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Lookup NU author(s): Professor Majlinda LakoORCiD,
Professor Miodrag Stojkovic
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
Stem cells are undifferentiated cells that are present in the embryonic, fetal, and adult stages of life and give rise to differentiated cells that make up the building blocks of tissue and organs. Due to their unlimited source and high differentiation potential, stem cells are considered as potentially new therapeutic agents for the treatment of infertility. Stem cells could be stimulated in vitro to develop various numbers of specialized cells including male and female gametes suggesting their potential use in reproductive medicine. During past few years a considerable progress in the derivation of male germ cells from pluripotent stem cells has been made. In addition, stem cell-based strategies for ovarian regeneration and oocyte production have been proposed as future clinical therapies for treating infertility in women. In this review, we summarized current knowledge and present future perspectives and challenges regarding the use of stem cells in reproductive medicine.
Author(s): Volarevic V, Bojic S, Nurkovic J, Volarevic A, Ljujic B, Arsenijevic N, Lako M, Stojkovic M
Publication type: Review
Publication status: Published
Journal: BioMed Research International
Print publication date: 14/04/2014
Online publication date: 14/04/2014
Acceptance date: 17/03/2014
ISSN (print): 2314-6133
ISSN (electronic): 2314-6141
Publisher: HINDAWI PUBLISHING CORPORATION