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A sugar aminoacid for the development of multivalent ligands for Escherichia coli 0157 verotoxin

Lookup NU author(s): Professor Steve Homans

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Abstract

Functionalised carbohydrates for incorporation into multivalent ligands for the Escherichia coli 0157 verotoxin are highly desirable. Here, we report the synthesis of a sugar aminoacid based on the known Gal-α-1,4-Gal ligand for verotoxin in eight steps and in ∼10% overall yield.

Publication metadata

Author(s): Gibson D, Homans SW, Field RA

Publication type: Article

Publication status: Published

Journal: Tetrahedron: Asymmetry

Year: 2009

Volume: 20

Issue: 6-8

Pages: 730-732

ISSN (print): 0957-4166

ISSN (electronic): 1362-511X

Publisher: Pergamon

URL: http://dx.doi.org/10.1016/j.tetasy.2009.02.021

DOI: 10.1016/j.tetasy.2009.02.021

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