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Inflammatory myofibroblastic tumours of the respiratory tract: paediatric case series with varying clinical presentations

Lookup NU author(s): Dr Malcolm Brodlie, Dr Michael McKean, Andrew Welch


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Objectives: To highlight the clinical importance of inflammatory myofibroblastic tumours of the respiratory tract in children, and to present a case series of three children which illustrates this tumour's variable clinical presentation.Case history: The series includes: a nine-year-old girl with a diagnosis of juvenile idiopathic arthritis, who presented with finger clubbing and was found to have an inflammatory myofibroblastic tumour in her right upper lobe; a 15-year-old adolescent with a left main stem bronchial inflammatory myofibroblastic tumour, who presented with breathlessness and chest pain; and a 12-year-old girl with a tracheal inflammatory myofibroblastic tumour who presented with stridor. In each case, the tumour was resected surgically.Conclusion: Inflammatory myofibroblastic tumour are a rare but clinically important and pathologically distinct lesion of the respiratory tract in children. The cases in this series highlight some of the varied clinical presentations of inflammatory myofibroblastic tumours, and illustrate some of this tumour's different anatomical locations within the paediatric respiratory tract.

Publication metadata

Author(s): Brodlie M, Barwick SC, Wood KM, McKean MC, Welch A

Publication type: Article

Publication status: Published

Journal: Journal of Laryngology and Otology

Year: 2011

Volume: 125

Issue: 8

Pages: 865-868

Print publication date: 12/04/2011

ISSN (print): 0022-2151

ISSN (electronic): 1748-5460

Publisher: Cambridge University Press


DOI: 10.1017/S0022215111000648


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