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International workshop: islet transplantation without borders enabling islet transplantation in Greece with international collaboration and innovative technology

Lookup NU author(s): Professor James Shaw


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Recently, initiatives have been undertaken to establish an islet transplantation program in Athens, Greece. A major hurdle is the high cost associated with the establishment and maintenance of a clinical-grade islet manufacturing center. A collaboration was established with the University Hospitals of Geneva, Switzerland, to enable remote islet cell manufacturing with an established and validated fully operational team. However, remote islet manufacturing requires shipment of the pancreas from the procurement to the islet manufacturing site (in this case from anywhere in Greece to Geneva) and then shipment of the islets from the manufacturing site to the transplant site (from Geneva to Athens). To address challenges related to cold ischemia time of the pancreas and shipment time of islets, a collaboration was initiated with the University of Arizona, Tucson, USA. An international workshop was held in Athens, December 2011, to mark the start of this collaborative project. Experts in the field presented in three main sessions: (i) islet transplantation: state-of-the-art and the network approach; (ii) technical aspects of clinical islet transplantation and outcomes; and (iii) islet manufacturing from the donated pancreas to the islet product. This manuscript presents a summary of the workshop.

Publication metadata

Author(s): Papas KK, Karatzas T, Berney T, Minor T, Pappas P, Pattou F, Shaw J, Toso C, Schuurman HJ

Publication type: Article

Publication status: Published

Journal: Clinical Transplantation

Year: 2013

Volume: 27

Issue: 2

Pages: E116-E125

Print publication date: 01/03/2013

Online publication date: 18/01/2013

Acceptance date: 02/11/2012

ISSN (print): 0902-0063

ISSN (electronic): 1399-0012

Publisher: Wiley-Blackwell Publishing, Inc.


DOI: 10.1111/ctr.12066


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Funder referenceFunder name
Diabetes UK
Giner, Inc.
Instech Laboratories, Inc.
Diabetes Research and Wellness Foundation
Wilson Wolf Manufacturing Corporation
R43DK06965NIH/NIDDK SBIR grants
R44DK069865NIH/NIDDK SBIR grants
R43DK070400NIH/NIDDK SBIR grants
R44DK070400NIH/NIDDK SBIR grants