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Browsing publications by Professor Mark Birch-Machin.

Newcastle AuthorsTitleYearFull text
Jessica Moor
Professor Mark Birch-Machin
Bioenergy and stressed out skin; what can we do?2022
Professor Mark Birch-Machin
Targeting mitochondria in dermatological therapy: beyond oxidative damage and skin aging2022
Wil Reynolds
Dr Amy Bowman
Dr Peter Hanson
Professor Mark Birch-Machin
Adaptive responses to air pollution in human dermal fibroblasts and their potential roles in ageing2021
Dr Eyman Rashdan
Dr Khimara Naidoo
Professor Mark Birch-Machin
Distinctive clinical and histological characteristics of atrophic and hypertrophic facial photoageing2021
Becky Zhu
Dr Sophie Cassidy
Dr Hugo Hiden
Professor Mike Trenell
Professor Mike Catt
et al.
Exploration of sleep as a specific risk factor for poor metabolic and mental health: a UK Biobank study of 84,404 participants2021
Rach Dixon
Dr Wing Man Lau
Dr Philip Manning
Professor Mark Birch-Machin
Professor Moein Moghimi
et al.
Microneedle-based devices for point-of-care infectious disease diagnostics2021
Dr Amy Bowman
Professor Mark Birch-Machin
Mitochondrial DNA as a sensitive biomarker of UV-Induced Cellular Damage in Human Skin2021
Professor Mark Birch-Machin
The Inhibition of Metabolic Inflammation by EPA is Associated with Enhanced Mitochondrial Fusion and Insulin Signalling in Human Primary Myotubes2021
Wil Reynolds
Dr Peter Hanson
Professor Mark Birch-Machin
Exposing human primary dermal fibroblasts to particulate matter induces changes associated with skin aging2020
Laura Hudson
Dr Eyman Rashdan
Catherine Bonn
David Rawlings
Professor Mark Birch-Machin
et al.
Individual and combined effects of the infrared, visible and ultraviolet light components of solar radiation on damage biomarkers in human skin cells2020
Dr Amy Bowman
Dr Glyn Nelson
Professor Mark Birch-Machin
Metabolic dysfunction in human skin: Restoration of mitochondrial integrity and metabolic output by nicotinamide (niacinamide) in primary dermal fibroblasts from older aged donors2020
Roisin Stout
Professor Mark Birch-Machin
Mitochondria's role in skin ageing2019
Becky Zhu
Professor Mike Catt
Dr Sophie Cassidy
Professor Mark Birch-Machin
Professor Mike Trenell
et al.
Objective sleep assessment in >80,000 UK mid-life adults: associations with sociodemographic characteristics, physical activity and caffeine2019
Rebecca Hanna
David Moore
Professor Mark Birch-Machin
Optimised detection of mitochondrial DNA strand breaks2019
Professor Mark Birch-Machin
The Mitochondria and Complex II- Linchpin for skin ageing and photoaging2019
Dr Tom Clifford
Dr Amy Bowman
Tess Capper
Dr Dean Allerton
Dr Emma Foster
et al.
A pilot study investigating reactive oxygen species production in capillary blood after a marathon and the influence of an antioxidant-rich beetroot juice.2018
Nik Zakaria
Dr Edward Okello
Professor Mark Birch-Machin
Dr Amy Bowman
In vitro protective effects of an aqueous extract of Clitoria ternatea L. flower against hydrogen peroxide-induced cytotoxicity and UV-induced mtDNA damage in human keratinocytes2018
Dr Amy Bowman
Professor Mark Birch-Machin
Nicotinamide enhances mitochondrial function in human skin cells2018
Catherine Bonn
Dr Khimara Naidoo
Professor Mark Birch-Machin
Sunlight,diet and pollution- effects on oxidative stress and skin ageing2018
Professor Mark Birch-Machin
Dr Ellen Hatch
Tiron is Protective Against ROS-Induced Damage in Human Bronchial Epithelial Cells2018
Professor Mark Birch-Machin
UVA-induced Carbon-Centered Radicals in Lightly Pigmented Cells detected using ESR Spectroscopy2018
Dr Khimara Naidoo
Rebecca Hanna
Professor Mark Birch-Machin
What is the role of mitochondrial dysfunction in skin photoaging?2018
Dr Angela Rodrigues
Professor Falko Sniehotta
Professor Mark Birch-Machin
Professor Vera Araujo-Soares
Aware, motivated and striving for a ‘safe tan’: an exploratory mixed-method study of sun-protection during holidays2017
Laura Hudson
Dr Khimara Naidoo
Dr Simon Wilkinson
Professor Mark Birch-Machin
Bad air gets under your skin2017
Dr Khimara Naidoo
Professor Mark Birch-Machin
Oxidative Stress and Ageing: The Influence of Environmental Pollution, Sunlight and Diet on Skin2017
Dr Angela Rodrigues
Professor Falko Sniehotta
Professor Mark Birch-Machin
Professor Vera Araujo-Soares
Systematic and iterative development of a smartphone application to promote sun-protection amongst holidaymaker2017
Dr Amy Bowman
Professor Mark Birch-Machin
Age-dependent decrease of mitochondrial complex II activity in human skin fibroblasts2016
Dr Amy Bowman
Professor Mark Birch-Machin
Cosmetic sunscreen formulations provide protection against UVR-induced mitochondrial DNA damage in human skin cells2016
Laura Hudson
Dr Amy Bowman
Dr Eyman Rashdan
Professor Mark Birch-Machin
Mitochondrial damage and ageing using skin as a model organ2016
Professor Mark Birch-Machin
Dr Amy Bowman
Oxidative stress and ageing2016
Dr Jennifer Latimer
Dr James Lloyd
Emeritus Professor Brian Diffey
Professor Mark Birch-Machin
Determination of the action spectrum of UVR-induced mitochondrial DNA damage in human skin cells2015
Dr SarahJayne Boulton
Professor Mark Birch-Machin
Impact of hyperpigmentation on superoxide flux and melanoma cell metabolism at mitochondrial complex II.2015
Dr Amy Bowman
Professor Mark Birch-Machin
Mitochondrial DNA as a Biosensor of UV Exposure in Human Skin.2015
Dr Anne Oyewole
Professor Mark Birch-Machin
Mitochondrial-targeted antioxidants2015
Dr Amy Bowman
Professor Mark Birch-Machin
Oxidative stress - a key emerging impact factor in health, ageing, lifestyle and aesthetics2015
Dr Anne Oyewole
Professor Mark Birch-Machin
Sebum, Inflammasomes and the Skin: current concepts and future perspective2015
Dr SarahJayne Boulton
Dr Amy Bowman
Roxanna Koohgoli
Professor Mark Birch-Machin
Skin manifestations of mitochondrial dysfunction: more important than previously thought2015
Dr Amy Bowman
Professor Mark Birch-Machin
Professor Georg Lietz
The Effect Of Nutritional Intervention On Blood Oxidative Stress Levels2015
Dr SarahJayne Boulton
Professor Mark Birch-Machin
The impact of hyperpigmentation on mitochondria: a comparative approach to investigating bioenergetic pathways in melanoma and keratinocyte cell types2015
Alasdair Anderson
Dr Amy Bowman
Dr SarahJayne Boulton
Dr Philip Manning
Professor Mark Birch-Machin
et al.
A role for human mitochondrial complex II in the production of reactive oxygen species in human skin2014
Dr Angela Rodrigues
Professor Falko Sniehotta
Professor Mark Birch-Machin
Professor Vera Araujo-Soares
Acceptability and feasibility of a mobile-phone intervention to promote sun safe behaviors amongst holidaymakers: findings from the internal pilot of the miskin randomized trial2014
Dr Amy Bowman
Dr Philip Manning
Professor Mark Birch-Machin
Applicability of dermoscopy for evaluation of patients' response to nonablative therapies for the treatment of superficial basal cell carcinoma2014
Dr Anne Oyewole
Professor Mark Birch-Machin
Comparing the effects of mitochondrial targeted and localized antioxidants with cellular antioxidants in human skin cells exposed to UVA and hydrogen peroxide 2014
Professor Mark Birch-Machin
Effects of polyphenols on mitochondrial DNA damage in skin fibroblasts2014
Dr SarahJayne Boulton
Professor Mark Birch-Machin
Melanin reduces acute mitochondrial superoxide generation: a real-time amperometric study2014
Dr Amy Bowman
Professor Mark Birch-Machin
Responses to acute sun exposure in large whales2014
Dr Amy Bowman
Professor Mark Birch-Machin
Dr SarahJayne Boulton
The roles of the mitochondrial respiratory chain complexes in UVA-induced oxidative stress in human skin cells compared to other cell types2014
Dr Jennifer Latimer
Professor Mark Birch-Machin
Using the Seahorse XF Analyser to evaluate real-time cellular respiration of human skin cells following the impact of oxidative stress inducers and the ability of idebenone and nicotinamide to mitigate these responses2014
Dr Amy Bowman
Professor Mark Birch-Machin
The simultaneous detection of mitochondrial DNA damage from sun-exposed skin of three whale species and its association with UV-induced microscopic lesions and apoptosis2013
Professor Mark Birch-Machin
Dr Robert Ellis
Dr Jane Renwick
Professor Penny Lovat
Increasing the therapeutic efficacy of docetaxel for cutaneous squamous cell carcinoma through the combined inhibition of phosphatidylinositol 3-kinase/AKT signalling and autophagy2013
Professor Mark Birch-Machin
Dr Jennifer Latimer
Mitochondrial DNA damage as a biomarker for ultraviolet radiation exposure and oxidative stress2013
Dr Asif Tulah
Professor Mark Birch-Machin
Stressed out mitochondria: The role of mitochondria in ageing and cancer focussing on strategies and opportunities in human skin2013
Mohammed Asim
Dr Edward Okello
Professor Mark Birch-Machin
Professor Georg Lietz
The anti-oxidant capacity of green tea polyphenols in the oral cavity2013
Professor Mark Birch-Machin
Dr Andrew Harbottle
The role of mitochondrial DNA damage in skin carcinogenesis and aging2013
Dr Amy Bowman
Professor Mark Birch-Machin
The simultaneous detection of mitochondrial DNA damage from sun-exposed skin of three whale species and its association with UV-induced microscopic lesions and apoptosis2013
Professor Mark Birch-Machin
Dr Amy Bowman
Whales Use Distinct Strategies to Counteract Solar Ultraviolet Radiation2013
Dr Jennifer Latimer
Dr Anne Oyewole
Professor Mark Birch-Machin
Investigating the Protective Potential of the Antioxidant Tiron in Human Skin Cells Exposed to Ultraviolet Radiation2012
Dr Helen Swalwell
Dr Jennifer Latimer
Professor Mark Birch-Machin
Investigating the role of melanin in UVA/B- and hydrogen peroxide-induced cellular and mitochondrial ROS production and mitochondrial DNA damage in human melanoma cells2012
Dr Amy Bowman
Professor Mark Birch-Machin
Mitochondrial DNA, a reliable biomarker for measuring the effect of cumulative ultraviolet irradiation exposure in whales (cetaceans)2012
Dr Jennifer Latimer
Professor Mark Birch-Machin
The Effects of Infrared Radiation versus Ultraviolet Radiation in Human Skin Cells2012
Alasdair Anderson
Dr SarahJayne Boulton
Dr Helen Swalwell
Dr James Henderson
Dr Philip Manning
et al.
Implications of using ROS sensitive probes in studies of UVA induced ROS in skin cells2011
Dr SarahJayne Boulton
Alasdair Anderson
Dr Helen Swalwell
Dr James Henderson
Dr Philip Manning
et al.
Implications of using the fluorescent probes, dihydrorhodamine 123 and 2 ',7 '-dichlorodihydrofluorescein diacetate, for the detection of UVA-induced reactive oxygen species2011
Dr Christine Challen
Professor Philip Sloan
Professor Mark Birch-Machin
Dr Max Robinson
Mitochondrial DNA mutations in head and neck cancer are infrequent and lack prognostic utility2011
Dr Helen Swalwell
Professor Mark Birch-Machin
Oxidative stress in human melanoma skin cells and its relationship with mitochondrial DNA damage and pigmentation2011
Dr Helen Swalwell
Dr SarahJayne Boulton
Dr Philip Manning
Emeritus Professor Calum McNeil
Professor Mark Birch-Machin
et al.
Real time electrochemical measurement of oxidative stress in human melanoma skin cells and its relationship with mitochondrial DNA damage and pigmentation2011
Dr Helen Swalwell
Professor Mark Birch-Machin
Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness2011
Dr Jennifer Latimer
Dr James Lloyd
Professor Mark Birch-Machin
The action spectrum of UVR-induced damage within an 11 kb segment of mitochondrial DNA in human skin cells2011
Dr Anne Oyewole
Amy Bowman
Theon Rogers
Professor Mark Birch-Machin
The role, mechanism and protective effects of dietary antioxidants in human skin subjected to inducers of oxidative stress2011
Dr Andrew Harbottle
Professor Mark Birch-Machin
Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial2011
Professor Mark Birch-Machin
Dr Helen Swalwell
How mitochondria record the effects of UV exposure and oxidative stress using human skin as a model tissue2010
Dr Helen Swalwell
Dr Anne Oyewole
Matthew Birket
Professor Georg Lietz
Professor Mark Birch-Machin
et al.
Investigating the effects of mitochondrial-targeted antioxidants on mitochondrial function and DNA damage in human skin cells2010
Dr Anne Oyewole
Professor Mark Birch-Machin
Investigation of the protective effects of dietary antioxidants in human skin subjected to inducers of oxidative stress2010
Dr Helen Swalwell
Dr James Henderson
Dr SarahJayne Boulton
Dr Philip Manning
Emeritus Professor Calum McNeil
et al.
Oxidative stress in skin cells and its association with mitochondrial damage and skin cancer2010
Alasdair Anderson
Dr SarahJayne Boulton
Dr Helen Swalwell
Dr James Henderson
Dr Philip Manning
et al.
Potential pitfalls of measuring cellular oxidative stress using fluorescent probes, and the contribution of the individual mitochondrial respiratory chain complexes to oxidative stress generation in human skin2010
Dr Andrew Harbottle
Professor Mark Birch-Machin
Real-time polymerase chain reaction analysis of a 3895-bp mitochondrial DNA deletion in epithelial swabs and its use as a quantitative marker for sunlight exposure in human skin2010
Shaun Martin
Dr David Hill
Professor Mark Birch-Machin
Professor Penny Lovat
Dr Chris Redfern
et al.
Targeting GRP78 to enhance melanoma cell death2010
Dr Emma Hiscutt
Dr David Hill
Shaun Martin
Dr Andrew Harbottle
Professor Mark Birch-Machin
et al.
Targeting X-Linked Inhibitor of Apoptosis Protein to Increase the Efficacy of Endoplasmic Reticulum Stress-Induced Apoptosis for Melanoma Therapy2010
Dr David Hill
Shaun Martin
Dr Jane Renwick
Dr Ross Flockhart
Dominic Simpson
et al.
Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma2009
Dr James Henderson
Dr Helen Swalwell
Dr SarahJayne Boulton
Dr Philip Manning
Emeritus Professor Calum McNeil
et al.
Direct, real-time monitoring of superoxide generation in isolated mitochondria2009
Professor Penny Lovat
Dr Jane Renwick
Shaun Martin
Dr David Hill
Dr Chris Redfern
et al.
Increasing Melanoma Cell Death Using Inhibitors of Protein Disulphide Isomerases to Abrogate Survival Responses to Endoplasmic Reticulum Stress2009
Matthew Birket
Dr Joao Passos
Professor Thomas von Zglinicki
Professor Mark Birch-Machin
The Relationship between the Aging- and Photo-Dependent T414G Mitochondrial DNA Mutation with Cellular Senescence and Reactive Oxygen Species Production in Cultured Skin Fibroblasts2009
Dr Anne Oyewole
Matthew Birket
Diana Levett
Dr Mark Anderson
Dr Helen Swalwell
et al.
The use of mitochondrial DNA to determine the role, mechanism and protective effects of antioxidants in human skin2009
Professor Mark Birch-Machin
Dr Anne Oyewole
Alasdair Anderson
Dr SarahJayne Boulton
Dr Philip Manning
et al.
The use of nanosensors and mitochondrial DNA to investigate oxidative stress and aging in human skin2009
Alasdair Anderson
Dr Gillian Aitken
Dr Anne Oyewole
Dr Helen Swalwell
Jill Henderson
et al.
To determine the relative roles of the different mitochondrial respiratory chain complexes in the production of oxidative stress in human skin2009
Professor Mark Birch-Machin
Assessment of Mitochondrial Respiratory Complex Function In Vitro and In Vivo2008
Dr David Hill
Dr Jane Renwick
Professor Mark Birch-Machin
Professor Penny Lovat
B-RAF signalling in endoplasmic reticulum stress-induced apoptosis of metastatic melanoma2008
Shaun Martin
Dr David Hill
Dr Jane Renwick
Professor Mark Birch-Machin
Dr Chris Redfern
et al.
Combining endoplasmic reticulum stress-inducing agents with protein disulphide isomerase inhibition: a novel therapeutic strategy for metastatic melanoma2008
Professor Penny Lovat
Shaun Martin
Dr Jane Renwick
Dr Chris Redfern
Professor Mark Birch-Machin
et al.
Combining ER-stress-induced apoptosis with protein disulphide isomerase inhibition as a novel therapeutic strategy for metastatic melanoma2008
Diana Levett
Shaun Martin
Professor Penny Lovat
Professor Mark Birch-Machin
Endoplasmic reticulum stress-induced apoptosis in response to imiquimod: a novel therapeutic strategy for metastatic squamous cell carcinoma?2008
Professor Penny Lovat
Dr Jane Renwick
Shaun Martin
Dr David Hill
Professor Mark Birch-Machin
et al.
Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress2008
Matthew Birket
Dr Joao Passos
Professor Thomas von Zglinicki
Professor Mark Birch-Machin
Investigation of the relationship between the ageing- and photodependent T414G mitochondrial DNA mutation with cellular senescence and reactive oxygen species production in cultured skin fibroblasts2008
Dr Andrew Harbottle
Professor Mark Birch-Machin
Lycopene protects against biomarkers of photodamage in human skin2008
Professor Mark Birch-Machin
Skin photobiology2008
Dr Saeed Ahmed
Dr Joao Passos
Matthew Birket
Dr Heiko Peters
Professor Mark Birch-Machin
et al.
Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress2008
Dr Andrew Harbottle
Professor Mark Birch-Machin
Dr Jameel Maki
The use of mitochondrial DNA as a "Biosensor" for UVR induced skin damage: Implications for personalized sun care and effective product formulation2008
Professor Mark Birch-Machin
Clinical implications and utility of field cancerization2007
Professor Penny Lovat
Dr Chris Redfern
Professor Mark Birch-Machin
Combining endoplasmic reticulum stress-inducing agents with protein disulphide isomerase inhibitors as a novel therapeutic strategy for metastatic melanoma2007
Professor Penny Lovat
Dr Chris Redfern
Professor Mark Birch-Machin
Combining ER-stress inducing agents with protein disulphide inhibitors as a novel therapeutic strategy for metastatic melanoma2007
Dr Andrew Harbottle
Professor Mark Birch-Machin
Cutaneous photoprotection by dietary tomato product2007
Dr David Hill
Dr Jane Renwick
Professor Mark Birch-Machin
Professor Penny Lovat
Defining the role of B-RAF-induced extracellular signal-related kinase in the resistance of metastatic melanoma to apoptosis2007
Dr Gillian Aitken
Dr James Henderson
Dr Seung Chang
Emeritus Professor Calum McNeil
Professor Mark Birch-Machin
et al.
Direct monitoring of UV-induced free radical generation in HaCaT keratinocytes2007
Professor Mark Birch-Machin
Management of field change in actinic keratosis2007
Dr Joao Passos
Dr Gabriele Saretzki
Dr Saeed Ahmed
Dr Glyn Nelson
Torsten Richter
et al.
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence2007
Professor Penny Lovat
Dr Jane Renwick
Dr David Hill
Professor Mark Birch-Machin
Dr Chris Redfern
et al.
Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: The role of stress proteins ERdj5 and ERp572007
Matthew Birket
Professor Mark Birch-Machin
Dr Saeed Ahmed
Dr Gabriele Saretzki
Telomerase-dependent protection of mitochondrial DNA in response to oxidative stress2007
Professor Mark Birch-Machin
The mitochondrial genome: a biosensor for early cancer detection?2007
Matthew Birket
Professor Mark Birch-Machin
Ultraviolet radiation exposure accelerates the accumulation of the aging-dependent T414G mitochondrial DNA mutation in human skin2007
Matthew Birket
Professor Thomas von Zglinicki
Professor Mark Birch-Machin
A photoageing-associated mitochondrial DNA mutation with potential functional consequences2006
Professor Penny Lovat
Dr Andrew Harbottle
Dr Chris Redfern
Professor Mark Birch-Machin
Fenretinide-induced apoptosis via endoplasmic reticulum stress - new drug targets for melanoma therapy?2006
Professor Mark Birch-Machin
Mitochondrial DNA as a potential tool for early cancer detection2006
Dr Andrew Harbottle
Professor Mark Birch-Machin
Real-time PCR analysis of a 3895 bp mitochondrial DNA deletion in nonmelanoma skin cancer and its use as a quantitative marker for sunlight exposure in human skin2006
Professor Mark Birch-Machin
Somatic mitochondrial DNA mutations in prostate cancer and normal appearing adjacent glands in comparison to age-matched prostate samples without malignant histology2006
Professor Mark Birch-Machin
The dying melanocyte in the aging hair follicle displays oxidative stress damage: a model for tissue-specific aging2006
Professor Mark Birch-Machin
The incidence of both tandem duplications and the common deletion in mtDNA from three distinct categories of sun-exposed human skin and in prolonged culture of fibroblasts2006
Professor Mark Birch-Machin
The role of mitochondria in ageing and carcinogenesis2006
Professor Mark Birch-Machin
Towards a "free radical theory of graying": Melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage2006
Professor Nick Reynolds
Dr Adrian Frank
Lindi Skitt
Emeritus Professor Doug Turnbull
Professor Mark Birch-Machin
et al.
Anthralin interacts with the Q pool and induces cytochrome c release, caspase 3 activation and apoptosis in human keratinocytes2005
Dr James Henderson
Dr Seung Chang
Emeritus Professor Calum McNeil
Professor Mark Birch-Machin
Direct real-time electrochemical measurement and flow cytometry of UVA induced oxidative stress and its perturbation by mitochondrial electron transport chain inhibitors2005
Professor Nick Reynolds
Dr Adrian Frank
Lindi Skitt
Emeritus Professor Doug Turnbull
Professor Mark Birch-Machin
et al.
Dithranol induces cytochrome c release, caspase 3 activation and apoptosis in human keratinocytes2005
Emeritus Professor Doug Turnbull
Professor Mark Birch-Machin
Professor Nick Reynolds
The anti-psoriatic drug anthralin accumulates in keratinocyte mitochondria, dissipates mitochondrial membrane potential, and induces apoptosis through a pathway dependent on respiratory competent mitochondria2005
Professor Mark Birch-Machin
Using mitochondrial DNA as a biosensor of early cancer development2005
Dr Andrew Harbottle
Professor Mark Birch-Machin
Implications of using the ND1 gene as a control region for real-time PCR analysis of mitochondrial DNA deletions in human skin [1]2004
Professor Mark Birch-Machin
Dr Andrew Harbottle
The incidence of a minor arc mitochondrial DNA deletion in human skin cancer and its novel use as a highly sensitive marker for sunlight exposure2004
Kim Krishnan
Dr Andrew Harbottle
Professor Mark Birch-Machin
The use of a 3895 bp mitochondrial DNA deletion as a marker for sunlight exposure in human skin2004
Professor Mark Birch-Machin
A maternal line study investigating the 4977-bp mitochondrial DNA deletion2003
Professor Mark Birch-Machin
A maternal line study investigating the 4977-bp mitochondrial DNA deletion2003
Dr Janet Lindsey
Dr Meryl Lusher
Professor Mark Birch-Machin
Current pitfalls in the measurement of the 4977 bp mitochondrial DNA common deletion in human skin2003
Dr Meryl Lusher
Professor Mark Birch-Machin
Direct generation of the mitochondrial DNA common deletion in cultured skin cells by repetitive ultraviolet irradiation2003
Dr Adrian Frank
Professor Mark Birch-Machin
Professor Nick Reynolds
Mammalian cells deficient in respiratory competent mitochondria are resistant to dithranol2003
Dr Steve Durham
Professor Mark Birch-Machin
Mitochondrial DNA damage in non-melanoma skin cancer2003
Dr Gillian Aitken
Dr Andrew Harbottle
Professor Mark Birch-Machin
The role of mitochondria in ultraviolet-induced oxidative stress2003
Professor Mark Birch-Machin
Emeritus Professor Doug Turnbull
Assaying mitochondrial respiratory complex activity in mitochondria isolated from human cells and tissues2001
Dr Craig Dixon
Dr Amanda Ray
Sion Phillips
William Cunliffe
Dr Simon Meggitt
et al.
Expression, candidate gene, and population studies of the melanocortin 5 receptor2001
Dr Amanda Ray
Carole Todd
Professor Mark Birch-Machin
Professor Jonathan Rees
The relation between melanocortin 1 receptor genotype and experimentally assessed ultraviolet radiation sensitivity2001
Dr Eugene Healy
Dr Amanda Ray
Dr Niamh Flanagan
Carole Todd
Professor Mark Birch-Machin
et al.
Evidence for variable selective pressures at MC1R2000
Professor Mark Birch-Machin
Professor Robert Taylor
Emeritus Professor Doug Turnbull
Late-onset optic atrophy, ataxia, and myopathy associated with a mutation of a complex II gene2000
Dr Eugene Healy
Dr Amanda Ray
Professor John Matthews
Professor Mark Birch-Machin
Professor Jonathan Rees
et al.
Melanocortin-1-receptor gene and sun sensitivity in individuals without red hair2000
Professor Mark Birch-Machin
Mitochondria and skin disease2000
Dr Niamh Flanagan
Dr Eugene Healy
Dr Amanda Ray
Carole Todd
Professor Mark Birch-Machin
et al.
Pleiotropic effects of the melanocortin 1 receptor (MC1R) gene on human pigmentation2000
Dr Eugene Healy
Professor Mark Birch-Machin
Professor Jonathan Rees
The Human Melanocortin1-Receptor Gene2000
Dr Amanda Ray
Professor Jonathan Rees
Professor Mark Birch-Machin
The spectrum of mitochondrial DNA deletions is a ubiquitous marker of ultraviolet radiation exposure in human skin2000
Dr Eugene Healy
Professor Mark Birch-Machin
Professor Jonathan Rees
Distinct mutations in human basic hair keratins 1 and 6 cause monilethrix: Implications for protein structure and clinical phenotype1999
Professor Jonathan Rees
Professor Mark Birch-Machin
Dr Niamh Flanagan
Dr Eugene Healy
Genetic studies of the human melanocortin-1 receptor1999
Professor Jonathan Rees
Professor Mark Birch-Machin
Dr Niamh Flanagan
Dr Eugene Healy
Genetic studies of the human melanocortin-1 receptor1999
Dr Niamh Flanagan
Dr Eugene Healy
Dr Amanda Ray
Professor Mark Birch-Machin
Heterozygote mutants of the melanocortin 1 receptor show reduced tanning whilst homozyotes show red hair1999
Dr Eugene Healy
Professor Mark Birch-Machin
Professor Jonathan Rees
Identification of novel mutations in basic hair keratins hHb1 and hHb6 in monilethrix: Implications for protein structure and clinical phenotype1999
Professor Mark Birch-Machin
Professor Jonathan Rees
Loss of function mutations of the human melanocortin 1 receptor are common and are associated with red hair.1999
Dr Amanda Ray
Dr Niamh Flanagan
Professor Mark Birch-Machin
Professor Jonathan Rees
Low frequency of genetic change in p53 immunopositive clones in human epidermis1999
Dr Amanda Ray
Dr Eugene Healy
Carein Todd
Dr Niamh Flanagan
Professor Mark Birch-Machin
et al.
Molecular genetic evidence for evolutionary selection of the red hair (MC1R) phenotype1999
Dr Eugene Healy
Professor Mark Birch-Machin
Professor Jonathan Rees
Catriona Munro
Point mutation in the helix termination peptide (HTP) of human type II hair keratin hHb6 causes monilethrix in five families1999
Dr Eugene Healy
Professor Mark Birch-Machin
Point mutations in the 1A domain (N114) of hair keratin hHb6 in monilethrix patients: A new hotspot for mutations?1999
Professor Mark Birch-Machin
Riboflavine-response Leigh syndrome and leukodystrophy associated to partial succinate dehydrogenase deficiency1999
Dr Eugene Healy
Carole Todd
Professor Mark Birch-Machin
Professor Jonathan Rees
Skin type, melanoma, and melanocortin 1 receptor variants1999
Professor Mark Birch-Machin
Faye Haldane
Professor Jonathan Rees
Mitochondrial DNA deletions in human skin reflect photo- rather than chronologic aging1998