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Lookup NU author(s): Professor Tim Goodship
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Results. Stenoses of both carotid arteries, left subclavian and vertebral arteries, several intracranial, right humeral, several coronary, and all pulmonary arteries were demonstrated. At the age of 13 years, left subclavian and right cervical carotid arteries were occluded. Right carotid recanalization induced intracranial dissection and death. The child had a Lys350Asp factor B mutation. Conclusion. Arterial steno-occlusive lesions appear as potential complications of dysregulated complement activation in aHUS. Endovascular treatment should be considered cautiously in this setting.
Author(s): Loirat C, Macher MA, Elmaleh-Berges M, Kwon T, Deschenes G, Goodship THJ, Majoie C, Davin JC, Blanc R, Savatovsky J, Moret J, Fremeaux-Bacchi V
Publication type: Article
Publication status: Published
Journal: Nephrology, Dialysis, Transplantation
Print publication date: 08/06/2010
ISSN (print): 0931-0509
ISSN (electronic): 1460-2385
Publisher: Oxford University Press
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