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Domain-ligand mapping for enzymes

Lookup NU author(s): Dr Matthew BashtonORCiD

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Abstract

In this paper we provide an overview of our current knowledge of the mapping between small molecule ligands and protein domains. We give an overview of the present data resources available on the Web, which provide information about protein-ligand interactions, as well as discussing our own PROCOGNATE database. We present an update of ligand binding in large protein superfamilies and identify those ligands most frequently utilized by nature. Finally we discuss potential uses for this type of data.

Publication metadata

Author(s): Bashton M, Thornton M

Publication type: Article

Publication status: Published

Journal: Journal of Molecular Recognition

Year: 2010

Volume: 23

Issue: 2

Pages: 194-208

ISSN (print): 0952-3499

ISSN (electronic): 1099-1352

Publisher: John Wiley & Sons Ltd.

URL: http://dx.doi.org/10.1002/jmr.992

DOI: 10.1002/jmr.992

PubMed id: 19810051

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