Publications by Professor Steve Homans - ePrints

Browsing publications by Professor Steve Homans.

Newcastle Authors	Title	Year
Professor Steve Homans	¹H, ¹⁵N and ¹³C backbone chemical shift assignment of titin domains A59-A60 and A60 alone	2014
Professor Steve Homans	Synthesis of uniformly deuterated n-dodecyl-β-d-maltoside (d₃₉-DDM) for solubilization of membrane proteins in TROSY NMR experiments	2014
Professor Steve Homans	TROSY NMR with a 52 kDa sugar transport protein and the binding of a small-molecule inhibitor	2014
Professor Steve Homans	¹H, ¹⁵N and ¹³C backbone chemical shift assignment of the titin A67-A68 domain tandem	2012
Professor Steve Homans Liang Luo	NMR methods for structure-function investigation of membrane proteins and their ligands	2012
Professor Steve Homans	Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid	2012
Professor Steve Homans	Conformational Conversion during Amyloid Formation at Atomic Resolution	2011
Professor Steve Homans	Ligand binding to distinct states diverts aggregation of an amyloid-forming protein	2011
Dr Agnieszka Bronowska Professor Steve Homans	Comparison of Entropic Contributions to Binding in a "Hydrophilic" versus "Hydrophobic" Ligand-Protein Interaction	2010
Professor Steve Homans	A sugar aminoacid for the development of multivalent ligands for Escherichia coli 0157 verotoxin	2009
Professor Steve Homans	Amyloid fibril length distribution quantified by atomic force microscopy single-particle image analysis	2009
Professor Steve Homans	Fibril Fragmentation Enhances Amyloid Cytotoxicity	2009
Professor Steve Homans	Poxvirus K7 Protein Adopts a Bcl-2 Fold: Biochemical Mapping of Its Interactions with Human DEAD Box RNA Helicase DDX3	2009
Professor Steve Homans	Probing Dynamics within Amyloid Fibrils Using a Novel Capping Method	2009
Professor Steve Homans	Synthesis of prospective disaccharide ligands for Escherichia coli O157 verotoxin	2009
Professor Steve Homans	Fibril growth kinetics reveal a region of beta(2)-microglobulin important for nucleation and elongation of aggregation	2008
Professor Steve Homans	Perspectives on NMR in drug discovery: a technique comes of age	2008
Dr Agnieszka Bronowska Professor Steve Homans	Residual Ligand Entropy in the Binding of p-Substituted Benzenesulfonamide Ligands to Bovine Carbonic Anhydrase II	2008
Professor Steve Homans	RNA packing specificity and folding during assembly of the bacteriophage MS2	2008
Professor Steve Homans	Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly	2008
Professor Steve Homans	A simple, RNA-mediated allosteric switch controls the pathway to formation of a T=3 viral capsid	2007
Professor Steve Homans	Dynamics and thermodynamics of ligand-protein interactions	2007
Professor Steve Homans	Evidence of chemical exchange in recombinant Major Urinary Protein and quenching thereof upon pheromone binding	2007
Dr Agnieszka Bronowska Professor Steve Homans	Global changes in local protein dynamics reduce the entropic cost of carbohydrate binding in the arabinose-binding protein	2007
Professor Steve Homans	Hadamard NMR spectroscopy for relaxation measurements of large (>35 kDa) proteins	2007
Professor Steve Homans	Origin of heat capacity changes in a "Nonclassical" hydrophobic interaction	2007
Professor Steve Homans	Water, water everywhere--except where it matters?	2007
Professor Steve Homans	Amyloid formation under physiological conditions proceeds via a native-like folding intermediate	2006
Dr Agnieszka Bronowska Professor Steve Homans	Contribution of ligand desolvation to binding thermodynamics in a ligand-protein interaction	2006
Dr Agnieszka Bronowska Professor Steve Homans	Thermodynamic penalty arising from burial of a ligand polar group within a hydrophobic pocket of a protein receptor	2006
Professor Steve Homans	Dissecting the fine details of assembly of a T=3 capsid	2005
Professor Steve Homans	Dynamics in the unfolded state of beta(2)-microglobulin studied by NMR	2005
Professor Steve Homans	Effects of protein-pheromone complexation on correlated chemical shift modulations	2005
Professor Steve Homans	Probing the binding entropy of ligand-protein interactions by NMR	2005
Professor Steve Homans	Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex	2005
Professor Steve Homans	Van der Waals interactions dominate ligand-protein association in a protein binding site occluded from solvent water	2005
Professor Steve Homans	Backbone resonance assignment of the L-arabinose binding protein in complex with D-galactose	2004
Professor Steve Homans	Dissecting the cholera toxin-ganglioside GM1 interaction by isothermal titration calorimetry	2004
Professor Steve Homans Dr Achim Treumann	Identification of the 5-Methylthiopentosyl Substituent in Mycobacterium tuberculosis Lipoarabinomannan	2004
Professor Steve Homans	NMR spectroscopy tools for structure-aided drug design	2004
Professor Steve Homans	Thermodynamics of binding of 2-methoxy-3-isopropylpyrazine and 2-methoxy-3-isobutylpyrazine to the major urinary protein	2004
Professor Steve Homans	Thermodynamics of binding of D-galactose and deoxy derivatives thereof to the L-arabinose-binding protein	2004
Professor Steve Homans	Determinants of pH sensing folds using backbone residual dipolar coupling and long range NOE restraints	2003
Professor Steve Homans	Large-scale millisecond intersubunit dynamics in the B subunit homopentamer of the toxin derived from Escherichia coli O157	2003
Professor Steve Homans	Methyl side-chain dynamics in proteins using selective enrichment with a single isotopomer	2003
Professor Steve Homans	Optimization of tether length in nonglycosidically linked bivalent ligands that target sites 2 and 1 of a Shiga-like toxin	2003
Professor Steve Homans	1H-filtered correlation experiments for assignment and determination of coupling constants in backbone labelled proteins	2002
Dr Achim Treumann Professor Steve Homans	5-methylthiopentose: a new substituent on lipoarabinomannan in Mycobacterium tuberculosis	2002
Professor Steve Homans	Binding and computer modeling studies of non-glycosidically tethered bivalent ligands for Shiga-like toxin type 1	2002
Professor Steve Homans	Structural analysis of Vma7p, subunit F of the vacuolar H+ATPase	2002
Professor Steve Homans	Structural properties of an amyloid precursor ofβ2-microglobulin	2002
Professor Steve Homans	Measurement of one-bond 1H-13C, couplings in backbone-labelled proteins	2001
Professor Steve Homans	Multi-dimensional nuclear magnetic resonance studies of the dynamics and mechanism of class II fructose-1,6-bisphosphate aldolase	2001
Professor Steve Homans	Residual 2H Quadrupolar couplings in weakly aligned carbohydrates	2001
Professor Steve Homans	Localization of the binding site for the oligosaccharide moiety of Gb3 on verotoxin 1 using NMR residual dipolar coupling measurements	2000
Professor Steve Homans	Structural analysis of the transforming growth factor beta receptor II: The fast track NMR approach	2000
Professor Steve Homans	Derivation of the Bound-State Conformation of a Ligand in a Weakly Aligned Ligand-Protein Complex	1999
Professor Steve Homans	Improved Resolution and Sensitivity of Triple-Resonance NMR Methods for the Structural Analysis of Proteins by Use of a Backbone-Labeling Strategy	1999
Professor Steve Homans	Stable-Isotope-Assisted NMR Studies on 13C-Enriched Sialyl Lewisx in Solution and Bound to E-Selectin	1999
Professor Steve Homans	Structure of the Phosphosaccharide-Inositol Core of the Leishmania-Donovani Lipophosphoglycan	1989