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Browsing publications by Professor Steve Homans.

Newcastle AuthorsTitleYearFull text
Professor Steve Homans
1H, 15N and 13C backbone chemical shift assignment of titin domains A59-A60 and A60 alone2014
Professor Steve Homans
Synthesis of uniformly deuterated n-dodecyl-β-d-maltoside (d39-DDM) for solubilization of membrane proteins in TROSY NMR experiments2014
Professor Steve Homans
TROSY NMR with a 52 kDa sugar transport protein and the binding of a small-molecule inhibitor2014
Professor Steve Homans
¹H, ¹⁵N and ¹³C backbone chemical shift assignment of the titin A67-A68 domain tandem2012
Professor Steve Homans
Liang Luo
NMR methods for structure-function investigation of membrane proteins and their ligands2012
Professor Steve Homans
Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid2012
Professor Steve Homans
Conformational Conversion during Amyloid Formation at Atomic Resolution2011
Professor Steve Homans
Ligand binding to distinct states diverts aggregation of an amyloid-forming protein2011
Dr Agnieszka Bronowska
Professor Steve Homans
Comparison of Entropic Contributions to Binding in a "Hydrophilic" versus "Hydrophobic" Ligand-Protein Interaction2010
Professor Steve Homans
A sugar aminoacid for the development of multivalent ligands for Escherichia coli 0157 verotoxin2009
Professor Steve Homans
Amyloid fibril length distribution quantified by atomic force microscopy single-particle image analysis2009
Professor Steve Homans
Fibril Fragmentation Enhances Amyloid Cytotoxicity2009
Professor Steve Homans
Poxvirus K7 Protein Adopts a Bcl-2 Fold: Biochemical Mapping of Its Interactions with Human DEAD Box RNA Helicase DDX32009
Professor Steve Homans
Probing Dynamics within Amyloid Fibrils Using a Novel Capping Method2009
Professor Steve Homans
Synthesis of prospective disaccharide ligands for Escherichia coli O157 verotoxin2009
Professor Steve Homans
Fibril growth kinetics reveal a region of beta(2)-microglobulin important for nucleation and elongation of aggregation2008
Professor Steve Homans
Perspectives on NMR in drug discovery: a technique comes of age2008
Dr Agnieszka Bronowska
Professor Steve Homans
Residual Ligand Entropy in the Binding of p-Substituted Benzenesulfonamide Ligands to Bovine Carbonic Anhydrase II2008
Professor Steve Homans
RNA packing specificity and folding during assembly of the bacteriophage MS22008
Professor Steve Homans
Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly2008
Professor Steve Homans
A simple, RNA-mediated allosteric switch controls the pathway to formation of a T=3 viral capsid2007
Professor Steve Homans
Dynamics and thermodynamics of ligand-protein interactions2007
Professor Steve Homans
Evidence of chemical exchange in recombinant Major Urinary Protein and quenching thereof upon pheromone binding2007
Dr Agnieszka Bronowska
Professor Steve Homans
Global changes in local protein dynamics reduce the entropic cost of carbohydrate binding in the arabinose-binding protein2007
Professor Steve Homans
Hadamard NMR spectroscopy for relaxation measurements of large (>35 kDa) proteins2007
Professor Steve Homans
Origin of heat capacity changes in a "Nonclassical" hydrophobic interaction2007
Professor Steve Homans
Water, water everywhere--except where it matters?2007
Professor Steve Homans
Amyloid formation under physiological conditions proceeds via a native-like folding intermediate2006
Dr Agnieszka Bronowska
Professor Steve Homans
Contribution of ligand desolvation to binding thermodynamics in a ligand-protein interaction2006
Dr Agnieszka Bronowska
Professor Steve Homans
Thermodynamic penalty arising from burial of a ligand polar group within a hydrophobic pocket of a protein receptor2006
Professor Steve Homans
Dissecting the fine details of assembly of a T=3 capsid2005
Professor Steve Homans
Dynamics in the unfolded state of beta(2)-microglobulin studied by NMR2005
Professor Steve Homans
Effects of protein-pheromone complexation on correlated chemical shift modulations2005
Professor Steve Homans
Probing the binding entropy of ligand-protein interactions by NMR2005
Professor Steve Homans
Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex2005
Professor Steve Homans
Van der Waals interactions dominate ligand-protein association in a protein binding site occluded from solvent water2005
Professor Steve Homans
Backbone resonance assignment of the L-arabinose binding protein in complex with D-galactose2004
Professor Steve Homans
Dissecting the cholera toxin-ganglioside GM1 interaction by isothermal titration calorimetry2004
Professor Steve Homans
Dr Achim Treumann
Identification of the 5-Methylthiopentosyl Substituent in Mycobacterium tuberculosis Lipoarabinomannan2004
Professor Steve Homans
NMR spectroscopy tools for structure-aided drug design2004
Professor Steve Homans
Thermodynamics of binding of 2-methoxy-3-isopropylpyrazine and 2-methoxy-3-isobutylpyrazine to the major urinary protein2004
Professor Steve Homans
Thermodynamics of binding of D-galactose and deoxy derivatives thereof to the L-arabinose-binding protein2004
Professor Steve Homans
Determinants of pH sensing folds using backbone residual dipolar coupling and long range NOE restraints2003
Professor Steve Homans
Large-scale millisecond intersubunit dynamics in the B subunit homopentamer of the toxin derived from Escherichia coli O1572003
Professor Steve Homans
Methyl side-chain dynamics in proteins using selective enrichment with a single isotopomer2003
Professor Steve Homans
Optimization of tether length in nonglycosidically linked bivalent ligands that target sites 2 and 1 of a Shiga-like toxin2003
Professor Steve Homans
1H-filtered correlation experiments for assignment and determination of coupling constants in backbone labelled proteins2002
Dr Achim Treumann
Professor Steve Homans
5-methylthiopentose: a new substituent on lipoarabinomannan in Mycobacterium tuberculosis2002
Professor Steve Homans
Binding and computer modeling studies of non-glycosidically tethered bivalent ligands for Shiga-like toxin type 12002
Professor Steve Homans
Structural analysis of Vma7p, subunit F of the vacuolar H+ATPase2002
Professor Steve Homans
Structural properties of an amyloid precursor ofβ2-microglobulin2002
Professor Steve Homans
Measurement of one-bond 1H-13C, couplings in backbone-labelled proteins2001
Professor Steve Homans
Multi-dimensional nuclear magnetic resonance studies of the dynamics and mechanism of class II fructose-1,6-bisphosphate aldolase2001
Professor Steve Homans
Residual 2H Quadrupolar couplings in weakly aligned carbohydrates2001
Professor Steve Homans
Localization of the binding site for the oligosaccharide moiety of Gb3 on verotoxin 1 using NMR residual dipolar coupling measurements2000
Professor Steve Homans
Structural analysis of the transforming growth factor beta receptor II: The fast track NMR approach2000
Professor Steve Homans
Derivation of the Bound-State Conformation of a Ligand in a Weakly Aligned Ligand-Protein Complex1999
Professor Steve Homans
Improved Resolution and Sensitivity of Triple-Resonance NMR Methods for the Structural Analysis of Proteins by Use of a Backbone-Labeling Strategy1999
Professor Steve Homans
Stable-Isotope-Assisted NMR Studies on 13C-Enriched Sialyl Lewisx in Solution and Bound to E-Selectin1999
Professor Steve Homans
Structure of the Phosphosaccharide-Inositol Core of the Leishmania-Donovani Lipophosphoglycan1989