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Browsing publications by Professor Majlinda Lako.

Newcastle AuthorsTitleYearFull text
Dr Maria Georgiou
Dr Chunbo Yang
Rob Atkinson
Dr Adriana Buskin
Dr Joseph Collin
et al.
Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patient iPSC-derived retinal pigment epithelium cells2022
Robert Jackson
Dr Maria Georgiou
Catherine Hatton
Dr Jarmila Spegarova
Dr Rachel Queen
et al.
Conjunctival epithelial cells resist productive SARS-CoV-2 infection2022
Ivo Djidrovski
Dr Maria Georgiou
Elena Tasinato
Professor Majlinda Lako
Professor Lyle Armstrong
et al.
Direct transcriptomic comparison of xenobiotic metabolism and toxicity pathway induction of airway epithelium models at an air–liquid interface generated from induced pluripotent stem cells and primary bronchial epithelial cells2022
Dr Maria Georgiou
Alex Chaudhary
Dr Joseph Collin
Dr Rachel Queen
Dr Birthe Hilgen
et al.
Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina2022
Dr Agata Rozanska
Rodrigo Cerna Chavez
Dr Rachel Queen
Dr Joseph Collin
Dr Darin Zerti
et al.
pRB-depleted pluripotent stem cell retinal organoids recapitulate cell state transitions of retinoblastoma development and suggest an important role for pRB in retinal cell differentiation2022
Dr Maria Georgiou
Rob Atkinson
Professor Majlinda Lako
Progressive accumulation of cytoplasmic aggregates in PRPF31 retinal pigment epithelium cells interferes with cell survival2022
Dr Laura Wadkin
Professor Majlinda Lako
Dr Nick Parker
Professor Anvar Shukurov
A mathematical modelling framework for the regulation of intra-cellular OCT4 in human pluripotent stem cells2021
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Professor Francisco Figueiredo
Professor Lyle Armstrong
et al.
A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells2021
Professor Francisco Figueiredo
Dr Jeffry Hogg
Arthur Okonkwo
Dr Gustavo Figueiredo
Professor Majlinda Lako
et al.
A systematic review of cellular therapies for the treatment of limbal stem cell deficiency affecting one or both eyes2021
Dr Marzena Kurzawa-Akanbi
Professor David Steel
Professor Majlinda Lako
Age-related macular degeneration - Biomarkers and therapies2021
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Professor David Steel
Professor Majlinda Lako
et al.
Dissecting the transcriptional and chromatin accessibility heterogeneity of proliferating cone precursors in human retinoblastoma tumours by single cell sequencing- opening pathways to new therapeutic strategies?2021
Dr Darin Zerti
Marina MoyaMolina
Dr Birthe Hilgen
Dr Roman Bauer
Professor Majlinda Lako
et al.
IGFBPs mediate IGF-1’s functions in retinal lamination and photoreceptor development during pluripotent stem cell differentiation to retinal organoids2021
Professor Lyle Armstrong
Dr Joseph Collin
Dr Islam Mostafa
Dr Rachel Queen
Professor Francisco Figueiredo
et al.
In the eye of the storm: SARS-CoV-2 infection and replication at the ocular surface?2021
Dr Laura Wadkin
Dr Sirio Orozco Fuentes
Dr Irina Neganova
Professor Majlinda Lako
Dr Andrew Baggaley
et al.
OCT4 expression in human embryonic stem cells: spatio-temporal dynamics and fate transitions2021
Professor Francisco Figueiredo
Professor Majlinda Lako
Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions2021
Dr Chunbo Yang
Dr Maria Georgiou
Rob Atkinson
Dr Joseph Collin
Professor Lyle Armstrong
et al.
Pre-mRNA Processing Factors and Retinitis Pigmentosa: RNA Splicing and Beyond2021
Professor Majlinda Lako
Professor Francisco Figueiredo
Referral Patterns of Patients with Limbal Stem Cell Deficiency to a Specialized Tertiary Center in the United Kingdom2021
Nik Tzoumas
Dr Dean Hallam
Professor Claire Harris
Professor Majlinda Lako
Professor David Kavanagh
et al.
Revisiting the role of factor H in age-related macular degeneration: Insights from complement-mediated renal disease and rare genetic variants.2021
Ivo Djidrovski
Dr Maria Georgiou
Marina MoyaMolina
Dr Git Chung
Professor Majlinda Lako
et al.
SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells2021
Dr Rachel Queen
Professor Majlinda Lako
Zerti Zerti
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics2021
Dr Sirio Orozco Fuentes
Dr Laura Wadkin
Dr Irina Neganova
Professor Majlinda Lako
Dr Andrew Baggaley
et al.
Spatio-temporal analyses of transcription factor expression and fate transitions in a hESC colony2021
Professor Majlinda Lako
Professor Miodrag Stojkovic
Stem cells and hearing loss2021
Dr Darin Zerti
Dr Birthe Hilgen
Dr Joseph Collin
Professor Lyle Armstrong
Professor Evelyne Sernagor
et al.
Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration2021
Dr Ali Ghareeb
Professor Majlinda Lako
Professor David Steel
Coculture techniques for modeling retinal development and disease, and enabling regenerative medicine2020
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Maria Georgiou
et al.
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface2020
Edvinas Cerniauskas
Dr Marzena Kurzawa-Akanbi
Dr Long Xie
Dr Dean Hallam
Marina Moya Molina
et al.
Complement modulation reverses pathology in Y402H-retinal pigment epithelium cell model of AMD by restoring lysosomal function2020
Dr Darin Zerti
Dr Birthe Hilgen
Majed Felemban
Dr Ali Ghareeb
Dr Min Yu
et al.
Developing a simple method to enhance the generation of cone and rod photoreceptors in pluripotent stem cell‐derived retinal organoids 2020
Dr Jarmila Spegarova
Dr Karin Engelhardt
Dr Helen Griffin
Dr Aneta Mikulasova
Dr Meghan Acres
et al.
Germline TET2 loss-of-function causes childhood immunodeficiency and lymphoma2020
Dr Valeria Chichagova
Dr Gerrit Hilgen
Dr Ali Ghareeb
Madeleine Carter
Professor Evelyne Sernagor
et al.
Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line‐ and method‐dependent2020
Dr Sanja Bojic
Professor Lyle Armstrong
Professor Majlinda Lako
Dr Roman Bauer
Professor Miodrag Stojkovic
et al.
Platform to study intracellular polystyrene nanoplastic pollution and clinical outcomes2020
Dr Ali Ghareeb
Professor Majlinda Lako
Professor Francisco Figueiredo
Recent Advances in Stem Cell Therapy for Limbal Stem Cell Deficiency: A Narrative Review2020
Dr Maria Georgiou
Dr Valeria Chichagova
Dr Birthe Hilgen
Professor Evelyne Sernagor
Professor Lyle Armstrong
et al.
Room temperature shipment does not affect the biological activity of pluripotent stem cell-derived retinal organoids2020
Dr Rachel Queen
Professor Majlinda Lako
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes2020
Dr Laura Wadkin
Dr Sirio Orozco Fuentes
Dr Irina Neganova
Professor Majlinda Lako
Professor Anvar Shukurov
et al.
The recent advances in the mathematical modelling of human pluripotent stem cells2020
Dr Rachel Queen
Dr Simon Cockell
Professor Majlinda Lako
Understanding the complexity of retinal and pluripotent stem cell derived retinal organoids with single cell RNA sequencing: current progress, remaining challenges and future prospectives2020
Dr Adriana Buskin
Professor Majlinda Lako
AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+/− iPSC-Derived RPE Cells2019
Dr Carla Jackson
Dr Roman Bauer
Dr Joseph Collin
Dr Birthe Hilgen
Dr Darin Zerti
et al.
An integrated transcriptional analysis of the developing human retina2019
Dr Joseph Collin
Dr Darin Zerti
Dr Rachel Queen
Dr Roman Bauer
Dr Jonathan Coxhead
et al.
CRX Expression in Pluripotent Stem Cell‐Derived Photoreceptors Marks a Transplantable Subpopulation of Early Cones2019
Majed Felemban
Dr Birthe Hilgen
Dr Darin Zerti
Dr Nicola Hunt
Dr Dean Hallam
et al.
Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids2019
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Raf Hussain
et al.
Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina2019
Dr Valeria Chichagova
Dr Birthe Hilgen
Majed Felemban
Dr Maria Georgiou
Professor Lyle Armstrong
et al.
Differentiation of Retinal Organoids from Human Pluripotent Stem Cells2019
Dr Laura Wadkin
Dr Sirio Orozco Fuentes
Dr Irina Neganova
Dr Sanja Bojic
Dr Alex Laude
et al.
Seeding hESCs to achieve optimal colony clonality2019
Dr Carla Jackson
Dr Joseph Collin
Dr Rachel Queen
Dr Birthe Hilgen
Dr Darin Zerti
et al.
Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences2019
Dr Sai Kolli
Dr Sanja Bojic
Dr Ali Ghareeb
Dr Marzena Kurzawa-Akanbi
Professor Francisco Figueiredo
et al.
The Role of Nerve Growth Factor in Maintaining Proliferative Capacity, Colony‐Forming Efficiency, and the Limbal Stem Cell Phenotype2019
Dr Osagie Izuogu
Dr Carla Mellough
Dr Joseph Collin
Dr Richard Gallon
Francesco Kumara Mastrorosa
et al.
Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular2018
Dr Sanja Bojic
Dr Dean Hallam
Nuno Alcada
Dr Ali Ghareeb
Dr Rachel Queen
et al.
CD200 expression marks a population of quiescent limbal epithelial stem cells with holoclone forming ability2018
Dr Valeria Chichagova
Dr Dean Hallam
Dr Joseph Collin
Dr Darin Zerti
Dr Birthe Hilgen
et al.
Cellular regeneration strategies for macular degeneration: past, present and future2018
Dr Laura Wadkin
Dr Sirio Orozco Fuentes
Dr Irina Neganova
Dr Alex Laude
Professor Majlinda Lako
et al.
Correlated random walks of human embryonic stem cells in vitro2018
Dr Charlie Osei-Bempong
Dr Ali Ghareeb
Professor Majlinda Lako
Professor Francisco Figueiredo
Defining the optimal cryoprotectant and concentration for cryopreservation of limbal stem cells2018
Dr Sanja Bojic
Dr Joseph Collin
Dr Min Yu
Professor Lyle Armstrong
Professor Francisco Figueiredo
et al.
Differences in the activity of endogenous BMP signalling impact on the ability of induced pluripotent stem cells to differentiate to corneal epithelial like cells2018
Dr Jane Carr-Wilkinson
Dr Nilendran Prathalingam
Dr Deepali Pal
Dr Mohammad Moad
Dr Peter James
et al.
Differentiation of human embryonic stem cells to sympathetic neurons: A model for understanding neuroblastoma pathogenesis.2018
Dr Adriana Buskin
Dr Lili Zhu
Dr Valeria Chichagova
Dr David Dolan
Dr Joseph Collin
et al.
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa2018
Dr iRINA Neganova
Lewis Cotts
Dr Andrew Banks
Katja Gassner
Professor Lyle Armstrong
et al.
EDG5 plays an important role in induction and maintenance of pluripotency2018
Professor Lyle Armstrong
Professor Majlinda Lako
Professor Miodrag Stojkovic
Ethical and safety issues of stem cell-based therapy2018
Majed Felemban
Dr Birthe Hilgen
Dr Nicola Hunt
Dr Dean Hallam
Dr Darin Zerti
et al.
Extracellular matrix components expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix2018
Minjin Jeong
Professor Majlinda Lako
Professor Lyle Armstrong
Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells2018
Heather Crawford
Professor Majlinda Lako
Dr Nicholas Hole
Professor Colin Jahoda
Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Haematopoiesis in Mouse Cultures2018
Dr Dean Hallam
Dr Birthe Hilgen
Dr Lili Zhu
Dr Min Yu
Dr Sanja Bojic
et al.
Human induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient dependent efficiency2018
Dr Dean Hallam
David Rawlings
David Steel
Professor Lyle Armstrong
Professor Majlinda Lako
et al.
In Reply to the Letter to the Editor from Hallam et al.: An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure2018
Dario Melguizo Sanchis
Dr Yaobo Xu
Dheraj Taheem
Dr Min Yu
Dr Katarzyna Tilgner
et al.
iPSC modelling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors2018
Dr Birthe Hilgen
Majed Felemban
Alex Sharpe
Dr Roman Bauer
Dr Dean Hallam
et al.
Laminin γ3 plays an important role in retinal lamination, photoreceptor organisation and ganglion cell differentiation2018
Dr Gustavo Figueiredo
Dr Oliver Baylis
Professor Majlinda Lako
Professor Francisco Figueiredo
Outcomes of penetrating keratoplasty following autologous cultivated limbal epithelial stem cell transplantation2018
Dr Oliver Russell
Pavandeep Rai
Dr Amy Reeve
Dr Karolina Rygiel
Professor Majlinda Lako
et al.
Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo2018
Dr Tomas Barta
Professor Majlinda Lako
Professor Lyle Armstrong
Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study2018
Professor Majlinda Lako
Special Series: Transplantation of Stem Cells into the Eye2018
Dr Dean Hallam
Dr Valeria Chichagova
Professor David Steel
Professor Majlinda Lako
The application of biomaterials to tissue engineering neural retina and retinal pigment epithelium2018
Dr Nicola Hunt
Dr Dean Hallam
Dr Carla Jackson
Dr Jinju Chen
Professor Majlinda Lako
et al.
3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development2017
Dr Irina Neganova
Dr Valeria Chichagova
Professor Lyle Armstrong
Professor Majlinda Lako
A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs2017
Dr Dean Hallam
Dr Joseph Collin
Dr Sanja Bojic
Dr Valeria Chichagova
Dr Adriana Buskin
et al.
An iPSC patient specific model of CFH (Y402H) polymorphism displays characteristic features of AMD and indicates a beneficial role for UV light exposure2017
Ellie Meader
Dr Tomas Barta
Dario Melguizo Sanchis
Dr Katarzyna Tilgner
Professor Lyle Armstrong
et al.
Brief Report: Pluripotent Stem Cell-Derived Hematopoietic Progenitors Are Unable to Downregulate Key Epithelial-Mesenchymal Transition-Associated miRNAs2017
Dr Gustavo Figueiredo
Dr Julian De Havilland
Professor Majlinda Lako
Professor Francisco Figueiredo
Cell Therapy in Practice2017
Dario Melguizo Sanchis
Dr Sujith Samarasinghe
Professor Lyle Armstrong
Professor Majlinda Lako
Concise review: Getting to the core of inherited bone marrow failures2017
Dr Laura Wadkin
Dr Irina Neganova
Dr Nick Parker
Dr Valeria Chichagova
Georgina Kay-Black
et al.
Dynamics of single human embryonic stem cells and their pairs: a quantitative analysis2017
Dr Gustavo Figueiredo
Dr Sanja Bojic
Professor Che Connon
Dr Ricardo Martins Gouveia
Professor Francisco Figueiredo
et al.
Gamma-irradiated human amniotic membrane decellularised with sodium dodecylsulfate is a more efficient substrate for the ex vivo expansion of limbal stem cells2017
Dr Roly Megaw
Dr Carla Mellough
Professor Majlinda Lako
Gelsolin dysregulation causes photoreceptor loss in induced pluripotent stem cell and animal models of retinitis pigmentosa2017
Professor Majlinda Lako
Hepatic differentiation of human iPSCs in different 3D models: A comparative study2017
Dr Laura Wadkin
Dr Sirio Orozco Fuentes
Dr Nick Parker
Professor Anvar Shukurov
Dr Irina Neganova
et al.
Human embryonic stem cell colony formation: statistical analysis and agent-based modelling2017
Dr Valeria Chichagova
Dr Dean Hallam
Dr Joseph Collin
Dr Adriana Buskin
Dr Gabriele Saretzki
et al.
Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A>G mitochondrial DNA mutation2017
Dr Chunbo Yang
Dr Yaobo Xu
Dr Min Yu
Dr David Lee
Dr John O'Sullivan
et al.
Induced pluripotent stem cell modelling of HLHS underlines the contribution of dysfunctional NOTCH signalling to impaired cardiogenesis2017
Professor Majlinda Lako
Professor Lyle Armstrong
Multiplex High-Throughput Targeted Proteomic Assay to Identify Induced Pluripotent Stem Cells2017
Professor Majlinda Lako
Professor Lyle Armstrong
Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience2017
Professor Majlinda Lako
Professor Miodrag Stojkovic
Stem Cell-Based Therapy in Transplantation and Immune-Mediated Diseases2017
Professor Lyle Armstrong
Professor Majlinda Lako
Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion2017
Dr Joseph Collin
Dr Lili Zhu
Professor Lyle Armstrong
Dr Irina Neganova
Professor Majlinda Lako
et al.
A Novel role for miR-1305 in Regulation of Pluripotency-Differentiation Balance, Cell Cycle and Apoptosis in Human Pluripotent Stem Cells2016
Professor Majlinda Lako
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Aging of Stem and Progenitor Cells: Mechanisms, Impact on Therapeutic Potential, and Rejuvenation2016
Dr Min Yu
Dr Sanja Bojic
Dr Gustavo Figueiredo
Dr Julian De Havilland
Professor Anne Dickinson
et al.
An important role for adenine, cholera toxin, hydrocortisone and triiodothyronine inthe proliferation, self-renewal and differentiation of limbal stem cells in vitro2016
Professor Majlinda Lako
Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency2016
Dr Carla Jackson
Professor Majlinda Lako
How to build a human2016
Dr Tomas Barta
Dr Joseph Collin
Dr Irina Neganova
Professor Lyle Armstrong
Professor Majlinda Lako
et al.
Inhibition of miR-145 Enhances Reprogramming of Human Dermal Fibroblasts to Induced Pluripotent Stem Cells2016
Professor Majlinda Lako
Insights into islet development and biology through characterization of a human iPSC-derived endocrine pancreas model2016
Dr Irina Neganova
Dr Evgeniya Shmeleva
Dr Jennifer Munkley
Dr Valeria Chichagova
Dr George Anyfantis
et al.
JNK/SAPK signalling is essential for efficient reprogramming of human fibroblasts to induced pluripotent stem cells2016
Professor Lyle Armstrong
Professor Majlinda Lako
Professor Miodrag Stojkovic
Primordial Germ Cells: Current Knowledge and Perspectives2016
Professor Majlinda Lako
Professor Miodrag Stojkovic
Stem Cells, Inflammation, and Fibrosis2016
Dr Lili Zhu
Dr Aurora Gomez Duran
Dr Gabriele Saretzki
Dr Katarzyna Tilgner
Dario Melguizo Sanchis
et al.
The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages2016
Dr Nicola Hunt
Professor Majlinda Lako
Tissue engineering using pluripotent stem cells: multidisciplinary approaches to accelerate bench-to-bedside transition2016
Dr Gustavo Figueiredo
Dr Jeffry Hogg
Arthur Okonkwo
Dr Deborah Stocken
Professor Simi Ali
et al.
Understanding ocular surface inflammation in tears before and after ex vivo expanded autologous limbal stem cell transplantation2016
Dr Joseph Collin
Dr Carla Jackson
Dr Birthe Hilgen
Professor Majlinda Lako
Using Zinc Finger Nuclease Technology to Generate CRX-Reporter Human Embryonic Stem Cells as a Tool to Identify and Study the Emergence of Photoreceptors Precursors During Pluripotent Stem Cell Differentiation2016
Dr Chunbo Yang
Professor Majlinda Lako
Professor Lyle Armstrong
Concise Review: Cardiac Disease Modeling Using Induced Pluripotent Stem Cells2015
Dr Valeria Chichagova
Dr Irene Sanchez-Vera
Professor Lyle Armstrong
Professor David Steel
Professor Majlinda Lako
et al.
Generation of Human Induced Pluripotent Stem Cells Using RNA-Based Sendai Virus System and Pluripotency Validation of the Resulting Cell Population2015
Dr Carla Jackson
Joseph Collin
Mahmoud Khazim
Dr Kathryn White
Professor Evelyne Sernagor
et al.
IGF-1 Signaling Plays an Important Role in the Formation of Three-Dimensional Laminated Neural Retina and Other Ocular Structures From Human Embryonic Stem Cells2015
Majed Felemban
Dr Nicola Hunt
Dr Birthe Hilgen
Dr Carla Mellough
Professor Majlinda Lako
et al.
Investigation of extracellular matrix (ECM) component expression in developing retina2015
Professor Francisco Figueiredo
Professor Majlinda Lako
Dr Oliver Baylis
Dr Gustavo Figueiredo
Patient reported outcomes before and following ex vivo cultured autologous limbal stem cell transplantation for total unilateral limbal stem cell deficiency2015
Dr Roly Megaw
Dr Carla Mellough
Professor Majlinda Lako
Use of induced pluripotent stem-cell technology to understand photoreceptor cytoskeletal dynamics in retinitis pigmentosa2015
Professor Majlinda Lako
Dr Joseph Collin
Dr Carla Jackson
Dr Birthe Hilgen
Using zinc finger nuclease technology to generate reporter-labelled human pluripotent stem cells as a tool to optimize photoreceptor transplantation2015
Dr Saba Habibollah
Dr Katarzyna Tilgner
Dr Joseph Collin
Dr Tomas Barta
Raf Hussain
et al.
An Induced Pluripotent Stem Cell Model of Hypoplastic Left Heart Syndrome (HLHS) Reveals Multiple Expression and Functional Differences in HLHS-Derived Cardiac Myocytes2014
Dr Irina Neganova
Dr Katarzyna Tilgner
Dr Adriana Buskin
Iliana Paraskevopoulou
Dr Stuart Atkinson
et al.
CDK1 plays an important role in the maintenance of pluripotency and genomic stability in human pluripotent stem cells2014
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Professor Majlinda Lako
Concise Review: The Epigenetic Contribution to Stem Cell Ageing: Can We Rejuvenate Our Older Cells?2014
Professor Majlinda Lako
Professor Lyle Armstrong
Engraftment's Holy Grail: is one signal enough?2014
Dr Carla Jackson
Dr Joseph Collin
Professor Evelyne Sernagor
Nicholas Wride
Professor David Steel
et al.
Lab generated retina: Realizing the dream2014
Professor Majlinda Lako
Professor Miodrag Stojkovic
Stem Cells as New Agents for the Treatment of Infertility: Current and Future Perspectives and Challenges2014
Sai Kolli
Dr Sajjad Ahmad
Professor Majlinda Lako
Professor Francisco Figueiredo
Successful Application of Ex Vivo Expanded Human Autologous Oral Mucosal Epithelium for the Treatment of Total Bilateral Limbal Stem Cell Deficiency2014
Dr Katarzyna Tilgner
Dr Irina Neganova
Sun Yung
Chatcha Singhapol
Dr Gabriele Saretzki
et al.
A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors2013
Dr Mohammad Moad
Dr Deepali Pal
Dr Anastasia Hepburn
Dr Stuart Williamson
Laura Wilson
et al.
A novel model of urinary tract differentiation, tissue regeneration, and disease: Reprogramming human prostate and bladder cells into induced pluripotent stem cells2013
Dr Oliver Baylis
Professor Francisco Figueiredo
Professor Majlinda Lako
Dr Sajjad Ahmad
An investigation of donor and culture parameters which influence epithelial outgrowths from cultured human cadaveric limbal explants2013
Dr Katarzyna Tilgner
Dr Irina Neganova
Chatcha Singhapol
Dr Gabriele Saretzki
Jerome Evans
et al.
Brief Report: A Human Induced Pluripotent Stem Cell Model of Cernunnos Deficiency Reveals an Important Role for XLF in the Survival of the Primitive Hematopoietic Progenitors2013
Sun Yung
Dr Katarzyna Tilgner
Dr Maria Ledran
Dr Saba Habibollah
Dr Irina Neganova
et al.
Brief Report: Human Pluripotent Stem Cell Models of Fanconi Anemia Deficiency Reveal an Important Role for Fanconi Anemia Proteins in Cellular Reprogramming and Survival of Hematopoietic Progenitors2013
Dr Mohammad Moad
Dr Anastasia Hepburn
Professor Majlinda Lako
Dr Deepali Pal
Professor Rakesh Heer
et al.
Generation of induced pluripotent stem cells from human urinary tract cells2013
Dr Aaron Ions Gardner
Dr Andrew Owens
Professor Majlinda Lako
Human hair follicle dermal cells provide enhanced support for both epithelial and embryonic stem cell culture proliferation and maintenance2013
Professor Majlinda Lako
Professor Miodrag Stojkovic
Mesenchymal Stem Cells for Diabetes and Related Complications2013
Dr Alison Dickinson
Professor Majlinda Lako
Sai Kolli
Professor Francisco Figueiredo
Outcomes of ex vivo expanded limbal stem cell transplantation in humans2013
Dr Stuart Atkinson
Professor Majlinda Lako
Professor Lyle Armstrong
Potential for Pharmacological Manipulation of Human Embryonic Stem Cells2013
Dr Charlie Osei-Bempong
Professor Francisco Figueiredo
Professor Majlinda Lako
The limbal epithelium of the eye A review of limbal stem cell biology, disease and treatment2013
Stuart Atkinson
Dr Joseph Collin
Dr George Anyfantis
Professor Majlinda Lako
Professor Lyle Armstrong
et al.
A Putative Role for the Immunoproteasome in the Maintenance of Pluripotency in Human Embryonic Stem Cells2012
Dr Yan Jiang
Dr Katarzyna Tilgner
Dr Gabriele Saretzki
Professor Majlinda Lako
Professor Lyle Armstrong
et al.
Derivation and functional analysis of patient specific induced pluripotent stem cells (IPSCS) as an in vitro model of chronic granulomatous disease2012
Dr Yan Jiang
Dr Katarzyna Tilgner
Dr Gabriele Saretzki
Professor Majlinda Lako
Professor Lyle Armstrong
et al.
Derivation and Functional Analysis of Patient Specific Induced Pluripotent Stem Cells as an In Vitro Model of Chronic Granulomatous Disease2012
Dr Yan Jiang
Dr Katarzyna Tilgner
Dr Gabriele Saretzki
Professor Majlinda Lako
Professor Lyle Armstrong
et al.
Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease2012
Dr Carla Jackson
Professor Evelyne Sernagor
Professor David Steel
Professor Majlinda Lako
Efficient Stage-Specific Differentiation of Human Pluripotent Stem Cells Toward Retinal Photoreceptor Cells2012
Dr John Blackwood
Dr Laura Greaves
Laura Wilson
Rob Pickard
Professor Majlinda Lako
et al.
Lineage tracking in situ: Where are the prostate stem cells? What are they doing?2012
Professor Lyle Armstrong
Professor Majlinda Lako
Professor Miodrag Stojkovic
Our Top 10 Developments in Stem Cell Biology over the Last 30 Years2012
Professor Majlinda Lako
SCL/TAL1 Regulates Hematopoietic Specification From Human Embryonic Stem Cells2012
Professor Majlinda Lako
Using human pluripotent stem cells to understand our beginnings and treat disease2012
Dr Oliver Baylis
Professor Francisco Figueiredo
Dr Christin Henein
Professor Majlinda Lako
Dr Sajjad Ahmad
et al.
13 Years of Cultured Limbal Epithelial Cell Therapy: A Review of the Outcomes2011
Dr Irina Neganova
Dr Stuart Atkinson
Dr Joao Passos
Professor Thomas von Zglinicki
Professor Lyle Armstrong
et al.
An Important Role for CDK2 in G1 to S Checkpoint Activation and DNA Damage Response in Human Embryonic Stem Cells2011
Dr Joseph Collin
Professor Majlinda Lako
Concise Review: Putting a Finger on Stem Cell Biology: Zinc Finger Nuclease-Driven Targeted Genetic Editing in Human Pluripotent Stem Cells2011
Sun Yung
Dr Maria Ledran
Ian Dimmick
Dr Nicholas Slater
Iliana Paraskevopoulou
et al.
Large-scale transcriptional profiling and functional assays reveal important roles for Rho-GTPase signalling and SCL during haematopoietic differentiation of human embryonic stem cells2011
Professor Majlinda Lako
Law, Ethics, Religion, and Clinical Translation in the 21st Century - A Conversation with Anthony D. Ho2011
Professor Majlinda Lako
Law, Ethics, Religion, and Clinical Translation in the 21st Century-A Conversation with Cinzia Rota2011
Professor Miodrag Stojkovic
Professor Majlinda Lako
Neural Stem Cells, a Step Closer to Clinic?2011
Dr George Anyfantis
Professor Lyle Armstrong
Professor Majlinda Lako
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage2011
Dr Katarzyna Tilgner
Dr Stuart Atkinson
Sun Yung
Anna Golebiewska
Professor Miodrag Stojkovic
et al.
Expression of GFP Under the Control of the RNA Helicase VASA Permits Fluorescence-Activated Cell Sorting Isolation of Human Primordial Germ Cells2010
Dr Maria Ledran
Professor Majlinda Lako
Hematopoietic differentiation from human ESCs as a model for developmental studies and future clinical translations. Invited review following the FEBS Anniversary Prize received on 5 July 2009 at the 34th FEBS Congress in Prague2010
Professor Lyle Armstrong
Dr Katarzyna Tilgner
Dr Gabriele Saretzki
Dr Stuart Atkinson
Professor Miodrag Stojkovic
et al.
Human Induced Pluripotent Stem Cell Lines Show Stress Defense Mechanisms and Mitochondrial Regulation Similar to Those of Human Embryonic Stem Cells2010
Dr Katarzyna Tilgner
Dr Chunbo Yang
Dr Irina Neganova
Professor Lyle Armstrong
Professor Majlinda Lako
et al.
Human-Induced Pluripotent Stem Cell-Derived Models for the Study of Spinal Muscular Atrophy2010
Professor Majlinda Lako
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Induced Pluripotent Stem Cells : It Looks Simple but Can Looks Deceive?2010
Professor Majlinda Lako
Law, Ethics, Religion, and Clinical Translation in the 21(st) Century - A Discussion with Pete Coffey2010
Professor Majlinda Lako
Law, Ethics, Religion, and Clinical Translation in the 21st Century - A Discussion with Stephen Bellamy2010
Professor Majlinda Lako
Law, Ethics, Religion, and Clinical Translation in the 21st Century-A Conversation with Il-Hoan Oh2010
Professor Majlinda Lako
Law, Ethics, Religion, and Clinical Translation in the 21st Century-A Discussion with Andrew Webster2010
Professor Majlinda Lako
Law, Ethics, Religion, and Clinical Translation in the 21st Century-A Discussion with Derek Hei2010
Professor Majlinda Lako
Law, Ethics, Religion, and Clinical Translation in the 21st Century-A Discussion with John Sinden2010
Dr Stuart Atkinson
Professor Lyle Armstrong
Professor Derek Mann
Professor Majlinda Lako
Opposing Putative Roles for Canonical and Noncanonical NF kappa B Signaling on the Survival, Proliferation, and Differentiation Potential of Human Embryonic Stem Cells2010
Dr Katarzyna Tilgner
Professor Lyle Armstrong
Professor Majlinda Lako
Positive effect of human ESC conditioned medium on somatic cell reprogramming2010
Professor Todd Marder
Professor Majlinda Lako
Retinoid supplementation of differentiating human neural progenitors and embryonic stem cells leads to enhanced neurogenesis in vitro2010
Sai Kolli
Dr Sajjad Ahmad
Professor Majlinda Lako
Professor Francisco Figueiredo
Successful Clinical Implementation of Corneal Epithelial Stem Cell Therapy for Treatment of Unilateral Limbal Stem Cell Deficiency2010
Dr Aiqing Chen
Bernard Siow
Professor Andrew Blamire
Professor Majlinda Lako
Dr Gavin Clowry
et al.
Transplantation of magnetically labeled mesenchymal stem cells in a model of perinatal brain injury2010
Dr Meenakshi Choudhary
Professor Majlinda Lako
Professor Miodrag Stojkovic
Professor Alison Murdoch
"Beauty and Beast'' molecule; HA in early human development2009
Dr Meenakshi Choudhary
Professor Majlinda Lako
Professor Miodrag Stojkovic
Professor Alison Murdoch
"Beauty and Beast" molecule: HA in early human development2009
Dr Irina Neganova
Dr Stuart Atkinson
Dr George Anyfantis
Dr Owen Hughes
Professor Tom Strachan
et al.
A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A2009
Professor Majlinda Lako
Balancing Work and Life: A Conversation with Barbara Knowles2009
Professor Majlinda Lako
Balancing Work and Life: A Conversation with Fiona Watt2009
Professor Majlinda Lako
Balancing Work and Life: A Conversation with George Daley2009
Professor Majlinda Lako
Balancing Work and Life: A Conversation with Konrad Hochedlinger2009
Professor Majlinda Lako
Balancing Work and Life: A Conversation with Lesley Forrester2009
Professor Majlinda Lako
Balancing Work and Life: A Conversation with Marella de Bruijn2009
Professor Majlinda Lako
Balancing Work and Life: A Conversation with Margaret "Peggy" Goodell2009
Professor Majlinda Lako
Balancing Work and Life: A Conversation with Mina Bissell2009
Professor Majlinda Lako
Balancing Work and Life: A Conversation with Sean Morrison2009
Professor Majlinda Lako
Balancing Work and Life: An Interview with Connie Eaves2009
Professor Majlinda Lako
Balancing Work and Life: An Interview with Kathleen Sakamoto2009
Professor Majlinda Lako
Balancing Work and Life: Finding Our Inspirations2009
Professor Majlinda Lako
Consensus Guidance for Banking and Supply of Human Embryonic Stem Cell Lines for Research Purposes2009
Anna Golebiewska
Stuart Atkinson
Professor Majlinda Lako
Professor Lyle Armstrong
Epigenetic Landscaping During hESC Differentiation to Neural Cells2009
Dr Irina Neganova
Stuart Atkinson
Professor Majlinda Lako
Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells2009
Professor Majlinda Lako
Dr Irina Neganova
Professor Lyle Armstrong
G(1) to S transition and pluripotency Two sides of the same coin?2009
Dr Carla Jackson
Professor David Steel
Professor Majlinda Lako
Genetic basis of inherited macular dystrophies and implications for stem cell therapy2009
Dr Chunbo Yang
Dr Rebecca Stewart
Dr George Anyfantis
Stuart Atkinson
Dr Gabriele Saretzki
et al.
A key role for telomerase reverse transcriptase unit in modulating human embryonic stem cell proliferation, cell cycle dynamics, and in vitro differentiation2008
Dr Sajjad Ahmad
Sai Kolli
Ian Dimmick
Professor Lyle Armstrong
Professor Francisco Figueiredo
et al.
A putative role for RHAMM/HMMR as a negative marker of stem cell-containing population of human limbal epithelial cells2008
Professor Toivo Maimets
Dr Irina Neganova
Professor Lyle Armstrong
Professor Majlinda Lako
Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells2008
Dr Gabriele Saretzki
Theresia Walter
Dr Joao Passos
Dr Rebecca Stewart
Dr Simon Hoare
et al.
Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells2008
Dr Maria Ledran
Professor Lyle Armstrong
Ian Dimmick
Dr Rebecca Lang
Sun Yung
et al.
Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches2008
Stuart Atkinson
Dr Rebecca Stewart
Professor Majlinda Lako
Professor Lyle Armstrong
Epigenetic marking prepares the human HOXA cluster for activation during differentiation of pluripotent cells2008
Dr Irina Neganova
Professor Majlinda Lako
G1 to S phase cell cycle transition in somatic and embryonic stem cells2008
Dr Katarzyna Tilgner
Stuart Atkinson
Anna Golebiewska
Professor Miodrag Stojkovic
Professor Majlinda Lako
et al.
Isolation of Primordial Germ Cells from Differentiating Human Embryonic Stem Cells2008
Sai Kolli
Professor Majlinda Lako
Professor Francisco Figueiredo
Dr Sajjad Ahmad
Loss of corneal epithelial stem cell properties in outgrowths from human limbal explants cultured on intact amniotic membrane2008
Petra Stojkovic
Professor Lyle Armstrong
Professor Majlinda Lako
Professor Miodrag Stojkovic
Non-invasive Imaging of Stem Cells by Scanning Ion Conductance Microscopy: Future Perspective2008
Dr Rebecca Stewart
Dr Chunbo Yang
Dr George Anyfantis
Dr Nicholas Hole
Professor Tom Strachan
et al.
Silencing of the expression of pluripotent driven-reporter genes stably transfected into human pluripotent cells2008
Dr Hannah Gautrey
Professor Majlinda Lako
Dr Judith Hall
Professor John Hesketh
Staufen1 is expressed in preimplantation mouse embryos and is required for embryonic stem cell differentiation2008
Dr Irina Neganova
Professor Majlinda Lako
Cell cycle regulation in human embryonic stem cells2007
Professor Majlinda Lako
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative2007
Dr Sajjad Ahmad
Dr Rebecca Stewart
Sun Yung
Sai Kolli
Professor Lyle Armstrong
et al.
Differentiation of human embryonic stem cells into corneal epithelial-like cells by in vitro replication of the corneal epithelial stem cell niche2007
Dr Meenakshi Choudhary
Petra Stojkovic
Dr Louise Hyslop
Dr George Anyfantis
Professor Mary Herbert
et al.
Putative role of hyaluronan and its related genes, HAS2 and RHAMM, in human early preimplantation embryogenesis and embryonic stem cell characterization2007
Dr Sajjad Ahmad
Professor Francisco Figueiredo
Professor Majlinda Lako
Corneal epithelial stem cells: characterization, culture and transplantation2006
Petra Stojkovic
Professor Lyle Armstrong
Professor Majlinda Lako
Professor Miodrag Stojkovic
Derivation of human embryonic stem cells from developing and arrested embryos2006
Professor Lyle Armstrong
Professor Majlinda Lako
Professor Miodrag Stojkovic
Epigenetic modification is central to genome reprogramming in somatic cell nuclear transfer2006
Dr Graham Holliman
Dr Ali Aldibbiat
Dr Susan Campbell
Professor Derek Manas
Professor Majlinda Lako
et al.
Expression of the pluripotent stem cell marker OCT-4 in normal adult human pancreas2006
Dr Rebecca Stewart
Professor Miodrag Stojkovic
Professor Majlinda Lako
Mechanisms of self-renewal in human embryonic stem cells2006
Professor Lyle Armstrong
Professor Majlinda Lako
The future of human nuclear transfer?2006
Professor Lyle Armstrong
Dr Owen Hughes
Sun Yung
Dr Louise Hyslop
Dr Rebecca Stewart
et al.
The role of PI3K/AKT, MAPK/ERK and NFκβ signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis2006
Petra Stojkovic
Professor Majlinda Lako
Dr Rebecca Stewart
Professor Lyle Armstrong
Jerome Evans
et al.
An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells2005
Petra Stojkovic
Professor Majlinda Lako
Dr Rebecca Stewart
Professor Lyle Armstrong
Professor Mary Herbert
et al.
An Autogeneic Feeder Cell System That Efficiently Supports Growth of Undifferentiated Human Embryonic Stem Cells2005
Professor Miodrag Stojkovic
Petra Stojkovic
Vanessa Hall
Professor Lyle Armstrong
Professor Mary Herbert
et al.
Derivation of a human blastocyst after heterologous nuclear transfer to donated oocytes2005
Dr Louise Hyslop
Professor Miodrag Stojkovic
Professor Lyle Armstrong
Theresia Walter
Petra Stojkovic
et al.
Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages2005
Petra Stojkovic
Professor Majlinda Lako
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Human embryonic stem cells express markers of pluripotency and differentiate under long-term in vitro growth conditions2005
Dr Louise Hyslop
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Professor Majlinda Lako
Human embryonic stem cells: Biology and clinical implications2005
Petra Stojkovic
Professor Majlinda Lako
Professor Lyle Armstrong
Jerome Evans
Professor Miodrag Stojkovic
et al.
Human-serum matrix supports undifferentiated growth of human embryonic stem cells2005
Professor Majlinda Lako
Professor Miodrag Stojkovic
In search of the best candidate for regeneration of ischemic tissues: are embryonic/fetal stem cells more advantageous than adult counterparts?2005
Professor Majlinda Lako
Professor Miodrag Stojkovic
In search of the best candidate for regeneration of ischemic tissues: Are embryonic/fetal stem cells more advantageous than adult counterparts?2005
Dr Rebecca Stewart
Professor Majlinda Lako
Neural development by transplanted human embryonal carcinoma stem cells expressing green fluorescent protein2005
Professor Lyle Armstrong
Dr Gabriele Saretzki
Dr Heiko Peters
Ilka Wappler
Dr Nicholas Hole
et al.
Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage2005
Dr Rebecca Stewart
Professor Miodrag Stojkovic
Professor Majlinda Lako
Signalling pathways in human ES cells2005
Dr Sajjad Ahmad
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Ian Dimmick
Dr Louise Hyslop
et al.
The identification and characterisation of human corneal epithelial progenitors on the basis of high aldehyde dehydrogenase activity2005
Professor Lyle Armstrong
Professor Majlinda Lako
Dr Nicholas Hole
A role for nucleoprotein Zap3 in the reduction of telomerase activity during embryonic stem cell differentiation2004
Professor Lyle Armstrong
Professor Majlinda Lako
Dr Gabriele Saretzki
Dr Nicholas Hole
A role for nucleoprotein Zap3 in the reduction of telomerase activity during embryonic stem cell differentiation2004
Professor Miodrag Stojkovic
Professor Majlinda Lako
Petra Stojkovic
Dr Rebecca Stewart
Professor Lyle Armstrong
et al.
Derivation of human embryonic stem cells from day-8 blastocysts recovered after three-step in vitro culture2004
Professor Miodrag Stojkovic
Professor Majlinda Lako
Professor Tom Strachan
Professor Alison Murdoch
Derivation, growth and applications of human embryonic stem cells2004
Dr Sajjad Ahmad
Dr Louise Hyslop
Professor Colin Jahoda
Professor Tom Strachan
Professor Majlinda Lako
et al.
From embryo to eye - Human embryonic stem cell markers OCT-4 and NANOG are localised to adult limbal epithelium2004
Dr Rebecca Stewart
Professor Majlinda Lako
Human embryonal carcinoma stem cells expressing green fluorescent protein form functioning neurons in vitro: A research tool for co-culture studies2004
Dr Susan Campbell
Professor Majlinda Lako
PDCD4 is a novel gene that is upreglated during pancreatic islet neogenesis, GLP-1 stimulation of whole islets and differentiation of embryonic stem cells to a beta cell phenotype2004
Professor Lyle Armstrong
Professor Miodrag Stojkovic
Ian Dimmick
Dr Sajjad Ahmad
Petra Stojkovic
et al.
Phenotypic characterization of murine primitive hematopoietic progenitor cells isolated on basis of aldehyde dehydrogenase activity2004
Dr Susan Campbell
Professor Lyle Armstrong
Dr Nicholas Hole
Professor Majlinda Lako
Programmed cell death gene 4 (PDCD4): A novel gene upregulated during islet neogenesis and embryonic stem cell differentiation2004
Dr Gabriele Saretzki
Professor Lyle Armstrong
Alan Leake
Professor Majlinda Lako
Professor Thomas von Zglinicki
et al.
Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells2004
Professor Majlinda Lako
Professor Lyle Armstrong
Paul Cairns
Dr Simon Harris
Dr Nicholas Hole
et al.
Hair follicle dermal cells repopulate the mouse haematopoietic system2002
Professor Majlinda Lako
Emerita Professor Susan Lindsay
Paul Cairns
Professor Lyle Armstrong
Dr Nicholas Hole
et al.
Characterisation of Wnt gene expression during the differentiation of murine embryonic stem cells in vitro: Role of Wnt3 in enhancing haematopoietic differentiation2001
Professor Lyle Armstrong
Professor Majlinda Lako
Paul Cairns
mTert expression correlates with telomerase activity during the differentiation of murine embryonic stem cells2000
Professor Majlinda Lako
Dr Nicholas Hole
Searching the unknown with gene trapping2000
Professor Majlinda Lako
Professor Tom Strachan
Mutation screening in British 21-hydroxylase deficiency families and development of novel microsatellite based approaches to prenatal diagnosis1999