Browse by author
Lookup NU author(s): Professor Tim Goodship
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
P>Atypical haemolytic uraemic syndrome (aHUS) is associated with a poor prognosis with regard to survival at presentation, recovery of renal function and transplantation. It is now established that aHUS is a disease of complement dysregulation with mutations in the genes encoding both complement regulators and activators, and autoantibodies against the complement regulator factor H. Identification of the underlying molecular abnormality in an individual patient can now help to guide their future management. In these guidelines we make recommendations for the investigation and management of aHUS patients both at presentation and in the long-term. We particularly address the role of renal transplantation alone and combined liver-kidney transplantation.
Author(s): Taylor CM, Machin S, Wigmore SJ, Goodship THJ, Renal Association, British Committee for Standards in Haematology, British Transplantation Society
Publication type: Article
Publication status: Published
Journal: British Journal of Haematology
ISSN (print): 0007-1048
ISSN (electronic): 1365-2141
Publisher: Wiley-Blackwell Publishing Ltd.
Altmetrics provided by Altmetric