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New conduction abnormalities after TAVI-frequency and causes

Lookup NU author(s): Professor Bob Anderson


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Transcatheter aortic valve implantation (TAVI) is increasingly used to treat patients with aortic stenosis who are considered to be too high-risk for surgical replacement of the aortic valve. Although the procedural risks are decreasing, the occurrence of new conduction abnormalities remains a vexing issue. Both left bundle branch block and atrioventricular dissociation can affect prognosis after TAVI. Understanding the intimate relationship between the atrioventricular conduction axis and the aortic root, in addition to elucidation of factors related specifically to the procedure, devices, and patients, might help to reduce these conduction abnormalities. The purpose of this Review is to assess, and offer insights into, the available information on the frequency of new conduction abnormalities associated with TAVI, their anatomical and procedural causes, and their clinical consequences.

Publication metadata

Author(s): van der Boon RM, Nuis RJ, Van Mieghem NM, Jordaens L, Rodes-Cabau J, van Domburg RT, Serruys PW, Anderson RH, de Jaegere PPT

Publication type: Review

Publication status: Published

Journal: Nature Reviews Cardiology

Year: 2012

Volume: 9

Issue: 8

Pages: 454-463

Print publication date: 01/08/2012

ISSN (print): 1759-5002

ISSN (electronic): 1759-5010



DOI: 10.1038/nrcardio.2012.58