Publications by Professor Christine Harrison FRCPath FMedSci - ePrints

Browsing publications by Professor Christine Harrison FRCPath FMedSci.

Newcastle Authors	Title	Year
Professor Christine Harrison FRCPath FMedSci	Optimized cytogenetic risk-group stratification of KMT2A-rearranged pediatric acute myeloid leukemia	2024
Ellie Butler Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Clinical characteristics and outcomes of B-cell precursor ALL with MEF2D rearrangements: a retrospective study by the Ponte di Legno Childhood ALL Working Group	2023
Dr Paul Sinclair Dr Ruth Cranston Prahlad Raninga Joanna Cheng Rebecca Hanna et al.	Disruption to the FOXO-PRDM1 axis resulting from deletions of chromosome 6 in acute lymphoblastic leukaemia	2023
Sarra Ryan Claire Schwab Dr Richard Yim Dr Ruth Cranston Dr Lisa Russell et al.	Whole genome sequencing provides comprehensive genetic testing in childhood B-cell acute lymphoblastic leukaemia	2023
Dr Deepali Pal Dr Helen Blair Sean Hockney Dr Melanie Beckett Mankaran Singh et al.	hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia	2022
Dr Carmela Ciardullo Dr Katarzyna Szoltysek Dr Peixun Zhou Dr Elaine Willmore Dr Amir Enshaei et al.	Low BACH2 expression predicts adverse outcome in chronic lymphocytic leukaemia	2022
Professor Anthony Moorman Dr Grace Antony Ellie Butler Dr Amir Enshaei Professor Christine Harrison FRCPath FMedSci et al.	Time to Cure for Childhood and Young Adult Acute Lymphoblastic Leukemia Is Independent of Early Risk Factors: Long-Term Follow-Up of the UKALL2003 Trial	2022
Ellie Butler Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Clinical characteristics and outcomes of B-ALL with ZNF384 rearrangements: a retrospective analysis by the Ponte di Legno Childhood ALL Working Group	2021
Professor Christine Harrison FRCPath FMedSci	Cytogenetics of pediatric acute myeloid leukemia: A review of the current knowledge	2021
Claire Schwab Professor Christine Harrison FRCPath FMedSci	Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study	2021
Professor Christine Harrison FRCPath FMedSci	Prevention of childhood leukaemia by lifestyle changes	2021
Dr Amir Enshaei Professor Christine Harrison FRCPath FMedSci Claire Schwab Professor Anthony Moorman	A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia	2020
Professor Anthony Moorman Claire Schwab Emily Winterman Dr Frederik van Delft Professor Christine Harrison FRCPath FMedSci et al.	Adjuvant tyrosine kinase inhibitor therapy improves outcome for children and adolescents with acute lymphoblastic leukaemia who have an ABL-class fusion	2020
Dr Matthew Bashton Robin Hollis Dr Sarra Ryan Claire Schwab Professor Christine Harrison FRCPath FMedSci et al.	Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia	2020
Dr Katarzyna Szoltysek Dr Carmela Ciardullo Dr Peixun Zhou Dr Anna Walaszczyk Dr Elaine Willmore et al.	Dap kinase-related apoptosis-inducing protein kinase 2 (Drak2) is a key regulator and molecular marker in chronic lymphocytic leukemia	2020
Claire Schwab Professor Christine Harrison FRCPath FMedSci	Design of a Comprehensive Fluorescence in Situ Hybridization Assay for Genetic Classification of T-Cell Acute Lymphoblastic Leukemia	2020
Professor Christine Harrison FRCPath FMedSci	MLPA and DNA index improve the molecular diagnosis of childhood B-cell acute lymphoblastic leukemia	2020
Dr Matthew Bashton Professor Christine Harrison FRCPath FMedSci	IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia	2019
Professor James Allan Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Author correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia	2019
Alex Newman Dr Masood Zaka Dr Peixun Zhou Dr Amy Erhorn Amy Barnard et al.	Biallelic Inactivation of TP53 is Associated with an Increased Risk of Relapse in Paediatric B-Cell Non-Hodgkin Lymphoma(B-NHL)	2019
Claire Schwab Professor Christine Harrison FRCPath FMedSci	Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia	2019
Dr Paul Sinclair Dr Sarra Ryan Dr Matthew Bashton Shaun Hollern Rebecca Hanna et al.	SH2B3 inactivation through CN-LOH-12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain	2019
Dr Helen Blair Professor Christine Harrison FRCPath FMedSci Dr Lisa Russell	Single cell analysis identifies CRLF2 rearrangements as both early and late events in Down syndrome and non-Down syndrome acute lymphoblastic leukaemia	2019
Dr Tom Creasey Dr Amir Enshaei Kathryn Watts Gavin Cuthbert Claire Schwab et al.	Single Nucleotide Polymorphism Array-Based Signature of Genetic Ploidy Groups in Acute Lymphoblastic Leukemia	2019
Dr Lina Hamadeh Dr Amir Enshaei Claire Schwab Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman et al.	Validation of the United Kingdom copy-number alteration classifier in 3239 children with B-cell precursor ALL	2019
Dr Ruth Cranston Dr Paul Sinclair Dr Matthew Bashton Dr Matthew Selby Professor Christine Harrison FRCPath FMedSci et al.	A Genome-Wide CRISPR Screen Implicates MYC Dysregulation in TCF3-PBX1 B-ALL	2018
Alex Newman Dr Masood Zaka Dr Peixun Zhou Dr Amy Erhorn Dr Rachel Crossland et al.	Biallelic inactivation of TP53 is associated with an increased risk of relapse in paediatric B-cell non-Hodgkin lymphoma (B-NHL)	2018
Dr Paul Sinclair Dr Helen Blair Dr Sarra Ryan Dr Lars Buechler Joanna Cheng et al.	Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21	2018
Professor James Allan Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia	2018
Alex Newman Dr Peixun Zhou Dr Masood Zaka Professor Christine Harrison FRCPath FMedSci Dr Simon Bomken et al.	Genomic landscape of adult and paediatric B-cell Non-Hodgkin lymphoma	2018
Professor Christine Harrison FRCPath FMedSci Dr Simona Constantinescu	Mutant JAK3 signaling is increased by loss of wild-type JAK3 or by acquisition of secondary JAK3 mutations in T-ALL	2018
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL	2018
Dr Luca Ermini Dr Frederik van Delft Dr Sarah Jenkinson Professor Christine Harrison FRCPath FMedSci	The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia	2018
Claire Schwab Professor Christine Harrison FRCPath FMedSci	The T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling	2018
Professor Anthony Moorman Professor Julie Irving Professor James Allan Professor Christine Harrison FRCPath FMedSci	A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1	2017
Dr Britta Vormoor Professor Gareth Veal Melanie Griffin Professor Julie Irving Lynne Minto et al.	A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia	2017
Dr Lucy Chilton Professor Christine Harrison FRCPath FMedSci Daniel Murdy Professor Anthony Moorman	Clinical relevance of failed and missing cytogenetic analysis in acute myeloid leukaemia	2017
Zach Dixon Dr Lindsay Nicholson Elizabeth Matheson Dr Paul Sinclair Professor Christine Harrison FRCPath FMedSci et al.	CREBBP knockdown enhances RAS/RAF/MEK/ERK signaling in Ras pathway mutated acute lymphoblastic leukemia but does not modulate chemotherapeutic response	2017
Claire Schwab Professor Christine Harrison FRCPath FMedSci	Digital Multiplex Ligation-Dependent Probe Amplification for Detection of Key Copy Number Alterations in T- and B-Cell Lymphoblastic Leukemia	2017
Dr Amir Enshaei Professor Christine Harrison FRCPath FMedSci Dr Sujith Samarasinghe Claire Schwab Professor Anthony Moorman et al.	Genotype-Specific Minimal Residual Disease Interpretation Improves Stratification in Pediatric Acute Lymphoblastic Leukemia	2017
Claire Schwab Dr Lucy Chilton Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Intragenic amplification of PAX5: a novel subgroup in B-cell precursor acute lymphoblastic leukemia?	2017
Professor Christine Harrison FRCPath FMedSci	Unlocking the potential of anti-CD33 therapy in adult and childhood acute myeloid leukemia	2017
Professor Anthony Moorman Claire Schwab Professor Christine Harrison FRCPath FMedSci Dr Sujith Samarasinghe	Use of minimal residual disease assessment to redefine induction failure in pediatric acute lymphoblastic leukemia	2017
Claire Schwab Sarra Ryan Dr Lucy Chilton Alannah Elliott James Murray et al.	EBF1-PDGFRB fusion in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL): genetic profile and clinical implications	2016
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Acute lymphoblastic leukaemia	2016
Dr Carmela Ciardullo Dr Elaine Willmore Dr Amir Enshaei Dr Peixun Zhou Dr Vikki Rand et al.	BACH2 and BCL6 Cooperatively Fuction as Tumour Suppressors in CLL	2016
Dr Lisa Russell Lisa Jones Dr Amir Enshaei Dr Stefano Tonin Sarra Ryan et al.	Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia	2016
Professor Christine Harrison FRCPath FMedSci	Chronic Myeloid Leukemia: Reminiscences And Dreams	2016
Professor Christine Harrison FRCPath FMedSci Claire Schwab	Constitutional abnormalities of chromosome 21 predispose to iAMP21-acute lymphoblastic leukaemia	2016
Claire Schwab Professor Christine Harrison FRCPath FMedSci	Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia	2016
Claire Schwab Professor Christine Harrison FRCPath FMedSci	Genetic characterization and therapeutic targeting of MYC translocated pediatric T-cell acute lymphoblastic leukemia	2016
Dr Carmela Ciardullo Dr Elaine Willmore Dr Peixun Zhou Dr Vikki Rand Professor Christine Harrison FRCPath FMedSci et al.	Impact of the apoptotic regulator DRAK2 in chronic lymphocytic leukemia	2016
Dr Carmela Ciardullo Dr Peixun Zhou Dr Elaine Willmore Professor Christine Harrison FRCPath FMedSci Dr Andrew Hall et al.	Impact of the apoptotic regulator DRAK2 in chronic lymphocytic leukemia	2016
Professor Julie Irving Dr Amir Enshaei Dr Amy Erhorn Lynne Minto Claire Schwab et al.	Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukaemia	2016
Dr Lucy Chilton Professor Christine Harrison FRCPath FMedSci	The prognostic significance of trisomy 4 in acute myeloid leukaemia is dependent on age and additional abnormalities	2016
Dr Sarra Ryan Elizabeth Matheson Dr Paul Sinclair Dr Matthew Bashton Claire Schwab et al.	The role of the RAS pathway in iAMP21-ALL	2016
Professor Christine Harrison FRCPath FMedSci	Blood Spotlight on iAMP21 acute lymphoblastic leukemia (ALL), a high-risk pediatric disease	2015
Dr Mark Wade Dr Nicola Sunter Dr Sarah Fordham Anna Long Dino Mašić et al.	c-MYC is a radiosensitive locus in human breast cells	2015
Dr Paul Sinclair Joanna Cheng Prahlad Raninga Rebecca Hanna Shaun Hollern et al.	A Targeted Functional Clone Tracking Assay for the Identification of Tumour Suppressor Genes in BCP- ALL Implicates the Transcription Factors FOXO3 and PRDM1	2015
Professor Christine Harrison FRCPath FMedSci	Acute lymphoblastic leukemia	2015
Professor Christine Harrison FRCPath FMedSci	Acute myeloid leukemia	2015
Professor Christine Harrison FRCPath FMedSci	Advances in the Genetics of Childhood Leukaemia: a Success Story	2015
Dr Al Gabriel Dr Amir Enshaei Jennifer Taylor Dr Amy Erhorn Claire Schwab et al.	Age specific incidence of partner gene and secondary abnormalities in MLL positive acute lymphoblastic leukaemia (ALL)	2015
Dr Lisa Russell Lisa Jones Dr Amir Enshaei Jamie Rutherford Dr Stefano Tonin et al.	Clincial and Genetic Landscapes Differ Between IGH-CRLF2 and P2RY8-CRLF2 Acute Lymphoblastic Leukaemia	2015
Dr Lisa Russell Lisa Jones Dr Amir Enshaei Dr Stefano Tonin Dr Sarra Ryan et al.	Clincial and Genetic Landscapes Differ Between IGH-CRLF2 and P2RY8-CRLF2 Acute Lymphoblastic Leukaemia	2015
Professor Christine Harrison FRCPath FMedSci	Clinical Impact of Additional Cytogenetic Aberrations, cKIT and RAS Mutations, and Treatment Elements in Pediatric t(8;21)-AML: Results From an International Retrospective Study by the International Berlin-Frankfurt-Munster Study Group	2015
Professor Anthony Moorman Professor Julie Irving Dr Amir Enshaei Dr Amy Erhorn Lynne Minto et al.	Composite Index for Risk Prediction in Relapsed Childhood Acute Lymphoblastic Leukaemia	2015
Dr Al Gabriel Fadhel Alsaid Naji Dr Ed Schwalbe Dr Sirintra Nakjang Dr Simon Cockell et al.	Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia	2015
Dr Dino Masic Dr Amir Enshaei Lisa Jones Professor Christine Harrison FRCPath FMedSci Dr Lisa Russell et al.	Genetic Characterisation of Immunoglobulin Heavy Chain Locus CCAAT Enhancer-Binding Protein Translocated Acute Lymphoblastic Leukaemia	2015
Dino Mašić Dr Amir Enshaei Lisa Jones Professor Christine Harrison FRCPath FMedSci Dr Lisa Russell et al.	Genetic Characterisation of Immunoglobulin Heavy Chain Locus CCAAT Enhancer-Binding Protein Translocated Acute Lymphoblastic Leukaemia	2015
Dr Amir Enshaei Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci Dr Sujith Samarasinghe	Integration of Minimal Residual Disease with Other Patient Risk Factors Identifies a Population with Very Poor Overall Survival in Pediatric ALL: Results from the UKALL 2003 Trial	2015
Dr Amir Enshaei Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci Dr Sujith Samarasinghe	Long Term Overall Survival of Greater Than 98% in Childhood ALL Patients with Good Risk Features and Low Risk MRD: Results from a Large Multi-Center Randomized Controlled Trial, UKALL 2003	2015
Dr Amir Enshaei Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci Dr Sujith Samarasinghe	Long Term Overall Survival of Greater Than 98% in Childhood ALL Patients with Good Risk Features and Low Risk MRD:A Results from a Large Multi-Center Randomized Controlled Trial, UKALL 2003	2015
Dr Lucy Chilton Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Prognostic Significance and Risk Stratification in Acute Myeloid Leukaemia Patients in the Absence of Successful Cytogenetic Analysis	2015
Dr Lindsay Nicholson Elizabeth Matheson Lynne Minto Christopher Keilty Maryna Sanichar et al.	Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition	2015
Professor Julie Irving Elizabeth Matheson Helen Blair Marian Case Isabella Swidenbank et al.	Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition. Blood. 2014;124(23):3420-3430	2015
Professor Christine Harrison FRCPath FMedSci	Refinement of IKZF1 status in pediatric Philadelphia-positive acute lymphoblastic leukemia	2015
Dr Amir Enshaei Claire Schwab Dr Lucy Chilton Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman et al.	Risk Factor Analysis in Paediatric Acute Lymphoblastic Leukaemia with High Hyperdiploidy	2015
Claire Schwab Alannah Elliott Dr Lucy Chilton Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci et al.	Targeted Sequencing Identifies Association Between IL7R-JAK Mutations And Epigenetic Modulators In T-Cell Acute Lymphoblastic Leukemia.	2015
Professor Anthony Moorman Professor Julie Irving Professor James Allan Professor Christine Harrison FRCPath FMedSci	The 9p21.3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN2A	2015
Dr Jeyanthy Eswaran Dr Paul Sinclair Professor Olaf Heidenreich Professor Julie Irving Dr Lisa Russell et al.	The pre-B-cell receptor checkpoint in acute lymphoblastic leukaemia	2015
Claire Schwab Professor Christine Harrison FRCPath FMedSci	ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling	2015
Dr Lisa Russell Dr Amir Enshaei Lisa Jones Dr Amy Erhorn Dr Dino Masic et al.	IGH@ Translocations Are Prevalent in Teenagers and Young Adults With Acute Lymphoblastic Leukemia and Are Associated With a Poor Outcome	2014
Lisa Jones Professor Christine Harrison FRCPath FMedSci Dr Lisa Russell	IGH@ Translocations Co-exist With Other Primary Rearrangements in B-cell Precursor Acute Lymphoblastic Leukemia	2014
Professor Christine Harrison FRCPath FMedSci	IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL	2014
Professor Anthony Moorman Dr Amir Enshaei Claire Schwab Dr Lucy Chilton Alannah Elliott et al.	A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia	2014
Professor Christine Harrison FRCPath FMedSci	Clinical Impact of Additional Cytogenetic Aberrations, cKIT- and RAS Mutations and Other Factors in Pediatric t(8;21)-AML	2014
Claire Schwab Professor Christine Harrison FRCPath FMedSci	CMYC-translocations in t-cell acute lymphoblastic leukemia	2014
Claire Schwab Sarra Ryan Professor Anthony Moorman Dr Richard McNally Professor Bryan Young et al.	Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia	2014
Claire Schwab Dr Sarra Ryan Professor Christine Harrison FRCPath FMedSci	Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia	2014
Claire Schwab Becca Andrews Dr Lucy Chilton Alannah Elliott Gerald Keil et al.	EBF1-PDGFRB Fusion in Paediatric Acute Lymphoblastic Leukaemia (ALL): Genetic Profile and Clinical Implications	2014
Claire Schwab Professor Christine Harrison FRCPath FMedSci	Genetic profile of T-cell acute lymphoblastic leukemias with MYC translocations	2014
Dr Lucy Chilton Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	High hyperdiploidy among adolescents and adults with acute lymphoblastic leukaemia (ALL): cytogenetic features, clinical characteristics and outcome	2014
Dr Lucy Chilton Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Hyperdiploidy with 49-65 chromosomes represents a heterogeneous cytogenetic subgroup of acute myeloid leukemia with differential outcome.	2014
Dr Jeyanthy Eswaran Dr Paul Sinclair Dr Sirintra Nakjang Professor Christine Harrison FRCPath FMedSci	Identification of Cmtm Family Proteins As Tumor Suppressor and Membrane Regulator in B Cell Precursor Acute Lymphoblastic Leukemia	2014
Professor Christine Harrison FRCPath FMedSci	No chromosome arm unturned: in memory of Roland Berger 1934-2012	2014
Jake Clayton Joanna Cheng Dr Sarra Ryan Professor Christine Harrison FRCPath FMedSci Dr Paul Sinclair et al.	Oncogenomic Screening Strategies to Identify Tumour Suppressor Genes on Chromosome 12 in Acute Myeloid Leukaemia	2014
Professor Julie Irving Elizabeth Matheson Dr Helen Blair Marian Case Isabella Swidenbank et al.	Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition	2014
Professor Christine Harrison FRCPath FMedSci Claire Schwab	Refinement of IKZF1 Genomic Status in Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia	2014
Claire Schwab Becca Andrews Dr Lucy Chilton Alannah Elliott Dr Stacey Richardson et al.	SSBP2-CSF1R Is a Recurrent Fusion in B-Other Acute Lymphoblastic Leukaemia with Variable Clinical Outcome	2014
Alannah Elliott Dr Lucy Chilton Professor Christine Harrison FRCPath FMedSci	Targeted resequencing of 115 genes identifies association between jak3 and epigenetic mutations in t-cell acute lymphoblastic leukemia	2014
Dr Frederik van Delft Professor Christine Harrison FRCPath FMedSci	The Sub-Clonal Complexity of STIL-TAL1 T-ALL	2014
Claire Schwab Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	BTG1 deletions do not predict outcome in Down syndrome acute lymphoblastic leukemia	2013
Dr Halima Al-shehhi Claire Schwab Dr Amy Erhorn Dr Al Gabriel Professor Christine Harrison FRCPath FMedSci et al.	Abnormalities of the der(12)t(12;21) in ETV6-RUNX1 acute lymphoblastic leukemia	2013
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman Claire Schwab Dr Lucy Chilton	An international study of intrachromosomal amplification of chromosome 21 (iAMP21): cytogenetic characterization and outcome	2013
Claire Schwab Dr Lucy Chilton Heather Morrison Lisa Jones Dr Halima Al-shehhi et al.	Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features	2013
Professor Christine Harrison FRCPath FMedSci	IKZF1 Deletions Predict Relapse in BCR-ABL1-Positive Childhood Acute Lymphoblastic Leukemia Patients Who Were Treated With or Without Imatinib	2013
Dr Lisa Russell Professor Christine Harrison FRCPath FMedSci	Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL	2013
Dr Amir Enshaei Claire Schwab Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Long-term follow-up of ETV6-RUNX1 ALL reveals that NCI risk, rather than secondary genetic abnormalities, is the key risk factor	2013
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Loss of chromosomes is the primary event in near-haploid and low-hypodiploid acute lymphoblastic leukemia	2013
Professor Christine Harrison FRCPath FMedSci	Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Munster AML-study group	2013
Professor Christine Harrison FRCPath FMedSci	Pediatric Acute Myeloid Leukemia with T(8;16)(P11;P13); A Distinct Clinical and Biological Entity. Results of a Collaborative Study by the International Berlin-Frankfurt-Munster AML Study Group ENTITY. RESULTS OF A COLLABORATIVE STUDY BY THE INTERNATIONAL BERLIN- FRANKFURT-MUNSTER AML STUDY GROUP	2013
Professor Anthony Moorman Claire Schwab Professor Christine Harrison FRCPath FMedSci	Risk-Directed Treatment Intensification Significantly Reduces the Risk of Relapse Among Children and Adolescents With Acute Lymphoblastic Leukemia and Intrachromosomal Amplification of Chromosome 21: A Comparison of the MRC ALL97/99 and UKALL2003 Trials	2013
Professor Christine Harrison FRCPath FMedSci	Targeting signaling pathways in acute lymphoblastic leukemia: new insights	2013
Dr Emma Fairhall Dr Michelle Charles Karen Wallace Claire Schwab Professor Christine Harrison FRCPath FMedSci et al.	The B-13 hepatocyte progenitor cell resists pluripotency induction and differentiation to non-hepatocyte cells.	2013
Professor Anthony Moorman Dr Lucy Chilton Dr Amir Enshaei Professor Christine Harrison FRCPath FMedSci	The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated on UKALLXII/ECOG2993	2013
Professor Anthony Moorman Dr Lucy Chilton Dr Amir Enshaei Professor Christine Harrison FRCPath FMedSci	The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated in the UKALLXII/ECOG2993 trial	2013
Dr Emma Fairhall Claire Schwab Professor Christine Harrison FRCPath FMedSci Dr Karen Wallace Professor Matthew Wright et al.	The Hepatic Progenitor B-13 Cell Line Engrafts into the Mouse Liver and Transdifferentiates in Vivo	2013
Professor Anthony Moorman Claire Schwab Hannah Ensor Dr Lisa Russell Heather Morrison et al.	IGH@ Translocations, CRLF2 Deregulation and Microdeletions in Adolescents and Adults with Acute Lymphoblastic Leukemia	2012
Professor Graham Jackson Professor Christine Harrison FRCPath FMedSci Professor Simon Bailey	Burkitt's lymphoma	2012
Professor Christine Harrison FRCPath FMedSci	Clinical Impact of Additional Cytogenetic Aberrations and Treatment in Pediatric t(8;21)-Positive AML: Results from an International Retrospective I-BFM-SG Study	2012
Claire Schwab Dr Lucy Chilton Dr Amir Enshaei Heather Morrison Lisa Jones et al.	Clinical Relevance of Genes Commonly Deleted in Childhood B-Cell Precursor ALL (BCP-ALL)	2012
Professor Anthony Moorman Dr Amir Enshaei Dr Lucy Chilton Claire Schwab Professor Christine Harrison FRCPath FMedSci et al.	Delineation of Risk Factors in Paediatric Acute Lymphoblastic Leukaemia with Favourable Cytogenetics	2012
Claire Schwab Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Episomal amplification of NUP214-ABL1 fusion gene in B-cell acute lymphoblastic leukemia	2012
Claire Schwab Dr Lucy Chilton Heather Morrison Lisa Jones Dr Halima Al-shehhi et al.	Genes Commonly Deleted in Childhood B-Cell Precursor ALL (BCP-ALL) Are Associated with Major Cytogenetic Subgroups	2012
Professor Christine Harrison FRCPath FMedSci	Genomic Analysis Drives Tailored Therapy in Poor Risk Childhood Leukemia	2012
Dr Lisa Russell Lisa Jones Dr Amy Erhorn Dr Amir Enshaei Dino Mašić et al.	Immunoglobulin Heavy Chain Locus (IGH@) Translocations in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Incidence and Risk Stratification	2012
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman Claire Schwab	Intrachromosomal Amplification of Chromosome 21(iAMP21): Cytogenetic Characterisation and Outcome in Childhood B-Cell Precursor Acute Lymphoblastic Leukaemia (BCP-ALL). A Study On Behalf of the Ponte Di Legno International Childhood ALL Workshop	2012
Dr Lisa Russell Professor Christine Harrison FRCPath FMedSci	Leukemia Cells with a BCR-ABL1-Like signature and/or IKZF1 deletions, but Not High CRLF2 Expression, Are Predictive of an Unfavorable Prognosis in Childhood B Cell Precursor Acute Lymphoblastic Leukemia	2012
Hannah Ensor Professor Christine Harrison FRCPath FMedSci	Molecular versus flow cytometric MRD analysis - is there an explanation for discrepancies?	2012
Dr Lisa Russell Claire Schwab Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations	2012
Hannah Ensor Claire Schwab Dr Lisa Russell Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman et al.	Treatment outcome of CRLF2-rearranged childhood acute lymphoblastic leukaemia: a comparative analysis of the AIEOP-BFM and UK NCRI-CCLG study groups	2012
Professor Christine Harrison FRCPath FMedSci	Acute Lymphoblastic Leukemia	2011
Dr Paul Sinclair Dr Vikki Rand Hannah Ensor Professor Christine Harrison FRCPath FMedSci	Analysis of a breakpoint cluster reveals insight into the mechanism of intrachromosomal amplification in a lymphoid malignancy	2011
Hannah Ensor Claire Schwab Dr Lisa Russell Heather Morrison Dr Dino Masic et al.	Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial	2011
Dr Vikki Rand Dr Lisa Russell Claire Schwab Hannah Ensor Professor Julie Irving et al.	Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia	2011
Professor Christine Harrison FRCPath FMedSci	How do we decipher the genetic profile of acute lymphoblastic leukaemia?	2011
Professor Christine Harrison FRCPath FMedSci	Key pathways as therapeutic targets	2011
Professor Christine Harrison FRCPath FMedSci	Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study	2011
Professor Christine Harrison FRCPath FMedSci	Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11Q23/MLL-rearranged AML patients: Results of an international study	2011
Dr Lindsay Nicholson Charlotte Evans Elizabeth Matheson Lynne Minto Christopher Keilty et al.	Quantitative Proteomic Analysis Reveals Maturation As a Mechanism Underlying Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia and PAX5 As a Re-Sensitising Therapeutic Target	2011
Dr Sarra Ryan Dr Vikki Rand Claire Schwab Heather Morrison Elizabeth Matheson et al.	Ras Signalling Pathway and Novel Target Genes Related to Down Syndrome Contribute to the Development of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) in iAMP21 Patients	2011
Professor Christine Harrison FRCPath FMedSci	Results of a randomized trial in children with Acute Myeloid Leukaemia: Medical Research Council AML12 trial	2011
Dr Lisa Russell Professor Christine Harrison FRCPath FMedSci	A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia	2010
Professor Christine Harrison FRCPath FMedSci	Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia	2010
Dr Lisa Russell Professor Christine Harrison FRCPath FMedSci	Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia	2010
Professor Christine Harrison FRCPath FMedSci	Clinical Impact of Additional Cytogenetic Aberrations and Complex Karyotype In Pediatric 11q23/MLL Rearranged AML Results from an International Retrospective Study	2010
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Cytogenetics of Childhood Acute Myeloid Leukemia: United Kingdom Medical Research Council Treatment Trials AML 10 and 12	2010
Dr Nicholas Bown Professor Christine Harrison FRCPath FMedSci	Cytogenetics of long-term survivors of ETV6-RUNX1 fusion positive acute lymphoblastic leukemia	2010
Professor Christine Harrison FRCPath FMedSci	Detection of prognostically relevant genetic abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfurt-Munster study group	2010
Dr Lisa Russell Professor Christine Harrison FRCPath FMedSci	Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group	2010
Claire Schwab Lisa Jones Heather Morrison Dr Sarra Ryan Professor Christine Harrison FRCPath FMedSci et al.	Evaluation of Multiplex Ligation-Dependent Probe Amplification as a Method for the Detection of Copy Number Abnormalities in B-Cell Precursor Acute Lymphoblastic Leukemia	2010
Professor Christine Harrison FRCPath FMedSci	Genetic aberrations in paediatric acute leukaemias and implications for management of patients	2010
Professor Christine Harrison FRCPath FMedSci	Haploinsufficiency of the MLL and TOB2 genes in lymphoid malignancy	2010
Professor Christine Harrison FRCPath FMedSci	Long-term follow-up of the United Kingdom medical research council protocols for childhood acute lymphoblastic leukaemia, 1980-2001	2010
Professor Christine Harrison FRCPath FMedSci Claire Schwab	PHF6 mutations in T-cell acute lymphoblastic leukemia	2010
Professor Anthony Moorman Hannah Ensor Dr Lucy Chilton Claire Schwab Professor Christine Harrison FRCPath FMedSci et al.	Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial	2010
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Refinement of cytogenetic classification in acute myeloid leukaemia: Determination of prognostic significance of rarer recurring chromosomal abnormalities amongst 5,876 younger adult patients treated in the UK Medical Research Council trials	2010
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials	2010
Professor Christine Harrison FRCPath FMedSci	The t(14;20) is a poor prognostic factor in myeloma but is associated with long-term stable disease in monoclonal gammopathies of undetermined significance	2010
Professor Julie Irving Professor James Allan Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk	2010
Sarina Sulong Professor Anthony Moorman Professor Julie Irving Marian Case Professor Simon Bailey et al.	A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups	2009
Dr Lisa Russell Professor Olaf Heidenreich Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	A novel translocation, t(14;19)(q32;p13) involving IGHalpha and the cytokine receptor for erythropoietin	2009
Professor Christine Harrison FRCPath FMedSci	Acute Lymphoblastic Leukaemia	2009
Professor Christine Harrison FRCPath FMedSci	Acute Myeloid Leukaemia	2009
Professor Christine Harrison FRCPath FMedSci	Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia	2009
Dr Lisa Russell Professor Olaf Heidenreich Professor Julie Irving Professor Anthony Moorman Heather Morrison et al.	Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia	2009
Professor Christine Harrison FRCPath FMedSci	Down's Syndrome Acute Lymphoblastic Leukemia: A Highly Heterogeneous Disease Driven by an Aberrant CRLF2/JAK2 Cooperation - A Report from the Ibfm-Study GROUP	2009
Professor Christine Harrison FRCPath FMedSci	FISH (Fluoresecence in situ Hybridization) as a Tool for the Detection of Significant Chromosomal Abnormalities in Childhood Leukaemia	2009
Professor Christine Harrison FRCPath FMedSci	Frequent upregulation of MYC in plasma cell leukemia.	2009
Professor Christine Harrison FRCPath FMedSci	Gain of 1q21 Does Not Predict for Immediate Progression in MGUS	2009
Professor Anthony Moorman Dr Michael Griffiths Dr Tina Davies Professor Christine Harrison FRCPath FMedSci	Heterogeneous breakpoints in patients with acute lymphoblastic leukemia and the dic(9;20)(p11-13;q11) show recurrent involvement of genes at 20q11.21	2009
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Heterogeneous patterns of amplification of the NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia	2009
Professor Christine Harrison FRCPath FMedSci	Identification of Novel Prognostic Subgroups in Childhood 11Q23/MLL-Rearranged Acute Myeloid Leukemia	2009
Professor Christine Harrison FRCPath FMedSci	ISCN (2009): Important revisions and new additions to molecular methods for copy number detection for cytogenetic analysis	2009
Professor Christine Harrison FRCPath FMedSci	Loss of 1p and rearrangement of MYC are associated with progression of smouldering myeloma to myeloma: sequential analysis of a single case	2009
Professor Anthony Moorman Dr Michael Griffiths Professor Julie Irving Professor Christine Harrison FRCPath FMedSci	Methylation of tumour suppressor gene promoters in the presence and absence of transcriptional silencing in high hyperdiploid acute lymphoblastic leukaemia	2009
Professor Christine Harrison FRCPath FMedSci	Modeling the molecular consequences of unbalanced translocations in cancer: lessons from acute lymphoblastic leukemia	2009
Professor Christine Harrison FRCPath FMedSci	Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study	2009
Professor Christine Harrison FRCPath FMedSci	Novel prognostics subgroups in childhood 11Q23/MLL-rearranged acute myeloid leukemia as defined by translocation partners: A retrospective international study	2009
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Prognostic Relevance of Cytogenetics in Childhood Acute Lymphoblastic Leukaemia (ALL): Final Results From MRC ALL97	2009
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Refinement of cytogenetic classification in AML: Determination of prognostic significance of rare recurring chromosomal abnormalities amongst 5635 younger adults treated in the UK MRC Trails	2009
Professor Christine Harrison FRCPath FMedSci	Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia	2009
Professor Christine Harrison FRCPath FMedSci	Strong association of the HLA-DP6 supertype with childhood leukaemia is due to a single allele, DPB1*0601	2009
Professor Christine Harrison FRCPath FMedSci	Timing of acquisition of deletion 13 in plasma cell dyscrasias is dependent on genetic context	2009
Professor Christine Harrison FRCPath FMedSci	Topics in cytogenetics of acute leukaemias	2009
Dr Vikki Rand Dr Lisa Russell Professor Julie Irving Lisa Jones Dr Dino Masic et al.	What Is the Initiating Mechanism of iAMP21 in Childhood B Cell Precursor ALL?	2009
Professor Christine Harrison FRCPath FMedSci	HLA-DPB1 supertype-associated protection from childhood leukaemia: relationship to leukaemia karyotype and implications for prevention	2008
Professor Christine Harrison FRCPath FMedSci	Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: an iBFM-SG study	2008
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Cytogenetic-specific heterogeneity in the kinetics of minimal residual disease (MIRD) clearance in childhood lymphoblastic leukaemia (ALL)	2008
Professor Christine Harrison FRCPath FMedSci	Disruption of ETV6 in intron 2 results in upregulatory and insertional events in childhood acute lymphoblastic leukaemia	2008
Elizabeth Matheson Lynne Minto Professor Anthony Moorman Dr Andrew Hall Professor Julie Irving et al.	Heterogeneous breakpoints target PAX5 in acute lymphoblastic leukaemia patients with dicentric chromosomes	2008
Dr Lisa Russell Professor Christine Harrison FRCPath FMedSci	IDENTIFICATION OF MULTIPLE NOVEL IGH@ TRANSLOCATIONS IN ADOLESCENT ACUTE LYMPHOBLASTIC LEUKAEMIA.	2008
Dr Lisa Russell Professor Anthony Moorman Professor Olaf Heidenreich Professor Christine Harrison FRCPath FMedSci	IGH@ Translocations Involving the Pseudoautosomal Region 1 (PAR1) of Both Sex Chromosomes Deregulate the Cytokine Receptor-Like Factor 2 (CRLF2) Gene in B Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)	2008
Professor Anthony Moorman Sarina Sulong Professor Julie Irving Marian Case Lynne Minto et al.	Inactivation of CDKN2A in childhood acute lymphoblastic leukaemia (ALL) occurs principally by deletion and is strongly correlated with cytogenetic subgroups	2008
Marian Case Elizabeth Matheson Lynne Minto Professor Christine Harrison FRCPath FMedSci Dr Nicholas Bown et al.	Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting	2008
Dr Lisa Russell Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	t(6;14)(p22;q32): a new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL)	2008
Marian Case Dr Tina Davies Professor Anthony Moorman Dr Andrew Hall Professor Julie Irving et al.	The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR1	2008
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	The Spectrum and Prognostic Relevance of Additional Abnormalities, Involving 12p and 21q, in Children with ETV6-RUNX1 Positive Acute Lymphoblastic Leukaemia (ALL)	2008
Elizabeth Matheson Professor Anthony Moorman Dr Andrew Hall Professor Christine Harrison FRCPath FMedSci Professor Julie Irving et al.	Variable breakpoints target PAX5 in patients with dicentric chromosomes: A model for the basis of unbalanced translocations in cancer	2008
Professor Christine Harrison FRCPath FMedSci	A de novo (1;2;3;15;18) chromosome rearrangement with six non reciprocal translocations.	2007
Professor Christine Harrison FRCPath FMedSci Dr Fiona Moorman	A multicenter evaluation of comprehensive analysis of MLL translocations and fusion gene partners in acute leukemia using the MLL FusionChip device	2007
Professor Christine Harrison FRCPath FMedSci	Advances in molecular cytogenetics to study the leukaemia genome.	2007
Dr Lisa Russell Professor Christine Harrison FRCPath FMedSci	Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL)	2007
Dr Frederik van Delft Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization	2007
Professor Anthony Moorman Marian Case Professor Julie Irving Dr Andrew Hall Professor Christine Harrison FRCPath FMedSci et al.	Genomic profiling reveals multiple genetic targets in ETV6-RUNX1 positive acute lymphoblastic leukaemia (ALL)	2007
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Intrachromosomal amplification of chromosome 21 (iAMP21) arises from a breakage-fusion-bridge cycle	2007
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Karyotype is an independent prognostic factor in adult acute lymphoblastic leukaemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 Trial	2007
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Molecular cytogenetic characterisation of TCF3 (E2A)/19p13 rearrangements in acute lymphoblastic leukaemia	2007
Professor Christine Harrison FRCPath FMedSci	Monosomy 7 and deletion 7q in children and adolescents with acute myeloid leukemia: An international retrospective study	2007
Professor Christine Harrison FRCPath FMedSci	Outcome of treatment in children with hypodiploid acute lymphoblastic leukemia	2007
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21)	2007
Adillah Binti Yusof Professor Julie Irving Marian Case Lynne Minto Professor Christine Harrison FRCPath FMedSci et al.	Red blood cell alloimmunization is affected by depletion of donor white cell subsets	2007
Elizabeth Matheson Lynne Minto Professor Anthony Moorman Dr Andrew Hall Professor Julie Irving et al.	Variable Breakpoints Target PAX5 in Patients with Dicentric Chromosomes: A Model for the Basis of Unbalanced Translocations in Cancer	2007
Professor Christine Harrison FRCPath FMedSci	A diminutive chromosome 21 centromere in acute lymphoblastic leukemia	2006
Dr Andrew Hall Sarina Sulong Professor Christine Harrison FRCPath FMedSci Lynne Minto Dr Nicholas Bown et al.	Assessment of aneuploidy in childhood acute lymphoblastic leukaemia using high density oligonucleotide arrays.	2006
Dr Frederik van Delft Professor Christine Harrison FRCPath FMedSci	Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21	2006
Sarina Sulong Professor Julie Irving Marian Case Lynne Minto Dr Nicholas Bown et al.	Comprehensive analysis of p16(INK4a) in childhood acute lymphoblastic leukemia reveals homozygous deletion, haploinsufficiency and acquired isodisomy at the 9p locus with intact p16(INK4a).	2006
Professor Christine Harrison FRCPath FMedSci	Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma	2006
Professor Julie Irving Lynne Minto Elizabeth Matheson Marian Case Professor Simon Bailey et al.	Mutation in genes impacting on the RAS-RAF-MEK-ERK pathway are found at high incidence in childhood acute lymphoblastic leukemia at both diagnosis and at relapse.	2006
Dr Lisa Russell Professor Christine Harrison FRCPath FMedSci	Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia	2006
Professor Anthony Moorman Dr Nicholas Bown Professor Christine Harrison FRCPath FMedSci	PAX5-ETV6 fusion in acute lymphoblastic leukaemia des not define the dic(9;12)	2006
Professor Christine Harrison FRCPath FMedSci	The Eighth International Childhood Acute Lymphoblastic Leukemia Workshop ('Ponte di legno meeting') report: Vienna, Austria, April 27-28, 2005	2006
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	ETV6/RUNX1 fusion at diagnosis and relapse: some prognostic indications	2005
Professor Christine Harrison FRCPath FMedSci	Age has a profound effect on the incidence and significance of chromosome abnormalities in myeloma	2005
Dr Paul Sinclair Professor Christine Harrison FRCPath FMedSci	Analysis of balanced rearrangements of chromosome 6 in acute leukemia: clustered breakpoints in q22-q23 and possible involvement of c-MYB in a new recurrent translocation, t(6;7)(q23;q32 through 36)	2005
Professor Christine Harrison FRCPath FMedSci	Cytogenetics of leukaemia and lymphoma	2005
Professor Christine Harrison FRCPath FMedSci	Del (9q) AML: clinical and cytological characteristics and prognostic implications	2005
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Derivative chromosome 9 deletions are a significant feature of childhood Philadelphia chromosome positive acute lymphoblastic leukaemia	2005
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Interphase molecular cytogenetic screening for chromosomal abnormalities of prognostic significance in childhood acute lymphoblastic leukaemia: a UK Cancer Cytogenetics Group Study	2005
Professor Christine Harrison FRCPath FMedSci	Karyotyping lymph node biopsies in non-Hodgkin's lymphoma	2005
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	No prognostic effect of additional chromosomal abnormalities in children with acute lymphoblastic leukemia and 11q23 abnormalities	2005
Professor Christine Harrison FRCPath FMedSci	Treatment strategy and long-term results in paediatric patients treated in consecutive UK AML trials	2005
Dr Paul Sinclair Professor Christine Harrison FRCPath FMedSci	A fluorescence in situ hybridization map of 6q deletions in acute lymphocytic leukemia: identification and analysis of a candidate tumor suppressor gene	2004
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Amplification of the ABL gene in T-cell acute lymphoblastic leukemia	2004
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Comparative expressed sequence hybridization studies of high-hyperdiploid childhood acute lymphoblastic leukemia	2004
Professor Christine Harrison FRCPath FMedSci	Complex chromosomal abnormalities in utero, 5 years before leukaemia	2004
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Is trisomy 5 a distinct cytogenetic subgroup in acute lymphoblastic leukemia?	2004
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	MLL translocations with concurrent 3' deletions: interpretation of FISH results	2004
Professor Christine Harrison FRCPath FMedSci	Molecular cytogenetics in childhood leukaemia	2004
Professor Christine Harrison FRCPath FMedSci	MRC trials in childhood acute myeloid leukaemia	2004
Professor Christine Harrison FRCPath FMedSci	Secondary cytogenetic aberrations in childhood Philadelphia chromosome positive acute lymphoblastic leukemia are nonrandom and may be associated with outcome	2004
Professor Christine Harrison FRCPath FMedSci	Successful treatment without cranial radiotherapy of children receiving intensified chemotherapy for acute lymphoblastic leukaemia: results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI (ISRC TN 16757172)	2004
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	t(14;19)(q32;q13): a recurrent translocation in B-cell precursor acute lymphoblastic leukemia	2004
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Three distinct subgroups of hypodiploidy in acute lymphoblastic leukaemia	2004
Professor Christine Harrison FRCPath FMedSci	A unique variant of ETV6/AML1 fusion in a child with acute lymphoblastic leukemia	2003
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome	2003
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: a study of 20 cases	2003
Professor Christine Harrison FRCPath FMedSci	Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements	2003
Professor Christine Harrison FRCPath FMedSci	Cytogenetics of multiple myeloma: interpretation of fluorescence in situ hybridization results	2003
Professor Christine Harrison FRCPath FMedSci	Cytogenetics of multiple myeloma: interpretation of fluorescence in situ hybridization results	2003
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Frequency of ETV6/AML1 fusion in adult acute lymphoblastic leukaemia - response to Cuneo et al.	2003
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Outcome heterogeneity in childhood high-hyperdiploid acute lymphoblastic leukemia	2003
Professor Christine Harrison FRCPath FMedSci Dr Michael Griffiths	Prenatal origin of hyperdiploid acute lymphoblastic leukemia in identical twins	2003
Professor Christine Harrison FRCPath FMedSci	ETV6/AML1 fusion by FISH in adult acute lymphoblastic leukaemia.	2002
Professor Christine Harrison FRCPath FMedSci	Clinical features, cytogenetics and outcome in acute lymphoblastic and myeloid leukaemia of infancy: report from the MRC Childhood Leukaemia working party	2002
Professor Christine Harrison FRCPath FMedSci	Cytogenetics and molecular genetics of acute lymphoblastic leukemia	2002
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Involvement of the MLL gene in T-lineage acute lymphoblastic leukaemia	2002
Professor Christine Harrison FRCPath FMedSci	Translocations of 14q32 and deletions of 13q14 are common chromosomal abnormalities in systemic amyloidosis (AL)	2002
Professor Christine Harrison FRCPath FMedSci	Treatment of infants with lymphoblastic leukaemia	2002
Professor Christine Harrison FRCPath FMedSci	Treatment of infants with lymphoblastic leukaemia: results of the UK Infant Protocols 1987-1999	2002
Professor Christine Harrison FRCPath FMedSci	Acute Lymphoblastic Leukaemia	2001
Professor Christine Harrison FRCPath FMedSci Dr Tim Butler	Cross species color banding in ten cases of myeloid malignancies with complex karyotypes	2001
Professor Christine Harrison FRCPath FMedSci	Determinants of outcome after intensified therapy of childhood lymphoblastic leukaemia: results from Medical Research Council United Kingdom acute lymphoblastic leukaemia XI protocol	2001
Professor Christine Harrison FRCPath FMedSci	Heterogeneity of VH-JH gene rearrangement patterns: an insight into the biology of B cell precursor ALL	2001
Professor Christine Harrison FRCPath FMedSci	Molecular tracking of leukemogenesis in a triplet pregnancy	2001
Professor Christine Harrison FRCPath FMedSci	The detection and significance of chromosomal abnormalities in childhood acute lymphoblastic leukaemia	2001
Professor Christine Harrison FRCPath FMedSci	The Leukaemia Research Fund/United Kingdom Cancer Cytogenetics Group Karyotype Database in acute lymphoblastic leukaemia: a valuable resource for patient management	2001
Professor Christine Harrison FRCPath FMedSci	The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial	2001
Professor Christine Harrison FRCPath FMedSci	Three further cases of t(8;14)(q11.2;q32) in acute lymphoblastic leukemia	2001
Gavin Cuthbert Professor Christine Harrison FRCPath FMedSci Dr Michael Griffiths Dr Nicholas Bown	MLL amplification in acute leukaemia: a United Kingdom Cancer Cytogenetics Group (UKCCG) study	2000
Professor Christine Harrison FRCPath FMedSci	Analysis of ETV6/AML1 abnormalities in acute lymphoblastic leukaemia: incidence, alternative spliced forms and minimal residual disease value	2000
Dr Paul Sinclair Professor Christine Harrison FRCPath FMedSci	Deletion of 6q16-q21 in human lymphoid maligancies: a mapping and deletion analysis	2000
Professor Anthony Moorman Professor Christine Harrison FRCPath FMedSci	Monosomy 20 as a pointer to dicentric (9;20) in acute lymphoblastic leukaemia	2000
Professor Christine Harrison FRCPath FMedSci	Multiplex fluorescence in situ hybridization and cross species color banding of a case of chronic myeloid leukemia in blastic crisis with a complex Philadelphia translocation	2000
Andrew Walker Professor Christine Harrison FRCPath FMedSci	Sequential FISH reveals an abnormal karyotype involving 14 chromosomes in a child with acute lymphoblastic leukemia	2000
Professor Christine Harrison FRCPath FMedSci	t(7;12)(q36;p13), a new recurrent translocation involving ETV6 in infant leukemia	2000
Professor Christine Harrison FRCPath FMedSci	The genetics of childhood acute lymphoblastic leukaemia	2000
Professor Christine Harrison FRCPath FMedSci	The lymphomas and chronic lymphoproliferative disorders	2000
Professor Christine Harrison FRCPath FMedSci	The management of patients with leukaemia: the role of cytogenetics in this molecular era	2000
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman Emeritus Professor Alan Craft Dr Juliet Hale Dr Jennifer Kernahan et al.	The United Kingdom Childhood Cancer Study: objectives, materials and methods	2000
Professor Christine Harrison FRCPath FMedSci	A simple, robust, validated and highly predictive index for the determination of risk-directed therapy in acute myeloid leukaemia derived from the MRC AML 10 trial	1999
Professor Christine Harrison FRCPath FMedSci	A simple, robust, validated and highly predictive index for the determination of risk-directed therapy in acute myeloid leukaemia derived from the MRC AML 10 trial. United Kingdom Medical Research Council's Adult and Childhood Leukaemia Working Parties	1999
Professor Christine Harrison FRCPath FMedSci	Abnormal cytogenetic clones in patients with aplastic anaemia: response to immunosuppressive therapy	1999
Professor Christine Harrison FRCPath FMedSci	Fluorescence in situ hybridization analysis of masked (8;21)(q22;q22) translocations	1999
Professor Christine Harrison FRCPath FMedSci	Fluorescence In Situ Hybridization Analysis of Masked (8;21)(q22;q22) Translocations	1999
Professor Christine Harrison FRCPath FMedSci	Investigation of clonal involvement of myeloid cells in Philadelphia-positive and high hyperdiploid acute lymphoblastic leukemia	1999
Professor Christine Harrison FRCPath FMedSci	Investigation of minimal residual disease in childhood and adult acute lymphoblastic leukaemia by molecular analysis	1999
Professor Christine Harrison FRCPath FMedSci	Abnormalities of the ETV6 gene occur in the majority of patients with aberrations of the short arm of chromosome 12: a combined PCR and Southern blotting analysis	1998
Professor Christine Harrison FRCPath FMedSci Professor Anthony Moorman	Ten novel 11q23 chromosomal partner sites	1998
Professor Christine Harrison FRCPath FMedSci	The importance of cytogenetics and associated molecular techniques in the management of patients with leukaemia	1998
Professor Christine Harrison FRCPath FMedSci	The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial	1998
Professor Christine Harrison FRCPath FMedSci	A chromosome 14q11/TCR alpha/delta specific yeast artificial chromosome improves the detection rate and characterization of chromosome abnormalities in T-lymphoproliferative disorders	1997
Professor Christine Harrison FRCPath FMedSci	Analysis of chromosome 6 deletions in lymphoid malignancies provides evidence for a region of minimal deletion within a 2-megabase segment of 6q21	1997
Professor Christine Harrison FRCPath FMedSci	Autografting in Philadelphia (Ph)+ chronic myeloid leukaemia using cultured marrow: an update of a pilot study	1997
Professor Christine Harrison FRCPath FMedSci	Evaluation of cytogenetic conversion to Ph^- haemopoiesis in long-term bone marrow culture for patients with chronic myeloid leukaemia on conventional hydroxyurea therapy, on pulse high-dose hydroxyurea and on interferon-alpha	1996
Professor Christine Harrison FRCPath FMedSci	An interstitial deletion in the rearranged T-cell receptor gamma chain locus in a case of T-cell acute lymphoblastic leukaemia	1995
Professor Christine Harrison FRCPath FMedSci	Detection of CBFB/MYH11 transcripts in patients with inversion and other abnormalities of chromosome 16 at presentation and remission	1995
Professor Christine Harrison FRCPath FMedSci	Dicentric (9;12) in acute lymphocytic leukemia and other hematological malignancies: report from a dic(9;12) study group	1995
Professor Christine Harrison FRCPath FMedSci	Retinoblastoma in association with the chromosome breakage syndromes Fanconi's anaemia and Bloom's syndrome: clinical and cytogenetic findings	1995
Professor Christine Harrison FRCPath FMedSci	Acute lymphoblastic leukemia following Hodgkins Disease is associated with a poor prognosis	1994
Dr Mauro Santibanez Koref Professor Christine Harrison FRCPath FMedSci	Deletion of a common region on the long arm of chromosome 6 in acute lymphoblastic leukaemia	1994
Professor Christine Harrison FRCPath FMedSci	The karyotype of Alligator mississippiensis, and chromosomal mapping of the ZFY/X homologue, Zfc	1994
Professor Christine Harrison FRCPath FMedSci	Localization of the estrogen receptor locus (ESR) to chromosome 6q25.1 by FISH and a simple post-FISH banding technique	1993
Professor Christine Harrison FRCPath FMedSci	Reply to letter to the editors: t(12;17)(p12-13;q11-q12) associated with biphenotypic leukaemia	1993
Professor Christine Harrison FRCPath FMedSci	Residual Ph^- cells in chronic myeloid leukemia: detection and usefulness	1993
Professor Christine Harrison FRCPath FMedSci	Structural abnormalities of the X chromosome in non-Hodgkin's lymphoma	1993
Professor Christine Harrison FRCPath FMedSci	Three cases of the myelodysplastic syndrome with pericentric inversion of chromosome 16	1993
Professor Christine Harrison FRCPath FMedSci	Prognostic significance of the balanced t(1;19) and unbalanced der(19)t(1;19) translocations in acute lymphoblastic leukemia	1992
Professor Christine Harrison FRCPath FMedSci	The lymphomas and chronic lymphoproliferative disorders	1992
Professor Christine Harrison FRCPath FMedSci	Alveolar rhabdomyosarcoma with del(13q14)	1991
Professor Christine Harrison FRCPath FMedSci	Hyperfibrotic myelodysplasia	1991
Professor Christine Harrison FRCPath FMedSci	Monocytoid B cell lymphoma	1991
Professor Christine Harrison FRCPath FMedSci	Myelodysplasia presenting as autoimmune haemolytic anaemia	1991
Professor Christine Harrison FRCPath FMedSci	Near haploid acute lymphoblastic leukemia: seven new cases and a review of the literature	1991
Professor Christine Harrison FRCPath FMedSci	Functional studies of bone marrow haemopoietic and stromal cells in the myelodysplastic syndrome (MDS)	1990
Professor Christine Harrison FRCPath FMedSci	T cell non-Hodgkin's lymphoma with uveitis, pancreatitis, digital gangrene and multiple chromosomal abnormalities	1990
Professor Christine Harrison FRCPath FMedSci	The use of cultured bone marrow cells in autologous transplantation	1990
Professor Christine Harrison FRCPath FMedSci	Acute monocytic leukaemia and t(2;6) (p21;q26) translocation	1989
Professor Christine Harrison FRCPath FMedSci	Fine-structural aspects of bromodeoxyuridine incorporation in sister chromatid differentiation and replication banding	1989
Professor Christine Harrison FRCPath FMedSci	The role of clinical cytogenetics in medicine: with special emphasis on oncology	1988
Professor Christine Harrison FRCPath FMedSci	A cell line from Wilms' tumour with deletion in short arm of chromosome II	1987
Professor Christine Harrison FRCPath FMedSci	A scanning electron microscopy study of double minutes from a human tumour cell line	1987
Professor Christine Harrison FRCPath FMedSci	Expression of human CD antigens, including CD1 and CD25, by human x mouse interlineage leukaemia hybrids	1987
Professor Christine Harrison FRCPath FMedSci	The growth of myelodysplastic bone marrow in long-term cultures	1987
Professor Christine Harrison FRCPath FMedSci	A structural basis for R- and T-banding: a scanning electron microscopy study	1986
Professor Christine Harrison FRCPath FMedSci	Marrow-Cells from a Significant Proportion of Patients with Acute Myelogenous Leukemia Can Establish Normal Hematopoiesis When Grown in Long-Term Bone-Marrow Culture (LTBMC)	1986
Professor Christine Harrison FRCPath FMedSci	Philadelphia-positive metaphases in the marrow after bone marrow transplantation for chronic granulocytic leukemia	1986
Professor Christine Harrison FRCPath FMedSci	Reconstitution of haemopoietic system with autologous marrow taken during relapse of acute myeloblastic leukaemia and grown in long-term culture	1986
Professor Christine Harrison FRCPath FMedSci	Scanning electron microscopy of human metaphase chromosomes	1986
Professor Christine Harrison FRCPath FMedSci	Extramedullary transformation of chronic myeloid leukaemia with a unique chromosome pattern	1985
Professor Christine Harrison FRCPath FMedSci	Investigation of human chromosome polymorphisms by scanning electron microscopy	1985
Professor Christine Harrison FRCPath FMedSci	Light and scanning electron microscopy of the same human metaphase chromosomes	1985
Professor Christine Harrison FRCPath FMedSci	The lymphomas and chronic lymphoproliferative disorders	1985
Professor Christine Harrison FRCPath FMedSci	The structural basis for C-banding	1985
Professor Christine Harrison FRCPath FMedSci	Chromosomal evidence of a common stem cell in acute lymphoblastic leukemia and chronic granulocytic leukemia	1984
Professor Christine Harrison FRCPath FMedSci	Influence of 12-O-tetradecanoylphorbol-13-acetate (TPA) on the susceptibility of K562 to natural cytotoxicity: evidence for clonal variation in differentiation-induced changes of lytic sensitivity	1984
Professor Christine Harrison FRCPath FMedSci	Lumen formation in the developing mouse mammary gland	1983
Professor Christine Harrison FRCPath FMedSci	Scanning electron microscopy of variations in human metaphase chromosome structure revealed by Giemsa banding	1983
Professor Christine Harrison FRCPath FMedSci	The fragile X: a scanning electron microscope study	1983
Professor Christine Harrison FRCPath FMedSci	High-resolution scanning electron microscopy of human metaphase chromosomes	1982
Professor Christine Harrison FRCPath FMedSci	Scanning electron microscopy of the G-banded human karyotype	1981
Professor Christine Harrison FRCPath FMedSci	Cell migration through three-dimensional gels of native collagen fibres: collagenolytic activity is not required for the migration of two permanent cell lines	1980
Professor Christine Harrison FRCPath FMedSci	Changes in surface morphology associated with ageing and carcinogen treatment of Chinese hamster lung cells	1980
Professor Christine Harrison FRCPath FMedSci	Cell surface morphology after trypsinisation depends on initial cell shape	1979