams
Professor Alastair Greystoke
Professor Neil Rajan
et al. | Monitoring immunE DysregulAtion foLLowing Immune checkpOint-inhibitioN (MEDALLION): protocol for an observational cancer immunotherapy cohort study | 2024 |
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Dr Robert Mulligan
Professor Chris Lamb
| Vedolizumab prophylaxis against postoperative Crohn’s disease recurrence | 2024 |
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Professor Chris Lamb
| British Society of Gastroenterology interim framework for addressing the COVID-19-related backlog in inflammatory bowel disease colorectal cancer surveillance | 2023 |
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Dr John Mansfield
Professor Chris Lamb
| Conserved γδ T cell selection by BTNL proteins limits progression of human inflammatory bowel disease | 2023 |
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Professor Chris Lamb
| DECIDE: Delphi Expert Consensus Statement on Inflammatory Bowel Disease Dysplasia Shared Management Decision-Making | 2023 |
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Dr Steven Brown
Professor Chris Lamb
| Development of a core descriptor set for Crohn's anal fistula | 2023 |
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Dr Ally Speight
Professor Chris Lamb
| Establishing key performance indicators for inflammatory bowel disease in the UK | 2023 |
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Professor Chris Lamb
Professor Sophie Hambleton
Dr Ally Speight
| Genomic diagnosis and care co-ordination for monogenic inflammatory bowel disease in children and adults: consensus guideline on behalf of the British Society of Gastroenterology and British Society of Paediatric Gastroenterology, Hepatology and Nutrition | 2023 |
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Dr Kristian Williams
Abigail Gault
Dr Amy Anderson
Professor Christopher Stewart
Professor Chris Lamb
et al. | Immune-related adverse events in checkpoint blockade: Observations from human tissue and therapeutic considerations | 2023 |
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Professor Chris Lamb
| Neutralising antibody potency against SARS-CoV-2 wild-type and Omicron BA.1 and BA.4/5 variants in infliximab and vedolizumab treated patients with inflammatory bowel disease after three doses of COVID-19 vaccine (CLARITY IBD): a prospective multicentre cohort study (CLARITY) | 2023 |
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Professor Chris Lamb
| Opioid use and associated factors in 1676 patients with inflammatory bowel disease: a multicentre quality improvement project | 2023 |
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Professor Chris Lamb
| Vaccine escape, increased breakthrough and reinfection in infliximab-treated patients with IBD during the Omicron wave of the SARS-CoV-2 pandemic | 2023 |
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Professor Chris Lamb
| Withdrawal of infliximab or concomitant immunosuppressant therapy in patients with Crohn's disease on combination therapy (SPARE): a multicentre, open-label, randomised controlled trial | 2023 |
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Professor Chris Lamb
| Withdrawal of the British Society of Gastroenterology IBD risk grid for COVID-19 severity | 2023 |
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Professor Chris Lamb
| Ambulatory care management of 69 patients with acute severe ulcerative colitis in comparison to 695 inpatients: insights from a multicentre UK cohort study | 2022 |
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Professor Chris Lamb
| Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in 1 inflammatory bowel disease patients treated with infliximab and vedolizumab | 2022 |
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Andrea Masi
Professor Chris Lamb
Dr Simon Cockell
Dr Jonathan Coxhead
Professor Nicholas Embleton
et al. | Distinct gene expression profiles between human preterm- and adult-derived intestinal organoids exposed to Enterococcus faecalis: A pilot study | 2022 |
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Professor Chris Lamb
| Editorial: quality assessment in IBD in high resource countries can lead to quality improvement clues for IBD management worldwide—authors' reply | 2022 |
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Professor Chris Lamb
| Inflammatory Bowel Disease Clinical Activity Is Associated with COVID-19 Severity Especially in Younger Patients | 2022 |
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Dr Marcus Brookes
Professor Chris Lamb
| Inflammatory Bowel Disease patient-reported quality assessment should drive service improvement: a national survey of UK IBD units and patients | 2022 |
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Anna Long
Dr Christopher Carey
Professor Chris Lamb
| Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy | 2022 |
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Professor Chris Lamb
Dr John Mansfield
| Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility | 2022 |
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Professor Janet Berrington
Emeritus Professor John Kirby
Lauren Beck
Professor Chris Lamb
Professor Christopher Stewart
et al. | Mechanisms affecting the gut of preterm infants in enteral feeding trials: a nested cohort within a randomised controlled trial of lactoferrin | 2022 |
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Dr David Houghton
Dr Yi Ng
Dr Renae Stefanetti
Paula Hynd
Professor Christopher Stewart
et al. | Phase II feasibility study of the efficacy, tolerability and impact on the gut microbiome of a low residue (fibre) diet in adult patients with mitochondrial disease | 2022 |
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Dr Claire Granger
Professor Chris Lamb
Professor Nicholas Embleton
Lauren Beck
Andrea Masi
et al. | sIgA in preterm infants: determination of normal values in breast milk and stool | 2022 |
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Lauren Beck
Andrea Masi
Professor Chris Lamb
Rachel Smith
Dr Jonathan Coxhead
et al. | Strain-specific impacts of probiotics are a significant driver of gut microbiome development in very preterm infants | 2022 |
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Professor Chris Lamb
| The future of precision medicine to predict outcomes and control tissue remodeling in inflammatory bowel disease | 2022 |
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Professor Chris Lamb
| Treatment adaptations and outcomes of patients experiencing inflammatory bowel disease flares during the early COVID-19 pandemic: the PREPARE-IBD multicentre cohort study | 2022 |
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Professor Chris Lamb
Dr David Nylander
| Enterobius vermicularis infection associated with positive faecal occult blood testing and eosinophilia | 2021 |
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Professor Chris Lamb
| Anti-SARS-CoV2 antibody responses are attenuated in patients with inflammatory bowel disease treated with infliximab | 2021 |
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Dr Sesha Subramanian
Dr Marcus Brookes
Professor Chris Lamb
| Assessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case-control study | 2021 |
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Andrea Masi
Dr Beate Haugk
Professor Chris Lamb
Professor Linda Sharp
Professor James Shaw
et al. | Endoscopic ultrasound (EUS) guided fine needle biopsy (FNB) formalin preserved paraffin embedded (FFPE) pancreatic tissue samples are a potential resource for microbiota analysis | 2021 |
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Andrea Masi
Professor Nicholas Embleton
Professor Chris Lamb
Grace Young
Dr Claire Granger
et al. | Human milk oligosaccharide DSLNT and gut microbiome in preterm infants predicts necrotising enterocolitis | 2021 |
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Professor Chris Lamb
| Inflammatory Bowel Disease Clinical Service Recovery during the COVID-19 Pandemic | 2021 |
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Professor Chris Lamb
Jamie Macdonald
| Infliximab and immunomodulators reduce the immunogenicity of a single dose of ChAdOx1 nCoV-19 and BNT162b2 SARS-CoV-2 vaccines | 2021 |
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Dr Claire Granger
Professor Nicholas Embleton
Dr Jeremy Palmer
Professor Chris Lamb
Professor Janet Berrington
et al. | Maternal breastmilk, infant gut microbiome and the impact on preterm infant health | 2021 |
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Professor Chris Lamb
Dr John Mansfield
| Oral ferric maltol does not adversely affect the intestinal microbiome of patients or mice, but ferrous sulphate does | 2021 |
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Dr Meghan Acres
Dr Gill Hulme
Dr Christopher Carey
Dr John Mansfield
Emeritus Professor John Kirby
et al. | Regulation and role of αE integrin and gut homing integrins in migration and retention of intestinal lymphocytes during inflammatory bowel disease | 2021 |
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Professor Chris Lamb
| Results of the Seventh Scientific Workshop of ECCO: Precision Medicine in IBD – Challenges and Future Directions | 2021 |
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Professor Chris Lamb
Dr Marcus Brookes
Dr Sesha Subramanian
| Risk of severe COVID-19 outcomes associated with inflammatory bowel disease medications - reassuring insights from the United Kingdom PREPARE-IBD multicentre cohort study | 2021 |
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Dr Ashley Hart
Jamie Macdonald
Dr Sesha Subramanian
Dr Ramesh Arasaradnam
Professor Chris Lamb
et al. | SARS-CoV-2 vaccination for patients with inflammatory bowel disease: a British Society of Gastroenterology Inflammatory Bowel Disease section and IBD Clinical Research Group position statement | 2021 |
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Dr Nicola Wyatt
Dr Ally Speight
Professor Christopher Stewart
Emeritus Professor John Kirby
Professor Chris Lamb
et al. | Targeting leukocyte trafficking in inflammatory bowel disease | 2021 |
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Professor Christopher Stewart
Dr John Mansfield
Dr Darren Smith
Dr Simon Bridge
Professor Chris Lamb
et al. | The Impact of NOD2 Genetic Variants on the Gut Mycobiota in Crohn’s Disease Patients in Remission and Individuals Without Gastrointestinal Inflammation | 2021 |
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Professor Chris Lamb
Dr Marcus Brookes
| The impact of SARS-CoV-2 variants on IBD management | 2021 |
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Andrea Masi
Dr Sara Koo
Professor Chris Lamb
Professor Linda Sharp
Dr James Hampton
et al. | Using faecal immunochemical test (FIT) undertaken in a national screening programme for large-scale gut microbiota analysis | 2021 |
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Professor Chris Lamb
| Adaptations to the British Society of Gastroenterology guidelines on the management of acute severe UC in the context of the COVID-19 pandemic: a RAND appropriateness panel | 2020 |
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Professor Chris Lamb
| British Society of Gastroenterology guidance for management of inflammatory bowel disease during the COVID-19 pandemic | 2020 |
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Professor Chris Lamb
| Consensus Standards of Healthcare for Adults and Children with Inflammatory Bowel Disease in the United Kingdom | 2020 |
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Dr Laura Jardine
Dr Urszula Cytlak-Chaudhuri
Dr Merry Gunawan
Dr Gary Reynolds
Dr Kile Green
et al. | Donor monocyte-derived macrophages promote human acute graft-versus-host disease | 2020 |
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Professor Chris Lamb
| Organisational changes and challenges for inflammatory bowel disease services in the United Kingdom during the COVID-19 pandemic | 2020 |
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Dr Lucy Crouch
Dr Arnaud Basle
Professor Chris Lamb
Professor Christopher Stewart
Kate Cooke
et al. | Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown | 2020 |
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Professor Chris Lamb
| British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults | 2019 |
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Colette Kirk
Professor Chris Lamb
Dr Nicholas Thompson
| Elevated Whole-Blood Manganese Levels in Adult Patients Prescribed "Manganese-Free" Home Parenteral Nutrition | 2019 |
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Dr David Swan
Professor Chris Lamb
Dr Karin Engelhardt
Dr Rui Chen
Dr Yuchun Ding
et al. | Immunodeficiency, autoimmune thrombocytopenia and enterocolitis caused by autosomal recessive deficiency of PIK3CD-encoded phosphoinositide 3-kinase δ | 2019 |
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Professor Chris Lamb
Dr John Mansfield
Emeritus Professor John Kirby
| The Importance of Molecular Immune Investigation in Therapeutic Clinical Development for Biomarker Assessment | 2019 |
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Professor Chris Lamb
| Trial summary and protocol for a phase II randomised placebo-controlled double-blinded trial of Interleukin 1 blockade in Acute Severe Colitis: the IASO trial | 2019 |
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Professor Christopher Stewart
Professor Chris Lamb
| Using formalin fixed paraffin embedded tissue to characterize the preterm gut microbiota in necrotising enterocolitis and spontaneous isolated perforation using marginal and diseased tissue | 2019 |
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Professor Chris Lamb
Dr John Mansfield
| NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease | 2018 |
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Professor Chris Lamb
Anna Long
Dr John Mansfield
Emeritus Professor John Kirby
| AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation | 2018 |
|
Professor Chris Lamb
Emeritus Professor John Kirby
| Donor intravascular monocyte trafficking: A potential therapeutic target for primary graft dysfunction following lung transplantation? | 2018 |
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Professor Chris Lamb
| Gut-selective integrin-targeted therapies for inflammatory bowel disease | 2018 |
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Professor Chris Lamb
Dr John Mansfield
| The Impact of NOD2 Variants on Fecal Microbiota in Crohn's Disease and Controls Without Gastrointestinal Disease | 2018 |
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Professor Chris Lamb
Dr John Mansfield
Anna Long
Maria Price
Dr Graeme O'Boyle
et al. | aEß7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis | 2017 |
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Professor Chris Lamb
Dr John Mansfield
| Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7 | 2017 |
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Professor Chris Lamb
Dr John Mansfield
| Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease | 2017 |
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Professor Nicholas Embleton
Professor Janet Berrington
Emeritus Professor John Kirby
Professor Chris Lamb
Professor Stephen Rushton
et al. | Mechanisms Affecting the Gut of Preterm Infants in Enteral Feeding Trials | 2017 |
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Professor Chris Lamb
Dr John Mansfield
| A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis | 2016 |
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Professor Chris Lamb
Dr John Mansfield
Emeritus Professor John Kirby
| Association Between Response to Etrolizumab and Expression of Integrin alpha E and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis | 2016 |
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Dr Jess Dyson
Professor Chris Lamb
Dr Steven Masson
Dr Mark Hudson
Dr Christian Dipper
et al. | Implementation of a “care bundle” improves the management of patients admitted to hospital with decompensated cirrhosis | 2016 |
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Professor Chris Lamb
| Relapse after withdrawal from anti-TNF therapy for inflammatory bowel disease: an observational study, plus systematic review and meta-analysis | 2016 |
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Professor Chris Lamb
Dr John Mansfield
Jennifer Kirby
| AlphaE (alpha E) integrin protein and gene expression are augmented in the ileum relative to the colon in Crohn's disease | 2015 |
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Professor Chris Lamb
| Anti-TNF withdrawal in IBD: Relapse and recapture rates and predictive factors from 160 patients in a pan-UK study | 2015 |
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Dr Jess Dyson
Dr Ahmed Elsharkawy
Professor Chris Lamb
Dr Ahmad Al-Rifai
Emerita Professor Julia Newton
et al. | Fatigue in primary sclerosing cholangitis is associated with sympathetic over-activity and increased cardiac output | 2015 |
|
Dr Jess Dyson
Professor Chris Lamb
Dr Mark Hudson
Professor Stuart McPherson
| Implementation and impact of a care bundle for the management of patients with decompensated liver disease | 2015 |
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Professor Chris Lamb
Dr John Mansfield
| Predicting inflammatory pathology at capsule enteroscopy: what is the utility of a raised faecal calprotectin? | 2015 |
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Dr Michael Keir
Dr John Mansfield
Professor Chris Lamb
Emeritus Professor John Kirby
| AlphaE integrin expression as a predictive biomarker for induction of clinical remission by etrolizumab: Analysis of a phase II trial in moderate-to-severely active ulcerative colitis | 2014 |
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Professor Chris Lamb
| Anti-TNF Withdrawal in IBD: Initial Results from a Pan-UK Study | 2014 |
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Stephen Douglass
Dr Annette Meeson
Dr Dorota Overbeck-Zubrzycka
Dr John Brain
Professor Chris Lamb
et al. | Breast cancer metastasis: demonstration that FOXP3 regulates CXCR4 expression and the response to CXCL12 | 2014 |
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Dr John Mansfield
Professor Chris Lamb
Emeritus Professor John Kirby
| Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial | 2014 |
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Professor Chris Lamb
Maria Price
Dr John Mansfield
| Faecal Calprotectin Is Useful In Predicting Long Term Disease Recurrence In Post-operative Crohn’s | 2014 |
|
Professor Chris Lamb
Dr John Mansfield
| The Impact Of NOD2 Variants on Gut Microbiota in Crohn’s Disease and Healthy Controls | 2014 |
|
Dr Carl Gamble
Professor Chris Lamb
Dr John Mansfield
| Thiopurine withdrawal during sustained clinical remission in inflammatory bowel disease: relapse and recapture rates, with predictive factors in 237 patients | 2014 |
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Professor Chris Lamb
Dr John Mansfield
Dr Graeme O'Boyle
Professor David Jones
Jennifer Kirby
et al. | Ulcerative colitis: The alpha E beta 7 integrin is associated with a high frequency of Th17, Th1 and Th17/Th1 CD4 lymphocytes | 2014 |
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Professor Chris Lamb
Dr John Mansfield
Dr Graeme O'Boyle
Professor David Jones
Dr Michael Keir
et al. | Ulcerative Colitis: The Alpha-e-beta-7 Integrin Is Associated With A High Frequency Of Th17, Th1 And Th17/th1 Cd4 Lymphocytes | 2014 |
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Professor Chris Lamb
Dr Lily Lamb
Dr John Mansfield
| Sexually transmitted infections manifesting as proctitis | 2013 |
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Professor Chris Lamb
Dr Graeme O'Boyle
Professor David Jones
Dr John Mansfield
Emeritus Professor John Kirby
et al. | Blockade of the B7 integrin prevents adherence of t lymphocytes to MAdCAM-1 in an in vitro model of vascular microcirculation post-capillary shear flow | 2012 |
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Dr Graeme O'Boyle
Christopher Fox
Dr Hannah Walden
Dr Joe Willet
Dr Emily Mavin
et al. | Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation | 2012 |
|
Professor Chris Lamb
| Developing an endoscopic mucosal resection service in a district general hospital | 2012 |
|
Professor Chris Lamb
| Rifaximin for recurrent hepatic encephalopathy following transjugular intrahepatic portosystemic shunt insertion | 2012 |
|
Professor Chris Lamb
Maria Price
Dr John Mansfield
| A real life retrospective analysis of drug expenditure reveals no significant cost difference between infliximab and adalimumab in the treatment of Adult Crohn's Disease | 2011 |
|
Professor Chris Lamb
| Gastroenterology 2010: Maximising patient care and safety while minimising unnecessary cost | 2011 |
|
Professor Chris Lamb
Mick Eltringham
| Generic medical and surgical endoscopy training lists can improve the number of opportunities for training in colonoscopy | 2011 |
|
Professor Chris Lamb
Dr John Mansfield
| Measurement of faecal calprotectin and lactoferrin in inflammatory bowel disease | 2011 |
|
Professor Chris Lamb
Maria Price
Professor David Jones
Dr John Mansfield
| Patients with Crohn's Disease report high levels of fatigue during a symptomatic disease flare | 2011 |
|
Professor Chris Lamb
Venkatesh Kanakala
Stephen Attwood
| Clinical lesson: eosinophilic oesophagitis, a new diagnosis to swallow | 2010 |
|
Dr Sohom Maitra
Professor Chris Lamb
Dr Andrew McLean-Tooke
Dr Gavin Spickett
Dr John Mansfield
et al. | Anti-tissue transglutaminase antibodies in the follow-up of adult coeliac disease | 2009 |
|
Professor Chris Lamb
Mohamed Mohiuddin
Fintan Bergin
Dr Jonathan Hanson
Dr John Mansfield
et al. | Faecal calprotectin or lactoferrin can identify postoperative recurrence in Crohn's disease | 2009 |
|
Professor Chris Lamb
Mohamed Mohiuddin
Fintan Bergin
Dr Jonathan Hanson
Dr John Mansfield
et al. | Longitudinal Study of Faecal Markers Following Ileal Resection in Crohn's Disease: Do Calprotectin and Lactoferrin Normalise Post Operatively? | 2009 |
|
Mohamed Mohiuddin
Professor Chris Lamb
Fintan Bergin
Dr Jonathan Hanson
Dr John Mansfield
et al. | Post Operative Crohn's Disease: The Role of Faecal Calprotectin and Lactoferrin in Assessing Disease Recurrence Following Ileal Resection | 2009 |
|
Stephen Attwood
Professor Chris Lamb
| Eosinophilic oesophagitis and other non-reflux inflammatory conditions of the oesophagus: Diagnostic imaging and management | 2008 |
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