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Skin manifestations of mitochondrial dysfunction: more important than previously thought

Lookup NU author(s): Dr SarahJayne Boulton, Dr Amy Bowman, Roxanna Koohgoli, Professor Mark Birch-Machin

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).


Abstract

Mitochondrial DNA (mtDNA) research is emerging within the dermatological field as a unique biomarker for diagnostic, prognostic and even therapeutic exploration. Since the first review of the role of mtDNA in skin disease was authored by our group some 14 years ago (1), there have been many exciting observations linking mitochondria to the defective structural, cell signaling, and oxidative damage pathways that promote skin disease manifestation


Publication metadata

Author(s): Boulton SJ, Bowman A, Koohgoli R, Birch-Machin MA

Publication type: Article

Publication status: Published

Journal: Experimental Dermatology

Year: 2015

Volume: 24

Issue: 1

Pages: 12-13

Print publication date: 01/01/2015

Online publication date: 09/01/2015

Acceptance date: 11/12/2014

Date deposited: 20/05/2015

ISSN (print): 0906-6705

ISSN (electronic): 1600-0625

Publisher: Wiley-Blackwell Publishing Ltd.

URL: http://dx.doi.org/10.1111/exd.12597

DOI: 10.1111/exd.12597


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