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Non-cystic fibrosis bronchiectasis

Lookup NU author(s): Professor Christopher WardORCiD, Dr James Lordan, Dr Robert Rutherford

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Abstract

Bronchiectasis is a chronic debilitating condition with considerable phenotypic diversity. A vicious cycle of infection and inflammation exists in damaged airways with patients suffering from persistent cough, purulent sputum production, recurrent chest infections and general malaise. The associated burden of disease in terms of increased morbidity, reduced quality of life and the socioeconomic cost of long-term management is significant. Further research is essential to improve our understanding of the development and progression of this disease. This article reviews what is currently known about bronchiectasis, its pathophysiology, aetiology and management strategies.

Publication metadata

Author(s): McDonnell MJ, Ward C, Lordan JL, Rutherford RM

Publication type: Review

Publication status: Published

Journal: QJM: An International Journal of Medicine

Year: 2013

Volume: 106

Issue: 8

Pages: 709-715

Print publication date: 30/05/2013

ISSN (print): 1460-2725

ISSN (electronic): 1460-2393

Publisher: OXFORD UNIV PRESS

URL: http://dx.doi.org/10.1093/qjmed/hct109

DOI: 10.1093/qjmed/hct109

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