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Browsing publications by Professor Christopher Ward.

Newcastle AuthorsTitleYearFull text
Professor Christopher Ward
Air Pollution as a Risk Factor for Lung Cancer: Potential Mechanisms2022
Professor Christopher Ward
Antimicrobial therapies for prevention of recurrent acute exacerbations of COPD (AECOPD): beyond the guidelines2022
Dr Carlos Echevarria
Dr Simon Doe
Dr Malcolm Brodlie
Professor Christopher Ward
Dr Stephen Bourke
et al.
Elexacaftor-Tezacaftor-Ivacaftor improve Gastro-Oesophageal reflux and Sinonasal symptoms in advanced cystic fibrosis2022
Kyle Stanforth
Dr Peter Chater
Dr Iain Brownlee
Dr Matthew Wilcox
Professor Christopher Ward
et al.
In vitro modelling of the mucosa of the oesophagus and upper digestive tract: narrative review2022
Dr Iram Haq
Dr Mike Althaus
Dr Vinciane Saint-Criq
Dr Bernard Verdon
Dr Jen Townshend
et al.
Clinical and molecular characterisation of the R751L-CFTR mutation2021
Catherine Hatton
Dr Rachel Botting
Dr Maria Duenas Fadic
Dr Iram Haq
Dr Bernard Verdon
et al.
Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-22021
Dr Michael Mather
Dr Bernard Verdon
Dr Rachel Botting
Justin Engelbert
Livia Delpiano
et al.
Development of a physiological model of human middle ear epithelium2021
Dr Michael Mather
Steven Powell
Dr Ben Talks
Professor Christopher Ward
Professor Muzlifah Haniffa
et al.
Dysregulation of immune response in otitis media2021
Professor Christopher Ward
Eosinophilic Granulomatosis with Polyangiitis2021
Professor Christopher Ward
Fully integrating pathophysiological insights in COPD: an updated working disease model to broaden therapeutic vision2021
Abdullah Althuwaybi
Maher Al Quaimi
Amaran Krishnan
Rhys Jones
Professor Jeffrey Pearson
et al.
Hospitalization outcomes for COVID-19 in patients with interstitial lung disease: A potential role for aerodigestive pathophysiology?2021
Professor Christopher Ward
Mechanistic Insights on EMT and Smoking-Related COPD2021
Nina Jordan
Dr Sam Tingle
Victoria Shuttleworth
Katie Cooke
Dr Rachael Redgrave
et al.
MiR-126-3p Is Dynamically Regulated in Endothelial-to-Mesenchymal Transition during Fibrosis2021
Professor Christopher Ward
Amal Alamer
Bronchiectasis in the Elderly—a Disease That Has Not Gone Away2020
Professor Christopher Ward
Dr John Perry
Amaran Krishnan
Dr Rhys Jones
Professor Jeffrey Pearson
et al.
Clonally related viable nontuberculous mycobacteria in gastric juice and sputum in people with cystic fibrosis2020
Dr Emily Mavin
Dr Bernard Verdon
Sean Carrie
Dr Vinciane Saint-Criq
Jason Powell
et al.
Real-time measurement of cellular bioenergetics in fully differentiated human nasal epithelial 2 cells grown at air-liquid-interface2020
Dr Aaron Ions Gardner
Dr Iram Haq
Professor John Simpson
Dr Vinciane Saint-Criq
Dr Bernard Verdon
et al.
Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis2020
Professor Christopher Ward
Stability of eosinophilic inflammation in COPD bronchial biopsies2020
Jason Powell
Dr Bernard Verdon
Emerita Professor Janet Wilson
Professor John Simpson
Professor Jeffrey Pearson
et al.
Establishment of an immortalized human subglottic epithelial cell line2019
Professor Christopher Ward
Dr Gerard Meachery
Dr James Lordan
Professor Andrew Fisher
Emeritus Professor Nick Europe-Finner
et al.
Long-term effect of azithromycin in bronchiolitis obliterans syndrome2019
Dr Prosenjit Dutta
Dr Wendy Funston
Helen Mossop
Vicky Ryan
Rhys Jones
et al.
Randomised, double-blind, placebo-controlled pilot trial of omeprazole in idiopathic pulmonary fibrosis2019
Dr Vinciane Saint-Criq
Dr Iram Haq
Dr Aaron Ions Gardner
Professor Christopher Ward
Dr Malcolm Brodlie
et al.
Real-Time, Semi-Automated Fluorescent Measurement of the Airway Surface Liquid pH of Primary Human Airway Epithelial Cells2019
Professor Christopher Ward
Dr Zelal Kharaba
Regarding epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux2019
Professor Christopher Ward
The presence of Aspergillus fumigatus in asthmatic airways is not clearly related to clinical disease severity2019
Shameem Sultanali Ladak
Jason Powell
Professor Andrew Fisher
Professor Christopher Ward
Professor Simi Ali
et al.
The role of miR-200b-3p in modulating TGF-β1 induced injury in human bronchial epithelial cells2019
Professor Christopher Ward
Professor Jeffrey Pearson
Dr James Lordan
Professor Anthony De Soyza
A qualitative synthesis of gastro-oesophageal reflux in bronchiectasis: Current understanding and future risk2018
Professor Christopher Ward
Dr Robert Rutherford
Comorbidities and their impact2018
Professor Christopher Ward
Epithelial mesenchymal transition (EMT), a spectrum of states: role in lung development, homeostasis and disease2018
Jason Powell
Dr James Garnett
Dr Michael Mather
Dr Faye Cooles
Dr Bernard Verdon
et al.
Excess Mucin Impairs Subglottic Epithelial Host Defense in Mechanically Ventilated Patients2018
Professor Christopher Ward
Rhys Jones
Dr Melissa Friel
Pathophysiology in the Lung2018
Dr Desmond Murphy
Professor Christopher Ward
Professor Jeffrey Pearson
Response2018
Rhys Jones
Amaran Krishnan
Dr Malcolm Brodlie
Professor Jeffrey Pearson
Professor Stephen Bourke
et al.
Risk factors for lung disease progression in children with cystic fibrosis2018
Adil Aldhahrani
Jason Powell
Shameem Sultanali Ladak
Dr Mohammed Ali
Professor Simi Ali
et al.
The Potential Role of Bile Acids in Acquired Laryngotracheal Stenosis2018
Professor Christopher Ward
Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD)2017
Professor Christopher Ward
Airway inflammation and inhaled corticosteroids in COPD.2017
Zachary Shellman
Adil Aldhahrani
Dr Bernard Verdon
Dr Michael Mather
Professor Vinidh Paleri
et al.
Bile acids: a potential role in the pathogenesis of pharyngeal malignancy2017
Salam Ibrahim
Mark Turner
Dr Vinciane Saint-Criq
Dr James Garnett
Dr Iram Haq
et al.
CK2 is a key regulator of SLC4A2- mediated Cl-/HCO3- exchange in human airway epithelia2017
Adil Aldhahrani
Dr Bernard Verdon
Professor Christopher Ward
Professor Jeffrey Pearson
Effects of Bile acids on Human Airway Epithelial Cells; implications for aerodigestive diseases2017
Professor Christopher Ward
Epithelial mesenchymal transition (EMT) and non-small cell lung cancer (NSCLC): a mutual association with airway disease2017
Professor Christopher Ward
Epithelial-mesenchymal transition: A necessary new therapeutic target in chronic obstructive pulmonary disease?2017
Dr Hafez Al-momani
Rhys Jones
Professor Stephen Bourke
Dr Simon Doe
Dr John Perry
et al.
Nontuberculous mycobacteria in gastrostomy fed patients with cystic fibrosis2017
Professor Christopher Ward
Profiling cellular and inflammatory changes in the airway wall of mild to moderate COPD2017
Professor Christopher Ward
Professor Jeffrey Pearson
The potential role of aspiration in the asthmatic airway2017
Professor Christopher Ward
Transforming growth factor (TGF) ß1 and Smad signaling pathways: A likely key to EMT-associated COPD pathogenesis2017
Dr Aaron Ions Gardner
Professor Christopher Ward
Dr Malcolm Brodlie
β1-integrin accumulates in cystic fibrosis luminal airway epithelial membranes and decreases sphingosine promoting bacterial infections2017
Professor Christopher Ward
β-catenin, Twist and Snail: Transcriptional regulation of EMT in smokers and COPD, and relation to airflow obstruction2017
Professor Christopher Ward
A Study To Define The Microbiome Of The Asthmatic Airway2016
Dr Iram Haq
Dr Michael Gray
Dr James Garnett
Professor Christopher Ward
Dr Malcolm Brodlie
et al.
Airway surface liquid homeostasis in cystic fibrosis: pathophysiology and therapeutic targets2016
Professor Anthony De Soyza
Professor Christopher Ward
Comorbidities and the risk of mortality in patients with bronchiectasis: an international multicentre cohort study2016
Rhys Jones
Professor Jeffrey Pearson
Professor Christopher Ward
Functional Dyspepsia2016
Mark Turner
Dr Vinciane Saint-Criq
Waseema Patel
Salam Ibrahim
Dr Burns Verdon
et al.
Hypercapnia Modulates cAMP Signalling and Cystic Fibrosis Transmembrane Conductance Regulator-dependent Anion and Fluid Secretion in Airway Epithelia2016
Dr James Garnett
Dr Georgina Carr
Jason Powell
Dr Malcolm Brodlie
Professor Christopher Ward
et al.
Hyperglycaemia and Pseudomonas aeruginosa acidify cystic fibrosis airway surface liquid by elevating epithelial monocarboxylate transporter 2 dependent lactate-H+ secretion2016
Professor Christopher Ward
Emeritus Professor Nick Europe-Finner
Dr Malcolm Brodlie
IL-22 exacerbates weight loss in a murine model of chronic pulmonary Pseudomonas aeruginosa infection2016
Professor Christopher Ward
Inhaled corticosteroid normalizes some but not all airway vascular remodeling in COPD2016
Dr Hafez Al-momani
Dr Christopher Stewart
Rhys Jones
Amaran Krishnan
Dr Andrew Robertson
et al.
Microbiological profiles of sputum and gastric juice aspirates in Cystic Fibrosis patients2016
Shameem Sultanali Ladak
Professor Christopher Ward
Professor Simi Ali
MiRNA-200b Inhibits Epithelial-Mesenchymal Transition in TGF-b1 Induced Human Bronchial Epithelial Cells.2016
Professor Christopher Ward
Mucosal Cytokines In Asthmatic Bronchoalveolar Lavage (bal) Fluid Reflect Systemic Inflammation And Disease Severity2016
Professor Christopher Ward
Professor Anthony De Soyza
Multidimensional severity assessment in bronchiectasis: an analysis of seven European cohorts2016
Professor Christopher Ward
Professor Anthony De Soyza
Multidimensional Severity Assessment in Bronchiectasis-An Analysis of 7 European Cohorts2016
Christopher Cole
Dr Sonya Carnell
Kasim Jiwa
Dr Jodie Birch
Dr Katy Hester
et al.
Neutrophil vascular endothelial growth factor (VEGF) as a driving force for angiogenesis in bronchiectasis?2016
Dr Jodie Birch
Stella Victorelli
Rhys Anderson
Kasim Jiwa
Dr Elizabeth Moisey
et al.
Telomere Dysfunction and Senescence-associated Pathways in Bronchiectasis2016
Professor Christopher Ward
Professor Jeffrey Pearson
The Potential Role of Aspiration in the Asthmatic Airway Response2016
Shameem Ladak
Professor Christopher Ward
Professor Simi Ali
The potential role of microRNAs in lung allograft rejection2016
Jason Powell
Dr James Garnett
Dr Bernard Verdon
Emerita Professor Janet Wilson
Professor Jeffrey Pearson
et al.
A Human in Vitro Model of the Subglottic Airway2015
Emeritus Professor Nick Europe-Finner
Vicky Ryan
Therese Small
Dr James Lordan
Professor Andrew Fisher
et al.
A randomised controlled trial of azithromycin therapy in Bronchiolitis Obliterans Syndrome (BOS) post lung transplantation 2015
Dr James Garnett
Dr Michael Gray
Dr Malcolm Brodlie
Professor Christopher Ward
Airway epithelial cells secrete bicarbonate in response to acidic by-products of pseudomonas aeruginosa metabolism2015
Professor Anthony De Soyza
Dr James Lordan
Professor Jeffrey Pearson
Professor Christopher Ward
Azithromycin Attenuates Release Of Bile Acid-Mediated Neutrophilic And Remodeling Factors From Human Bronchial Epithelial Cells2015
Professor Anthony De Soyza
Dr James Lordan
June Pearson
Professor Christopher Ward
Azithromycin Attenuates Release of Bile Acid-Mediated Neutrophilic and Remodelling Factors from Human Bronchial Epithelial Cells2015
Dr Malcolm Brodlie
Ali Aseeri
Dr James Lordan
Dr Andrew Robertson
Dr Michael McKean
et al.
Bile acid aspiration in people with cystic fibrosis before and after lung transplantation2015
Professor Anthony De Soyza
Dr James Lordan
Professor Jeffrey Pearson
Professor Christopher Ward
Bile Acids Cause Direct Inflammation And Injury And Worsen Acid Induced Injury In The Pulmonary Epithelium2015
Professor Anthony De Soyza
Dr James Lordan
Professor Jeffrey Pearson
Professor Christopher Ward
Bile Acids Cause Direct Inflammation and Injury and Worsen Acid Induced Injury in the Pulmonary Epithelium2015
Professor Christopher Ward
Describing the Microbiome in the Asthmatic Airway2015
Professor Christopher Ward
Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction2015
Professor Christopher Ward
Hiatal hernias are correlated with increased severity of non-cystic fibrosis bronchiectasis2015
Shameem Sultanali Ladak
Professor Christopher Ward
Professor Simi Ali
MicroRNA-200b represses TGF-β1 induced EMT in BEAS-2B and primary bronchial epithelial cells2015
Professor Christopher Ward
'To measure is to know' (Lord Kelvin)2015
Professor Christopher Ward
A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial-mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study2014
Rhys Jones
Amaran Krishnan
Professor Jeffrey Pearson
Professor John Simpson
Professor Michael Griffin
et al.
Characterisation of Reflux and Aspiration in Idiopathic Pulmonary Fibrosis; An Integrated Approach2014
Professor Christopher Ward
Importance of epithelial mesenchymal transition (EMT) in COPD and asthma2014
Dr Ali Anwar
Professor Anthony De Soyza
Dr Sylvia Worthy
Emeritus Professor Nick Europe-Finner
Dr James Lordan
et al.
Lack of association between KIR and HLA-C type and susceptibility to idiopathic bronchiectasis2014
Monika Suwara
Dr Bart Vanaudenaerde
Dr Nicola Green
Professor Christopher Ward
Dr Lee Borthwick
et al.
Mechanistic differences between phenotypes of chronic lung allograft dysfunction after lung transplantation2014
Gemma Crossfield
Amaran Krishnan
Dr Iain Brownlee
Professor Christopher Ward
Professor Jeffrey Pearson
et al.
Overweight and obesity challenges in the Cystic Fibrosis population - a need for revision in nutritional advice?2014
Shameem Sultanali Ladak
Professor Simi Ali
Professor Christopher Ward
The potential role of miRNA-200b in the development of Bronchiolitis obliterans syndrome2014
Dr Shruti Parikh
Dr Andrew Robertson
Dr Malcolm Brodlie
Emeritus Professor Nick Europe-Finner
Professor Christopher Ward
et al.
Are the enzymatic methods currently being used to measure bronchoalveolar lavage bile salt levels fit for purpose?2013
Professor Michael Griffin
Dr Andrew Robertson
Dr Iain Brownlee
Rachel Stovold
Dr Malcolm Brodlie
et al.
Aspiration and Allograft Injury Secondary to Gastroesophageal Reflux Occur in the Immediate Post-Lung Transplantation Period (Prospective Clinical Trial)2013
Dr James Garnett
Dr Michael Gray
Dr Malcolm Brodlie
Professor Christopher Ward
Erin Baker
et al.
Elevated Paracellular Glucose Flux across Cystic Fibrosis Airway Epithelial Monolayers Is an Important Factor for Pseudomonas aeruginosa Growth2013
Amaran Krishnan
Dr Malcolm Brodlie
Emeritus Professor Nick Europe-Finner
Professor Michael Griffin
Dr Ian Forrest
et al.
Identical Biofilm Forming Strains of Pseudomonas aeruginosa Occur in Lung Allograft BAL and Gastric Juice from CF Patients with Gastro Oesophageal Reflux2013
Professor Christopher Ward
Professor Simi Ali
Identification of biomolecular marker of chronic lung allograft rejection2013
Rhys Jones
Amaran Krishnan
Dr Ian Forrest
Professor Christopher Ward
Arul Immanuel
et al.
Initial Experience of an Aerodigestive Multidisciplinary Team2013
Professor Christopher Ward
Dr James Lordan
Dr Robert Rutherford
Non-cystic fibrosis bronchiectasis2013
Dr Malcolm Brodlie
Professor Christopher Ward
Emeritus Professor Nick Europe-Finner
Novel T helper cell responses against Pseudomonas aeruginosa in healthy individuals and patients with cystic fibrosis2013
Gemma Crossfield
Vicki Strugala
Professor Christopher Ward
Professor Jeffrey Pearson
Pepsin detection despite the use of acid suppressant medication in patients with airway reflux related chronic cough2013
Dr Ali Anwar
Dr Sylvia Worthy
Professor Stephen Bourke
Dr James Lordan
Emeritus Professor Nick Europe-Finner
et al.
Phenotyping adults with non-cystic fibrosis bronchiectasis: A prospective observational cohort study2013
Professor Christopher Ward
Recent advances in understanding inflammation and remodeling in the airways in chronic obstructive pulmonary disease2013
Professor Christopher Ward
Recent advances in understanding inflammation and remodeling in the airways in chronic obstructive pulmonary disease2013
Jen Birch
Dr Gavin Johnson
Professor Christopher Ward
Dr John Taylor
Emeritus Professor Nick Europe-Finner
et al.
Small Airway Epithelial Cell Senescence Present in COPD and Bronchiectasis?2013
Dr Lee Borthwick
Emeritus Professor Nick Europe-Finner
Dr Rahul Mahida
Andrew Walker
Aaron Gardner
et al.
TNFα From Classically Activated Macrophages Accentuates Epithelial to Mesenchymal Transition in Obliterative Bronchiolitis2013
Emeritus Professor Nick Europe-Finner
Therese Small
Vicky Ryan
Dr James Lordan
Professor Andrew Fisher
et al.
A Randomised Controlled Trial of Azithromycin Therapy in Bronchiolitis Obliterans Syndrome (BOS) Post Lung Transplantation2012
Dr Andrew Robertson
Amaran Krishnan
Professor Christopher Ward
Professor Jeffrey Pearson
Therese Small
et al.
Anti-reflux surgery in lung transplant recipients: outcomes and effects on quality of life2012
Ali Aseeri
Dr Malcolm Brodlie
Dr James Lordan
Emeritus Professor Nick Europe-Finner
Professor Jeffrey Pearson
et al.
Bile Acids Are Present in the Lower Airways of People with Cystic Fibrosis2012
Rachel Stovold
Professor Jeffrey Pearson
Professor Christopher Ward
Chronic Cough: Relationship Between Microaspiration, Gastroesophageal Reflux, and Cough Frequency2012
Professor Christopher Ward
Epithelial Mesenchymal Transition (EMT) in Chronic Obstructive Pulmonary Disease (COPD) Airways is Attenuated by Inhaled Corticosteroids (ICS)2012
Dr Malcolm Brodlie
Emeritus Professor Nick Europe-Finner
Dr James Lordan
Professor Christopher Ward
Interleukin-17 and Cystic Fibrosis Lung Disease2012
Dr Aaron Ions Gardner
Professor Andrew Fisher
Christine Richter
Grace Johnson
Dr Elizabeth Moisey
et al.
The Critical Role of TAK1 in Accentuated Epithelial to Mesenchymal Transition in Obliterative Bronchiolitis after Lung Transplantation2012
Dr Lee Borthwick
Dr John Perry
Dr Malcolm Brodlie
Professor Christopher Ward
Katherine Gould
et al.
Pseudomonas aeruginosa accentuates epithelial-to-mesenchymal transition in the airway2011
Dr Malcolm Brodlie
Dr James Lordan
Professor Christopher Ward
Can cells other than Th17 lymphocytes be important sources of IL-17 in the lungs?2011
Dr Malcolm Brodlie
Dr James Lordan
Professor Christopher Ward
Ceramide and cystic fibrosis lung disease2011
Professor Christopher Ward
Infection and remodelling: a 21st century model of bronchiectasis?2011
Dr Malcolm Brodlie
Dr Michael McKean
Dr Amy Anderson
Dr Catharien Hilkens
Professor Andrew Fisher
et al.
Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease2011
Professor Christopher Ward
Assessment of airway inflammation using sputum, BAL, and endobronchial biopsies in current and ex-smokers with established COPD2010
Dr Malcolm Brodlie
Dr Michael McKean
Dr Joseph Gray
Professor Andrew Fisher
Emeritus Professor Nick Europe-Finner
et al.
Ceramide is Increased in the Lower Airway Epithelium of People with Advanced Cystic Fibrosis Lung Disease2010
Dr Ali Anwar
Professor Stephen Bourke
Dr Peter Middleton
Professor Christopher Ward
Dr Robert Rutherford
et al.
Efficacy of nebulised colomycin in patients with non-cystic fibrosis bronchiectasis colonised with Pseudomonas aeruginosa2010
Dr Iain Brownlee
Ali Aseeri
Professor Christopher Ward
Professor Jeffrey Pearson
From gastric aspiration to airway inflammation2010
Dr Lee Borthwick
Marta Gorowiec
Dr Malcolm Brodlie
Professor Christopher Ward
Dr James Lordan
et al.
Inflammation and Epithelial to Mesenchymal Transition in Lung Transplant Recipients: Role in Dysregulated Epithelial Wound Repair2010
Dr Andrew Robertson
Professor Christopher Ward
Therese Small
Dr James Lordan
Professor Andrew Fisher
et al.
Longitudinal changes in gastro-oesophageal reflux from three months to six months post lung transplantation2010
Dr Andrew Robertson
Professor Christopher Ward
Professor Jeffrey Pearson
Emeritus Professor Nick Europe-Finner
Professor John Dark
et al.
Lung Transplantation, Gastroesophageal Reflux, and Fundoplication2010
Dr Ian Forrest
Professor Christopher Ward
Macrolide antibiotics and the airway: antibiotic or non-antibiotic effects?2010
Dr Malcolm Brodlie
Dr Michael McKean
Dr John Perry
Dr Burns Verdon
Dr Michael Gray
et al.
Primary bronchial epithelial cell culture from explanted cystic fibrosis lungs2010
Dr Don Reid
Professor Christopher Ward
Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease2010
Professor Christopher Ward
Vicky Ryan
Professor Jeffrey Pearson
Susceptibility to Exacerbation in COPD2010
Dr Lee Borthwick
Dr Malcolm Brodlie
Professor Christopher Ward
Dr John Perry
Emeritus Professor Nick Europe-Finner
et al.
The M1 macrophage phenotype accentuates TGF-beta 1 driven epithelial to mesenchymal transition (EMT) via the secretion of TNF alpha2010
Dr Andrew Robertson
Dr Jonathan Shenfine
Professor Christopher Ward
Professor Jeffrey Pearson
Professor John Dark
et al.
A Call for Standardization of Antireflux Surgery in the Lung Transplantation Population2009
Dr Malcolm Brodlie
Dr Catharien Hilkens
Professor Christopher Ward
Airway epithelial cells as guardians of immune homeostasis?2009
Dr Andrew Robertson
Professor Michael Griffin
Professor Christopher Ward
Professor Jeffrey Pearson
Professor John Dark
et al.
Aspiration in the Immediate Post Lung Transplantation Period2009
Dr Andrew Robertson
Professor Christopher Ward
Professor Jeffrey Pearson
Professor Andrew Fisher
Dr James Lordan
et al.
Aspiration Secondary to Gastro-Oesophageal Reflux but not Duodenal Reflux Occurs in the Immediate Post Lung Transplantation Period2009
Dr Ian Forrest
Professor Christopher Ward
Vicky Ryan
Dr Gavin Johnson
Dr James Lordan
et al.
Bronchalveolar Lavage Neutrophilia and MMP-9 at 3 Months Post Lung Transplantation May Predict the Development of BOS2009
Professor Christopher Ward
Julie Diboll
Professor Andrew Fisher
Dr Malcolm Brodlie
Dr James Lordan
et al.
Bronchial epithelial cells cultured from clinically stable lung allograft patients promote the development of macrophages from monocytes rather than dendritic cells2009
Dr Malcolm Brodlie
Dr Michael McKean
Professor Andrew Fisher
Emeritus Professor Nick Europe-Finner
Dr James Lordan
et al.
Ceramide is increased and associated with neutrophilic inflammation in the lower airway epithelium of people with cystic fibrosis2009
Dr Lee Borthwick
Dr Sean Parker
Kate Brougham
Marta Gorowiec
Professor Christopher Ward
et al.
Epithelial to mesenchymal transition (EMT) and airway remodelling after human lung transplantation2009
Professor Christopher Ward
Professor Jeffrey Pearson
Therese Small
Dr James Lordan
Professor Andrew Fisher
et al.
Longitudinal changes in gastro-oesophageal reflux from 3 months to 6 months after lung transplantation2009
Dr Lee Borthwick
Dr Malcolm Brodlie
Professor Christopher Ward
Dr James Lordan
Professor John Kirby
et al.
Pro-inflammatory Cytokines IL-1 beta and TNT alpha, but Not IL-8, Cause Aberrant Lung Epithelial Wound Repair Via TGF-beta 1 Driven Epithelial to Mesenchymal Transition (EMT)2009
Dr Malcolm Brodlie
Dr Michael McKean
Professor Andrew Fisher
Emeritus Professor Nick Europe-Finner
Dr James Lordan
et al.
Reticular basement membrane thickening in end-stage cystic fibrosis lung disease2009
Dr Andrew Robertson
Professor Michael Griffin
Professor Jeffrey Pearson
Dr Ian Forrest
Professor John Dark
et al.
Targeting Allograft Injury and Inflammation in the Management of Post-Lung Transplant Bronchiolitis Obliterans Syndrome2009
Rachel Stovold
Dr Ian Forrest
Dr James Lordan
Professor Andrew Fisher
Professor John Dark
et al.
Temporal Patterns of Lung Pepsin Levels in Allografts Suggest Aspiration Is an Ongoing Injury, Which Can Occur Early Following Lung Transplantation2009
Dr Sean Parker
Dr Lee Borthwick
Professor Christopher Ward
Dr James Lordan
Emeritus Professor Nick Europe-Finner
et al.
Airway epithelial cell senescence in the lung allograft2008
Professor Christopher Ward
Angiogenesis: A potentially critical part of remodelling in chronic airway diseases?2008
Dr Rachel Anderson
Professor Christopher Ward
Dr Ian Forrest
Dr James Lordan
Emeritus Professor Nick Europe-Finner
et al.
Antimicrobial Peptides in Lung Transplant Recipients with Bronchiolitis Obliterans Syndrome2008
Adillah Binti Yusof
Dr Ian Forrest
Emeritus Professor Nick Europe-Finner
Therese Small
Debra Jones
et al.
Azithromycin attenuates effects of lipopolysaccharide on lung allograft bronchial epithelial cells2008
Dr Ian Forrest
Emeritus Professor Nick Europe-Finner
Dr Gavin Johnson
Therese Small
Professor Andrew Fisher
et al.
Azithromycin attenuates lipopolysaccharide-mediated release of interleukin-8 and GM-CSF from primary bronchial epithelial cells derived from stable lung transplant recipients2008
Professor Christopher Ward
Bronchodilator reversibility, airway eosinophilia and anti-inflammatory effects of inhaled fluticasone in COPD are not related2008
Rachel Stovold
Emeritus Professor Nick Europe-Finner
Professor Andrew Fisher
Dr James Lordan
Professor Jeffrey Pearson
et al.
Does pepsin in gastric juice aspirated into the lung allograft stimulate mucus hypersecretion?2008
Dr Ali Anwar
Professor Stephen Bourke
Dr Peter Middleton
Professor Christopher Ward
Dr Robert Rutherford
et al.
Effects of long-term low-dose azithromycin in patients with non-CF bronchiectasis2008
Professor Christopher Ward
Innate immune activation in neutrophilic asthma2008
Rachel Stovold
Dr Ian Forrest
Dr James Lordan
Professor Andrew Fisher
Emeritus Professor Nick Europe-Finner
et al.
Longitudinal assessment of pepsin levels in lung allografts suggests aspiration is an ongoing injury, which can occur early following lung transplantation2008
Marta Gorowiec
Dr Lee Borthwick
Marcin Pekalski
Dr James Lordan
Emeritus Professor Nick Europe-Finner
et al.
Oxidative stress induces epithelial to mesenchymal transition in human lung epithelial cells through transforming groeth factor beta and integrin beta6-dependent mechanism2008
Dr Lee Borthwick
Kate Brougham
Professor Christopher Ward
Dr James Lordan
Professor John Kirby
et al.
Pro-inflammatory cytokines dysregulate lung epithelial wound repair via epithelial to mesenchymal transition2008
Dr Andrew Robertson
Professor Michael Griffin
Professor Christopher Ward
Professor Jeffrey Pearson
Anne Bredenoord
et al.
Qualitative and quantitative assessments of aspiration in the immediate post-lung transplantation period2008
Rachel Stovold
Professor Jeffrey Pearson
Professor Christopher Ward
Relationships between micro-aspiration, gastro-oesophageal reflux and cough in chronic cough subjects2008
Emeritus Professor Mike Sir Michael Rawlins
Dr Ian Forrest
Emeritus Professor Nick Europe-Finner
Therese Small
Debra Jones
et al.
Simvastatin attenuates release of neutrophilic and remodeling factors from primary bronchial epithelial cells derived from stable lung transplant recipients2008
Dr Ian Forrest
Emeritus Professor Nick Europe-Finner
Therese Small
Professor Andrew Fisher
Emeritus Professor Tim Cawston
et al.
Simvastatin potentially decreases neutrophilic inflammation and remodelling in the transplanted airway2008
Dr Malcolm Brodlie
Dr Michael McKean
Dr John Perry
Anne Nicholson
Professor Jeffrey Pearson
et al.
The culture of primary bronchial epithelial cells from the lungs of people with cystic fibrosis removed at the time of transplantation: a model to study cystic fibrosis lung disease2008
Dr Lee Borthwick
Sally Maloney
Dr Rachel Anderson
Professor Christopher Ward
Dr James Lordan
et al.
Transforming growth factor beta 1 suppresses secretory leucoprotease inhibitor release in response to infection in lung epithelial cells2008
Dr Lee Borthwick
Dr Sean Parker
Marta Gorowiec
Professor Christopher Ward
Dr James Lordan
et al.
Tumour necrosis factor-α accentuates transforming growth factor-β driven epithelial to mesenchymal transition (EMT) in airway epithelial cells from lung transplant recipients2008
Professor Christopher Ward
Vascular remodelling in asthma2008
Professor Christopher Ward
Airway cell and cytokine changes in early asthma deterioration after inhaled corticosteroid reduction2007
Dr Laura Mackay
Professor Christopher Ward
Dr James Lordan
Professor Andrew Fisher
Emeritus Professor Nick Europe-Finner
et al.
Alveolar septae in severe end-stage emphysema show morphological evidence of dysregulated mesenchymal cell proliferation and loss of microvascularity2007
Dr Ian Forrest
Professor Christopher Ward
Emeritus Professor Nick Europe-Finner
Debra Jones
Professor Andrew Fisher
et al.
Effect of azithromycin on primary bronchial epithelial cells derived from stable lung allografts2007
Professor Christopher Ward
Effects of inhaled fluticasone on angiogenesis and vascular endothelial growth factor in asthma2007
Professor Christopher Ward
Nonpharmacological and pharmacological interventions to prevent or reduce airway remodelling2007
Marta Gorowiec
Dr Sean Parker
Dr Lee Borthwick
Professor Christopher Ward
Dr James Lordan
et al.
Oxidative stress increases transforming growth factor-beta expression and drives epithelial to mesenchymal transition in human lung epithelial cells2007
Rachel Stovold
Dr Ian Forrest
Emeritus Professor Nick Europe-Finner
Professor John Dark
Professor Jeffrey Pearson
et al.
Pepsin, a biomarker of gastric aspiration in lung allografts: A putative association with rejection2007
Rachel Stovold
Dr Ian Forrest
Emeritus Professor Nick Europe-Finner
Julie Smith
Professor John Dark
et al.
Pepsin, a biomarker of gastric aspiration in lung allografts: a putative association with rejection2007
Dr Sean Parker
Professor Christopher Ward
Dr James Lordan
Emeritus Professor Nick Europe-Finner
Dr Gabriele Saretzki
et al.
Stress-induced premature senescence in airway epithelium and accelerated lung allograft aging2007
Dr Sean Parker
Marta Gorowiec
Dr Lee Borthwick
Dr James Lordan
Professor Christopher Ward
et al.
Transforming growth factor beta (TGF beta) induces cellular senescence in primary bronchial epithelial cells: A possible role in airway remodelling2007
Professor Barbara Hanratty
Professor Carl May
Professor Christopher Ward
Doctor's understanding of palliative care2006
Dr Lee Borthwick
Professor Christopher Ward
Dr James Lordan
Emeritus Professor Nick Europe-Finner
Professor Andrew Fisher
et al.
Epithelial mesencymal transition occurs in primary airway epithelial cells in response to transforming growth factor-beta and epidermal growth factor2006
Rachel Stovold
Dr Ian Forrest
Dr Desmond Murphy
Emeritus Professor Nick Europe-Finner
Professor Andrew Fisher
et al.
Evidence of increased gastric aspiration in acute lung allograft rejection2006
Dr Ian Forrest
Professor Christopher Ward
Dr Desmond Murphy
David Jones
Dr James Lordan
et al.
Hepatocyte growth factor - A link between neutrophilic inflammation and BOS?2006
Professor Christopher Ward
Increased vascular endothelial growth factor and receptors - Relationship to angiogenesis in asthma2006
Dr Lee Borthwick
Dr Sean Parker
Professor Christopher Ward
Emeritus Professor Nick Europe-Finner
Dr James Lordan
et al.
Oxidative stress induces epithelial to mesenchymal transition in bronchial epithelial cells: A possible role in airway remodelling2006
Dr Sean Parker
Professor Christopher Ward
Dr Fiona Black
Dr James Lordan
Emeritus Professor Nick Europe-Finner
et al.
Premature senescence of airway epithelial cells: A possible role in airway remodelling after human lung transplantation2006
Professor Christopher Ward
Dr Ian Forrest
Professor David Jones
Dr Gary Pritchard
Rachel Stovold
et al.
The phosphodiesterase type IV (PDE IV) inhibitor cilomilast decreases pro-inflammatory cytokine production from primary bronchial epithelial cells derived from lung transplant recipients2006
Dr Desmond Murphy
Professor Christopher Ward
David Jones
Rachel Stovold
Professor Andrew Fisher
et al.
The phosphodiesterase type IV inhibitor cilomilast decreases pro-inflammatory cytokine production from primary bronchial epithelial cells in lung transplantation patients2006
Dr Lee Borthwick
Professor Christopher Ward
Dr James Lordan
Emeritus Professor Nick Europe-Finner
Professor Andrew Fisher
et al.
Tumour necrosis factor-alpha accentuates transforming growth factor-beta driven epithelial to mesenchymal transition in lung epithelial cells2006
Professor Christopher Ward
Professor Anthony De Soyza
Professor Andrew Fisher
Emeritus Professor Nick Europe-Finner
A descriptive study of small airway reticular basement membrane thickening in clinically stable lung transplant recipients2005
Professor Christopher Ward
Airway wall remodelling: The influence of corticosteroids2005
Professor Christopher Ward
Suzanne Scorfield
Phil Botha
Professor John Dark
Emeritus Professor Nick Europe-Finner
et al.
Association between the genotype of the TNF locus and acute rejection following lung transplant2005
Professor Christopher Ward
Dr Robert Rutherford
Professor Andrew Fisher
Dr James Lordan
Professor John Dark
et al.
Azithromycin reverses airflow obstruction in established bronchiolitis obliterans syndrome2005
Professor Christopher Ward
Dr Ian Forrest
Professor Andrew Fisher
Dr James Lordan
Emeritus Professor Nick Europe-Finner
et al.
Azithromycin reverses airflow obstruction in established bronchiolitis obliterans syndrome (BOS) following lung transplantation2005
Professor Christopher Ward
Bronchial hyperresponsiveness and the bronchiolitis obliterans syndrome after lung transplantation2005
Dr Ian Forrest
Dr James Lordan
Dr Gary Pritchard
Professor David Jones
Dr Helen Robertson
et al.
Epithelial to mesenchymal transition in clinically stable lung transplant recipients2005
Dr Lindsay Nicholson
Professor Christopher Ward
Professor John Dark
Dr Peter Middleton
Emeritus Professor Nick Europe-Finner
et al.
Genetic polymorphisms and bronchiolitis obliterans syndrome post lung transplantation2005
Professor Christopher Ward
Dr Helen Robertson
Dr Ian Forrest
Dr James Lordan
Denis Murphy
et al.
Hypothesis: Epithelial-to-mesenchymal transition is a common cause of chronic allograft failure2005
Professor Christopher Ward
Vicky Ryan
Inter-relationships between airway inflammation, reticular basement membrane thickening and bronchial hyper-reactivity to methacholine in asthma; a systematic bronchoalveolar lavage and airway biopsy analysis2005
Professor Christopher Ward
Longitudinal comparisons of lymphocytes and subtypes between airway wall and bronchoalveolar lavage after human lung transplantation2005
Professor Christopher Ward
Dr Ian Forrest
Dr Iain Brownlee
Professor Jeffrey Pearson
Professor John Dark
et al.
Pepsin like activity in bronchoalveolar lavage fluid is suggestive of gastric aspiration in lung allografts2005
Professor Christopher Ward
Dr Ian Forrest
Dr Helen Robertson
Emeritus Professor Tim Cawston
Professor Andrew Fisher
et al.
Phenotype of airway epithelial cells suggests epithelial to mesenchymal cell transition in clinically stable lung transplant recipients2005
Dr Ian Forrest
Dr Desmond Murphy
Professor Christopher Ward
David Jones
Professor Kate Gould
et al.
Primary airway epithelial cell culture from lung transplant recipients2005
Dr Ian Forrest
Professor Christopher Ward
Emeritus Professor Nick Europe-Finner
Professor Andrew Fisher
Emeritus Professor Tim Cawston
et al.
The potential role of interleukin-17 in airway inflammation and remodelling in post-transplant obliterative bronchiolitis2005
Professor Bob Anderson
Dr Ian Forrest
Professor Christopher Ward
Dr Gavin Johnson
Dr James Lordan
et al.
The pulmonary innate immune response to pseudomonas aeruginosa infection in human lung transplant recipients2005
Professor Christopher Ward
Dr Iain Brownlee
Dr Ian Forrest
Dr Thomas Ward
Dr Desmond Murphy
et al.
Clinically silent gastric aspiration is common in lung allografts2004
Dr Ian Forrest
Dr James Lordan
Dr Helen Robertson
Emeritus Professor Tim Cawston
Professor John Dark
et al.
Epithelial to mesenchymal transition in clinically stable lung transplantation2004
Dr Ian Forrest
Professor Christopher Ward
Emeritus Professor Nick Europe-Finner
Dr Peter Middleton
Genotypic risk factors for the development of the bronchiolitis oblitererans syndrome (BOS) after lung transplantation2004
Dr Ian Forrest
Professor Christopher Ward
Emeritus Professor Tim Cawston
Emeritus Professor Nick Europe-Finner
Dr James Lordan
et al.
IL-17 stimulates IL-8 release in primary epithelial cell cultures derived from lung allografts2004
Dr Iain Brownlee
Professor Christopher Ward
Dr Ian Forrest
Dr Gary Pritchard
Professor John Dark
et al.
Pepsin detection in the lungs of transplant patients: Evidence of gastric refluxate2004
Professor Christopher Ward
Professor Anthony De Soyza
Professor Andrew Fisher
Emeritus Professor Nick Europe-Finner
Reticular basement membrane thickening in airways of lung transplant recipients is not affected by inhaled corticosteroids2004
Professor Christopher Ward
Exhaled nitric oxide continues to reflect airway hyperresponsiveness and disease activity in inhaled corticosteroid-treated adult asthmatic patients2003
Professor Christopher Ward
Possible anti-inflammatory effect of salmeterol against interleukin-8 and neutrophil activation in asthma in vivo2003
Professor Christopher Ward
Dr Ian Forrest
Professor Anthony De Soyza
Professor Andrew Fisher
Emeritus Professor Nick Europe-Finner
et al.
Preliminary findings of quorum signal molecules in clinically stable lung allograft recipients2003
Professor Christopher Ward
Revision of BTS guidelines for treatment of asthma [1] (multiple letters)2003
Professor Christopher Ward
Dr Ian Forrest
Professor Anthony De Soyza
Professor Andrew Fisher
Emeritus Professor Nick Europe-Finner
et al.
The presence of quorum-sensing signal molecules in clinically stable lung2003
Professor Christopher Ward
Addition of inhaled corticosteroids to systemic immunosuppression after lung transplantation: a double-blind, placebo-controlled trial [see comment]2002
Professor Christopher Ward
Airway inflammation, basement membrane thickening and bronchial hyperresponsiveness in asthma2002
Professor Christopher Ward
Dr Gary Pritchard
Emeritus Professor Drew Rowan
Emeritus Professor Tim Cawston
Emeritus Professor Nick Europe-Finner
et al.
Co-localisation of MMP-9 with neutrophils in stable lung transplant recipients - A potential role in Bronchiolitis Obliterans2002
Professor Barbara Hanratty
Professor Carl May
Professor Christopher Ward
Doctors' perceptions of palliative care for heart failure: focus group study2002
Professor Christopher Ward
European Community Respiratory Health Survey calibration project of dosimeter driving pressures2002
Professor Christopher Ward
Increased soluble CD14 in bronchoalveolar lavage fluid of stable lung transplant recipients2002
Professor Christopher Ward
Inhaled corticosteroid dosage in asthma - Reply2002
Professor Christopher Ward
Dr Douglas Reid
PD20 to methacholine is predicted by airway inflammation and remodelling: A systematic, longitudinal, steroid intervention study of airway biopsy (Ebb) and BAL parameters2002
Professor Christopher Ward
Professor Anthony De Soyza
Andrew Fisher
Dr Gary Pritchard
Emeritus Professor Nick Europe-Finner
et al.
Small airway reticular basement membrane (RBM) thickening in clinically stable lung transplant recipients (SLTR) is not affected by three months treatment with inhaled corticosteroids (ICS)2002
Professor Christopher Ward
Professor Anthony De Soyza
Professor Andrew Fisher
Emeritus Professor Nick Europe-Finner
The presence of quorum sensing signal molecules in clinically stable lung allograft recipients suggests bacterial biofilm biology2002
Professor Christopher Ward
Bronchoalveolar lavage macrophage and lymphocyte phenotypes in lung transplant recipients2001
Professor Christopher Ward
Effect of a Long-Acting β2-Agonist over Three Months on Airway Wall Vascular Remodeling in Asthma2001
Professor Christopher Ward
Eg-1 positive eosinophils in asthma - Reply2001
Professor Christopher Ward
Iron overload and nitric oxide-derived oxidative stress following lung transplantation2001
Professor Christopher Ward
Normally suppressing CD40 coregulatory signals delivered by airway macrophages to TH2 lymphocytes are defective in patients with atopic asthma2001
Professor Christopher Ward
Reduced airway distensibility, fixed airflow limitation and airway wall remodelling in asthma2001
Professor Christopher Ward
Reduced airway distensibility, fixed airflow limitation, and airway wall remodeling in asthma2001
Professor Christopher Ward
Nan Wang
Airway neutrophilia in stable and bronchiolitis obliterans syndrome patients following lung transplantation2000
Professor Christopher Ward
Bronchoalveolar lavage cellular profiles in lung transplantation: the effect of inhaled corticosteroids2000
Professor Christopher Ward
Bronchoalveolar lavage fluid urea as a measure of pulmonary permeability in healthy smokers2000
Professor Christopher Ward
Post-lung transplant bronchiolitis obliterans syndrome (BOS) is characterized by increased exhaled nitric oxide levels and epithelial inducible nitric oxide synthase2000
Professor Christopher Ward
Airway Vascular Changes in Lung Allograft Recipients1999
Professor Christopher Ward
Modulatory effects of alveolar macrophages on CD4+ T-cell IL-5 responses correlate with IL-1beta, IL-6, and IL-12 production1999