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Genomic Analysis Drives Tailored Therapy in Poor Risk Childhood Leukemia

Lookup NU author(s): Professor Christine Harrison FRCPath FMedSci

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Abstract

Ph-like acute lymphoblastic leukemia (ALL) is a novel subgroup of high-risk childhood ALL. In this issue of Cancer Cell, Roberts et al. describe the identification of genetic alterations that lead to activated kinase and cytokine receptor signaling in Ph-like ALL and demonstrate that this aberrant signaling can be inhibited effectively.

Publication metadata

Author(s): Harrison CJ

Publication type: Editorial

Publication status: Published

Journal: Cancer Cell

Year: 2012

Volume: 22

Issue: 2

Pages: 139-140

Print publication date: 14/08/2012

ISSN (print): 1535-6108

ISSN (electronic): 1878-3686

Publisher: Cell Press

URL: http://dx.doi.org/10.1016/j.ccr.2012.07.012

DOI: 10.1016/j.ccr.2012.07.012

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