Professor Mark Birch-Machin Jessica Moor
| Mitochondria as a Skin Health Biomarker | 2024 |
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Professor Mark Birch-Machin
| Skin Life Analytics: A pro-ageing skin test for Aesthetic Clinics | 2024 |
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Wil Reynolds Dr Ndubuisi Eje Professor Paul Christensen Professor Mark Birch-Machin
| Biological effects of air pollution on the function of human skin equivalents | 2023 |
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Jessica Moor Professor Mark Birch-Machin
| Bioenergy and stressed out skin; what can we do? | 2022 |
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Professor Mark Birch-Machin
| Targeting mitochondria in dermatological therapy: beyond oxidative damage and skin aging | 2022 |
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Wil Reynolds Dr Amy Bowman Dr Peter Hanson Professor Mark Birch-Machin
| Adaptive responses to air pollution in human dermal fibroblasts and their potential roles in ageing | 2021 |
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Dr Eyman Rashdan Dr Khimara Naidoo Professor Mark Birch-Machin
| Distinctive clinical and histological characteristics of atrophic and hypertrophic facial photoageing | 2021 |
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Becky Zhu Dr Sophie Cassidy Dr Hugo Hiden Professor Mike Trenell Professor Mike Catt et al. | Exploration of sleep as a specific risk factor for poor metabolic and mental health: a UK Biobank study of 84,404 participants | 2021 |
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Rach Dixon Dr Wing Man Lau Dr Philip Manning Professor Mark Birch-Machin Professor Moein Moghimi et al. | Microneedle-based devices for point-of-care infectious disease diagnostics | 2021 |
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Dr Amy Bowman Professor Mark Birch-Machin
| Mitochondrial DNA as a sensitive biomarker of UV-Induced Cellular Damage in Human Skin | 2021 |
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Professor Mark Birch-Machin
| The Inhibition of Metabolic Inflammation by EPA is Associated with Enhanced Mitochondrial Fusion and Insulin Signalling in Human Primary Myotubes | 2021 |
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Wil Reynolds Dr Peter Hanson Professor Mark Birch-Machin
| Exposing human primary dermal fibroblasts to particulate matter induces changes associated with skin aging | 2020 |
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Laura Hudson Dr Eyman Rashdan Catherine Bonn David Rawlings Professor Mark Birch-Machin et al. | Individual and combined effects of the infrared, visible and ultraviolet light components of solar radiation on damage biomarkers in human skin cells | 2020 |
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Dr Amy Bowman Dr Glyn Nelson Professor Mark Birch-Machin
| Metabolic dysfunction in human skin: Restoration of mitochondrial integrity and metabolic output by nicotinamide (niacinamide) in primary dermal fibroblasts from older aged donors | 2020 |
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Roisin Stout Professor Mark Birch-Machin
| Mitochondria's role in skin ageing | 2019 |
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Becky Zhu Professor Mike Catt Dr Sophie Cassidy Professor Mark Birch-Machin Professor Mike Trenell et al. | Objective sleep assessment in >80,000 UK mid-life adults: associations with sociodemographic characteristics, physical activity and caffeine | 2019 |
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Rebecca Hanna David Moore Professor Mark Birch-Machin
| Optimised detection of mitochondrial DNA strand breaks | 2019 |
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Professor Mark Birch-Machin
| The Mitochondria and Complex II- Linchpin for skin ageing and photoaging | 2019 |
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Dr Tom Clifford Dr Amy Bowman Tess Capper Dr Dean Allerton Dr Emma Foster et al. | A pilot study investigating reactive oxygen species production in capillary blood after a marathon and the influence of an antioxidant-rich beetroot juice. | 2018 |
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Nik Zakaria Dr Edward Okello Professor Mark Birch-Machin Dr Amy Bowman
| In vitro protective effects of an aqueous extract of Clitoria ternatea L. flower against hydrogen peroxide-induced cytotoxicity and UV-induced mtDNA damage in human keratinocytes | 2018 |
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Dr Amy Bowman Professor Mark Birch-Machin
| Nicotinamide enhances mitochondrial function in human skin cells | 2018 |
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Catherine Bonn Dr Khimara Naidoo Professor Mark Birch-Machin
| Sunlight,diet and pollution- effects on oxidative stress and skin ageing | 2018 |
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Professor Mark Birch-Machin Dr Ellen Hatch
| Tiron is Protective Against ROS-Induced Damage in Human Bronchial Epithelial Cells | 2018 |
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Professor Mark Birch-Machin
| UVA-induced Carbon-Centered Radicals in Lightly Pigmented Cells detected using ESR Spectroscopy | 2018 |
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Dr Khimara Naidoo Rebecca Hanna Professor Mark Birch-Machin
| What is the role of mitochondrial dysfunction in skin photoaging? | 2018 |
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Dr Angela Rodrigues Professor Falko Sniehotta Professor Mark Birch-Machin Professor Vera Araujo-Soares
| Aware, motivated and striving for a ‘safe tan’: an exploratory mixed-method study of sun-protection during holidays | 2017 |
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Laura Hudson Dr Khimara Naidoo Dr Simon Wilkinson Professor Mark Birch-Machin
| Bad air gets under your skin | 2017 |
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Dr Khimara Naidoo Professor Mark Birch-Machin
| Oxidative Stress and Ageing: The Influence of Environmental Pollution, Sunlight and Diet on Skin | 2017 |
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Dr Angela Rodrigues Professor Falko Sniehotta Professor Mark Birch-Machin Professor Vera Araujo-Soares
| Systematic and iterative development of a smartphone application to promote sun-protection amongst holidaymaker | 2017 |
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Dr Amy Bowman Professor Mark Birch-Machin
| Age-dependent decrease of mitochondrial complex II activity in human skin fibroblasts | 2016 |
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Dr Amy Bowman Professor Mark Birch-Machin
| Cosmetic sunscreen formulations provide protection against UVR-induced mitochondrial DNA damage in human skin cells | 2016 |
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Laura Hudson Dr Amy Bowman Dr Eyman Rashdan Professor Mark Birch-Machin
| Mitochondrial damage and ageing using skin as a model organ | 2016 |
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Professor Mark Birch-Machin Dr Amy Bowman
| Oxidative stress and ageing | 2016 |
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Dr Jennifer Latimer Dr James Lloyd Emeritus Professor Brian Diffey Professor Mark Birch-Machin
| Determination of the action spectrum of UVR-induced mitochondrial DNA damage in human skin cells | 2015 |
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Dr SarahJayne Boulton Professor Mark Birch-Machin
| Impact of hyperpigmentation on superoxide flux and melanoma cell metabolism at mitochondrial complex II. | 2015 |
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Dr Amy Bowman Professor Mark Birch-Machin
| Mitochondrial DNA as a Biosensor of UV Exposure in Human Skin. | 2015 |
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Dr Anne Oyewole Professor Mark Birch-Machin
| Mitochondrial-targeted antioxidants | 2015 |
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Dr Amy Bowman Professor Mark Birch-Machin
| Oxidative stress - a key emerging impact factor in health, ageing, lifestyle and aesthetics | 2015 |
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Dr Anne Oyewole Professor Mark Birch-Machin
| Sebum, Inflammasomes and the Skin: current concepts and future perspective | 2015 |
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Dr SarahJayne Boulton Dr Amy Bowman Roxanna Koohgoli Professor Mark Birch-Machin
| Skin manifestations of mitochondrial dysfunction: more important than previously thought | 2015 |
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Dr Amy Bowman Professor Mark Birch-Machin Professor Georg Lietz
| The Effect Of Nutritional Intervention On Blood Oxidative Stress Levels | 2015 |
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Dr SarahJayne Boulton Professor Mark Birch-Machin
| The impact of hyperpigmentation on mitochondria: a comparative approach to investigating bioenergetic pathways in melanoma and keratinocyte cell types | 2015 |
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Alasdair Anderson Dr Amy Bowman Dr SarahJayne Boulton Dr Philip Manning Professor Mark Birch-Machin et al. | A role for human mitochondrial complex II in the production of reactive oxygen species in human skin | 2014 |
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Dr Angela Rodrigues Professor Falko Sniehotta Professor Mark Birch-Machin Professor Vera Araujo-Soares
| Acceptability and feasibility of a mobile-phone intervention to promote sun safe behaviors amongst holidaymakers: findings from the internal pilot of the miskin randomized trial | 2014 |
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Dr Amy Bowman Dr Philip Manning Professor Mark Birch-Machin
| Applicability of dermoscopy for evaluation of patients' response to nonablative therapies for the treatment of superficial basal cell carcinoma | 2014 |
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Dr Anne Oyewole Professor Mark Birch-Machin
| Comparing the effects of mitochondrial targeted and localized antioxidants with cellular antioxidants in human skin cells exposed to UVA and hydrogen peroxide | 2014 |
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Professor Mark Birch-Machin
| Effects of polyphenols on mitochondrial DNA damage in skin fibroblasts | 2014 |
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Dr SarahJayne Boulton Professor Mark Birch-Machin
| Melanin reduces acute mitochondrial superoxide generation: a real-time amperometric study | 2014 |
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Dr Amy Bowman Professor Mark Birch-Machin
| Responses to acute sun exposure in large whales | 2014 |
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Dr Amy Bowman Professor Mark Birch-Machin Dr SarahJayne Boulton
| The roles of the mitochondrial respiratory chain complexes in UVA-induced oxidative stress in human skin cells compared to other cell types | 2014 |
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Dr Jennifer Latimer Professor Mark Birch-Machin
| Using the Seahorse XF Analyser to evaluate real-time cellular respiration of human skin cells following the impact of oxidative stress inducers and the ability of idebenone and nicotinamide to mitigate these responses | 2014 |
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Dr Amy Bowman Professor Mark Birch-Machin
| The simultaneous detection of mitochondrial DNA damage from sun-exposed skin of three whale species and its association with UV-induced microscopic lesions and apoptosis | 2013 |
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Professor Mark Birch-Machin Dr Robert Ellis Dr Jane Renwick Professor Penny Lovat
| Increasing the therapeutic efficacy of docetaxel for cutaneous squamous cell carcinoma through the combined inhibition of phosphatidylinositol 3-kinase/AKT signalling and autophagy | 2013 |
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Professor Mark Birch-Machin Dr Jennifer Latimer
| Mitochondrial DNA damage as a biomarker for ultraviolet radiation exposure and oxidative stress | 2013 |
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Dr Asif Tulah Professor Mark Birch-Machin
| Stressed out mitochondria: The role of mitochondria in ageing and cancer focussing on strategies and opportunities in human skin | 2013 |
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Mohammed Asim Dr Edward Okello Professor Mark Birch-Machin Professor Georg Lietz
| The anti-oxidant capacity of green tea polyphenols in the oral cavity | 2013 |
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Professor Mark Birch-Machin Dr Andrew Harbottle
| The role of mitochondrial DNA damage in skin carcinogenesis and aging | 2013 |
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Dr Amy Bowman Professor Mark Birch-Machin
| The simultaneous detection of mitochondrial DNA damage from sun-exposed skin of three whale species and its association with UV-induced microscopic lesions and apoptosis | 2013 |
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Professor Mark Birch-Machin Dr Amy Bowman
| Whales Use Distinct Strategies to Counteract Solar Ultraviolet Radiation | 2013 |
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Dr Jennifer Latimer Dr Anne Oyewole Professor Mark Birch-Machin
| Investigating the Protective Potential of the Antioxidant Tiron in Human Skin Cells Exposed to Ultraviolet Radiation | 2012 |
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Dr Helen Swalwell Dr Jennifer Latimer Professor Mark Birch-Machin
| Investigating the role of melanin in UVA/B- and hydrogen peroxide-induced cellular and mitochondrial ROS production and mitochondrial DNA damage in human melanoma cells | 2012 |
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Dr Amy Bowman Professor Mark Birch-Machin
| Mitochondrial DNA, a reliable biomarker for measuring the effect of cumulative ultraviolet irradiation exposure in whales (cetaceans) | 2012 |
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Dr Jennifer Latimer Professor Mark Birch-Machin
| The Effects of Infrared Radiation versus Ultraviolet Radiation in Human Skin Cells | 2012 |
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Alasdair Anderson Dr SarahJayne Boulton Dr Helen Swalwell Dr James Henderson Dr Philip Manning et al. | Implications of using ROS sensitive probes in studies of UVA induced ROS in skin cells | 2011 |
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Dr SarahJayne Boulton Alasdair Anderson Dr Helen Swalwell Dr James Henderson Dr Philip Manning et al. | Implications of using the fluorescent probes, dihydrorhodamine 123 and 2 ',7 '-dichlorodihydrofluorescein diacetate, for the detection of UVA-induced reactive oxygen species | 2011 |
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Dr Christine Challen Professor Philip Sloan Professor Mark Birch-Machin Dr Max Robinson
| Mitochondrial DNA mutations in head and neck cancer are infrequent and lack prognostic utility | 2011 |
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Dr Helen Swalwell Professor Mark Birch-Machin
| Oxidative stress in human melanoma skin cells and its relationship with mitochondrial DNA damage and pigmentation | 2011 |
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Dr Helen Swalwell Dr SarahJayne Boulton Dr Philip Manning Emeritus Professor Calum McNeil Professor Mark Birch-Machin et al. | Real time electrochemical measurement of oxidative stress in human melanoma skin cells and its relationship with mitochondrial DNA damage and pigmentation | 2011 |
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Dr Helen Swalwell Professor Mark Birch-Machin
| Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness | 2011 |
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Dr Jennifer Latimer Dr James Lloyd Professor Mark Birch-Machin
| The action spectrum of UVR-induced damage within an 11 kb segment of mitochondrial DNA in human skin cells | 2011 |
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Dr Anne Oyewole Amy Bowman Theon Rogers Professor Mark Birch-Machin
| The role, mechanism and protective effects of dietary antioxidants in human skin subjected to inducers of oxidative stress | 2011 |
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Dr Andrew Harbottle Professor Mark Birch-Machin
| Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial | 2011 |
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Professor Mark Birch-Machin Dr Helen Swalwell
| How mitochondria record the effects of UV exposure and oxidative stress using human skin as a model tissue | 2010 |
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Dr Helen Swalwell Dr Anne Oyewole Matthew Birket Professor Georg Lietz Professor Mark Birch-Machin et al. | Investigating the effects of mitochondrial-targeted antioxidants on mitochondrial function and DNA damage in human skin cells | 2010 |
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Dr Anne Oyewole Professor Mark Birch-Machin
| Investigation of the protective effects of dietary antioxidants in human skin subjected to inducers of oxidative stress | 2010 |
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Dr Helen Swalwell Dr James Henderson Dr SarahJayne Boulton Dr Philip Manning Emeritus Professor Calum McNeil et al. | Oxidative stress in skin cells and its association with mitochondrial damage and skin cancer | 2010 |
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Alasdair Anderson Dr SarahJayne Boulton Dr Helen Swalwell Dr James Henderson Dr Philip Manning et al. | Potential pitfalls of measuring cellular oxidative stress using fluorescent probes, and the contribution of the individual mitochondrial respiratory chain complexes to oxidative stress generation in human skin | 2010 |
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Dr Andrew Harbottle Professor Mark Birch-Machin
| Real-time polymerase chain reaction analysis of a 3895-bp mitochondrial DNA deletion in epithelial swabs and its use as a quantitative marker for sunlight exposure in human skin | 2010 |
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Shaun Martin Dr David Hill Professor Mark Birch-Machin Professor Penny Lovat Dr Chris Redfern et al. | Targeting GRP78 to enhance melanoma cell death | 2010 |
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Dr Emma Hiscutt Dr David Hill Shaun Martin Dr Andrew Harbottle Professor Mark Birch-Machin et al. | Targeting X-Linked Inhibitor of Apoptosis Protein to Increase the Efficacy of Endoplasmic Reticulum Stress-Induced Apoptosis for Melanoma Therapy | 2010 |
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Dr David Hill Shaun Martin Dr Jane Renwick Dr Ross Flockhart Dominic Simpson et al. | Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma | 2009 |
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Dr James Henderson Dr Helen Swalwell Dr SarahJayne Boulton Dr Philip Manning Emeritus Professor Calum McNeil et al. | Direct, real-time monitoring of superoxide generation in isolated mitochondria | 2009 |
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Professor Penny Lovat Dr Jane Renwick Shaun Martin Dr David Hill Dr Chris Redfern et al. | Increasing Melanoma Cell Death Using Inhibitors of Protein Disulphide Isomerases to Abrogate Survival Responses to Endoplasmic Reticulum Stress | 2009 |
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Matthew Birket Dr Joao Passos Professor Thomas von Zglinicki Professor Mark Birch-Machin
| The Relationship between the Aging- and Photo-Dependent T414G Mitochondrial DNA Mutation with Cellular Senescence and Reactive Oxygen Species Production in Cultured Skin Fibroblasts | 2009 |
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Dr Anne Oyewole Matthew Birket Diana Levett Dr Mark Anderson Dr Helen Swalwell et al. | The use of mitochondrial DNA to determine the role, mechanism and protective effects of antioxidants in human skin | 2009 |
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Professor Mark Birch-Machin Dr Anne Oyewole Alasdair Anderson Dr SarahJayne Boulton Dr Philip Manning et al. | The use of nanosensors and mitochondrial DNA to investigate oxidative stress and aging in human skin | 2009 |
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Alasdair Anderson Dr Gillian Aitken Dr Anne Oyewole Dr Helen Swalwell Jill Henderson et al. | To determine the relative roles of the different mitochondrial respiratory chain complexes in the production of oxidative stress in human skin | 2009 |
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Professor Mark Birch-Machin
| Assessment of Mitochondrial Respiratory Complex Function In Vitro and In Vivo | 2008 |
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Dr David Hill Dr Jane Renwick Professor Mark Birch-Machin Professor Penny Lovat
| B-RAF signalling in endoplasmic reticulum stress-induced apoptosis of metastatic melanoma | 2008 |
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Shaun Martin Dr David Hill Dr Jane Renwick Professor Mark Birch-Machin Dr Chris Redfern et al. | Combining endoplasmic reticulum stress-inducing agents with protein disulphide isomerase inhibition: a novel therapeutic strategy for metastatic melanoma | 2008 |
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Professor Penny Lovat Shaun Martin Dr Jane Renwick Dr Chris Redfern Professor Mark Birch-Machin et al. | Combining ER-stress-induced apoptosis with protein disulphide isomerase inhibition as a novel therapeutic strategy for metastatic melanoma | 2008 |
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Diana Levett Shaun Martin Professor Penny Lovat Professor Mark Birch-Machin
| Endoplasmic reticulum stress-induced apoptosis in response to imiquimod: a novel therapeutic strategy for metastatic squamous cell carcinoma? | 2008 |
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Professor Penny Lovat Dr Jane Renwick Shaun Martin Dr David Hill Professor Mark Birch-Machin et al. | Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress | 2008 |
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Matthew Birket Dr Joao Passos Professor Thomas von Zglinicki Professor Mark Birch-Machin
| Investigation of the relationship between the ageing- and photodependent T414G mitochondrial DNA mutation with cellular senescence and reactive oxygen species production in cultured skin fibroblasts | 2008 |
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Dr Andrew Harbottle Professor Mark Birch-Machin
| Lycopene protects against biomarkers of photodamage in human skin | 2008 |
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Professor Mark Birch-Machin
| Skin photobiology | 2008 |
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Dr Saeed Ahmed Dr Joao Passos Matthew Birket Dr Heiko Peters Professor Mark Birch-Machin et al. | Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress | 2008 |
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Dr Andrew Harbottle Professor Mark Birch-Machin Dr Jameel Maki
| The use of mitochondrial DNA as a "Biosensor" for UVR induced skin damage: Implications for personalized sun care and effective product formulation | 2008 |
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Professor Mark Birch-Machin
| Clinical implications and utility of field cancerization | 2007 |
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Professor Penny Lovat Dr Chris Redfern Professor Mark Birch-Machin
| Combining endoplasmic reticulum stress-inducing agents with protein disulphide isomerase inhibitors as a novel therapeutic strategy for metastatic melanoma | 2007 |
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Professor Penny Lovat Dr Chris Redfern Professor Mark Birch-Machin
| Combining ER-stress inducing agents with protein disulphide inhibitors as a novel therapeutic strategy for metastatic melanoma | 2007 |
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Dr Andrew Harbottle Professor Mark Birch-Machin
| Cutaneous photoprotection by dietary tomato product | 2007 |
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Dr David Hill Dr Jane Renwick Professor Mark Birch-Machin Professor Penny Lovat
| Defining the role of B-RAF-induced extracellular signal-related kinase in the resistance of metastatic melanoma to apoptosis | 2007 |
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Dr Gillian Aitken Dr James Henderson Dr Seung Chang Emeritus Professor Calum McNeil Professor Mark Birch-Machin et al. | Direct monitoring of UV-induced free radical generation in HaCaT keratinocytes | 2007 |
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Professor Mark Birch-Machin
| Management of field change in actinic keratosis | 2007 |
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Dr Joao Passos Dr Gabriele Saretzki Dr Saeed Ahmed Dr Glyn Nelson Torsten Richter et al. | Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence | 2007 |
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Professor Penny Lovat Dr Jane Renwick Dr David Hill Professor Mark Birch-Machin Dr Chris Redfern et al. | Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: The role of stress proteins ERdj5 and ERp57 | 2007 |
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Matthew Birket Professor Mark Birch-Machin Dr Saeed Ahmed Dr Gabriele Saretzki
| Telomerase-dependent protection of mitochondrial DNA in response to oxidative stress | 2007 |
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Professor Mark Birch-Machin
| The mitochondrial genome: a biosensor for early cancer detection? | 2007 |
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Matthew Birket Professor Mark Birch-Machin
| Ultraviolet radiation exposure accelerates the accumulation of the aging-dependent T414G mitochondrial DNA mutation in human skin | 2007 |
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Matthew Birket Professor Thomas von Zglinicki Professor Mark Birch-Machin
| A photoageing-associated mitochondrial DNA mutation with potential functional consequences | 2006 |
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Professor Penny Lovat Dr Andrew Harbottle Dr Chris Redfern Professor Mark Birch-Machin
| Fenretinide-induced apoptosis via endoplasmic reticulum stress - new drug targets for melanoma therapy? | 2006 |
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Professor Mark Birch-Machin
| Mitochondrial DNA as a potential tool for early cancer detection | 2006 |
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Dr Andrew Harbottle Professor Mark Birch-Machin
| Real-time PCR analysis of a 3895 bp mitochondrial DNA deletion in nonmelanoma skin cancer and its use as a quantitative marker for sunlight exposure in human skin | 2006 |
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Professor Mark Birch-Machin
| Somatic mitochondrial DNA mutations in prostate cancer and normal appearing adjacent glands in comparison to age-matched prostate samples without malignant histology | 2006 |
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Professor Mark Birch-Machin
| The dying melanocyte in the aging hair follicle displays oxidative stress damage: a model for tissue-specific aging | 2006 |
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Professor Mark Birch-Machin
| The incidence of both tandem duplications and the common deletion in mtDNA from three distinct categories of sun-exposed human skin and in prolonged culture of fibroblasts | 2006 |
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Professor Mark Birch-Machin
| The role of mitochondria in ageing and carcinogenesis | 2006 |
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Professor Mark Birch-Machin
| Towards a "free radical theory of graying": Melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage | 2006 |
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Professor Nick Reynolds Dr Adrian Frank Lindi Skitt Emeritus Professor Doug Turnbull Professor Mark Birch-Machin et al. | Anthralin interacts with the Q pool and induces cytochrome c release, caspase 3 activation and apoptosis in human keratinocytes | 2005 |
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Dr James Henderson Dr Seung Chang Emeritus Professor Calum McNeil Professor Mark Birch-Machin
| Direct real-time electrochemical measurement and flow cytometry of UVA induced oxidative stress and its perturbation by mitochondrial electron transport chain inhibitors | 2005 |
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Professor Nick Reynolds Dr Adrian Frank Lindi Skitt Emeritus Professor Doug Turnbull Professor Mark Birch-Machin et al. | Dithranol induces cytochrome c release, caspase 3 activation and apoptosis in human keratinocytes | 2005 |
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Emeritus Professor Doug Turnbull Professor Mark Birch-Machin Professor Nick Reynolds
| The anti-psoriatic drug anthralin accumulates in keratinocyte mitochondria, dissipates mitochondrial membrane potential, and induces apoptosis through a pathway dependent on respiratory competent mitochondria | 2005 |
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Professor Mark Birch-Machin
| Using mitochondrial DNA as a biosensor of early cancer development | 2005 |
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Dr Andrew Harbottle Professor Mark Birch-Machin
| Implications of using the ND1 gene as a control region for real-time PCR analysis of mitochondrial DNA deletions in human skin [1] | 2004 |
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Professor Mark Birch-Machin Dr Andrew Harbottle
| The incidence of a minor arc mitochondrial DNA deletion in human skin cancer and its novel use as a highly sensitive marker for sunlight exposure | 2004 |
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Kim Krishnan Dr Andrew Harbottle Professor Mark Birch-Machin
| The use of a 3895 bp mitochondrial DNA deletion as a marker for sunlight exposure in human skin | 2004 |
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Professor Mark Birch-Machin
| A maternal line study investigating the 4977-bp mitochondrial DNA deletion | 2003 |
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Professor Mark Birch-Machin
| A maternal line study investigating the 4977-bp mitochondrial DNA deletion | 2003 |
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Dr Janet Lindsey Dr Meryl Lusher Professor Mark Birch-Machin
| Current pitfalls in the measurement of the 4977 bp mitochondrial DNA common deletion in human skin | 2003 |
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Dr Meryl Lusher Professor Mark Birch-Machin
| Direct generation of the mitochondrial DNA common deletion in cultured skin cells by repetitive ultraviolet irradiation | 2003 |
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Dr Adrian Frank Professor Mark Birch-Machin Professor Nick Reynolds
| Mammalian cells deficient in respiratory competent mitochondria are resistant to dithranol | 2003 |
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Dr Steve Durham Professor Mark Birch-Machin
| Mitochondrial DNA damage in non-melanoma skin cancer | 2003 |
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Dr Gillian Aitken Dr Andrew Harbottle Professor Mark Birch-Machin
| The role of mitochondria in ultraviolet-induced oxidative stress | 2003 |
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Professor Mark Birch-Machin Emeritus Professor Doug Turnbull
| Assaying mitochondrial respiratory complex activity in mitochondria isolated from human cells and tissues | 2001 |
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Dr Craig Dixon Dr Amanda Ray Sion Phillips William Cunliffe Dr Simon Meggitt et al. | Expression, candidate gene, and population studies of the melanocortin 5 receptor | 2001 |
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Dr Amanda Ray Carole Todd Professor Mark Birch-Machin Professor Jonathan Rees
| The relation between melanocortin 1 receptor genotype and experimentally assessed ultraviolet radiation sensitivity | 2001 |
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Dr Eugene Healy Dr Amanda Ray Dr Niamh Flanagan Carole Todd Professor Mark Birch-Machin et al. | Evidence for variable selective pressures at MC1R | 2000 |
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Professor Mark Birch-Machin Professor Robert Taylor Emeritus Professor Doug Turnbull
| Late-onset optic atrophy, ataxia, and myopathy associated with a mutation of a complex II gene | 2000 |
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Dr Eugene Healy Dr Amanda Ray Professor John Matthews Professor Mark Birch-Machin Professor Jonathan Rees et al. | Melanocortin-1-receptor gene and sun sensitivity in individuals without red hair | 2000 |
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Professor Mark Birch-Machin
| Mitochondria and skin disease | 2000 |
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Dr Niamh Flanagan Dr Eugene Healy Dr Amanda Ray Carole Todd Professor Mark Birch-Machin et al. | Pleiotropic effects of the melanocortin 1 receptor (MC1R) gene on human pigmentation | 2000 |
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Dr Eugene Healy Professor Mark Birch-Machin Professor Jonathan Rees
| The Human Melanocortin1-Receptor Gene | 2000 |
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Dr Amanda Ray Professor Jonathan Rees Professor Mark Birch-Machin
| The spectrum of mitochondrial DNA deletions is a ubiquitous marker of ultraviolet radiation exposure in human skin | 2000 |
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Dr Eugene Healy Professor Mark Birch-Machin Professor Jonathan Rees
| Distinct mutations in human basic hair keratins 1 and 6 cause monilethrix: Implications for protein structure and clinical phenotype | 1999 |
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Professor Jonathan Rees Professor Mark Birch-Machin Dr Niamh Flanagan Dr Eugene Healy
| Genetic studies of the human melanocortin-1 receptor | 1999 |
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Professor Jonathan Rees Professor Mark Birch-Machin Dr Niamh Flanagan Dr Eugene Healy
| Genetic studies of the human melanocortin-1 receptor | 1999 |
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Dr Niamh Flanagan Dr Eugene Healy Dr Amanda Ray Professor Mark Birch-Machin
| Heterozygote mutants of the melanocortin 1 receptor show reduced tanning whilst homozyotes show red hair | 1999 |
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Dr Eugene Healy Professor Mark Birch-Machin Professor Jonathan Rees
| Identification of novel mutations in basic hair keratins hHb1 and hHb6 in monilethrix: Implications for protein structure and clinical phenotype | 1999 |
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Professor Mark Birch-Machin Professor Jonathan Rees
| Loss of function mutations of the human melanocortin 1 receptor are common and are associated with red hair. | 1999 |
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Dr Amanda Ray Dr Niamh Flanagan Professor Mark Birch-Machin Professor Jonathan Rees
| Low frequency of genetic change in p53 immunopositive clones in human epidermis | 1999 |
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Dr Amanda Ray Dr Eugene Healy Carein Todd Dr Niamh Flanagan Professor Mark Birch-Machin et al. | Molecular genetic evidence for evolutionary selection of the red hair (MC1R) phenotype | 1999 |
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Dr Eugene Healy Professor Mark Birch-Machin Professor Jonathan Rees Catriona Munro
| Point mutation in the helix termination peptide (HTP) of human type II hair keratin hHb6 causes monilethrix in five families | 1999 |
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Dr Eugene Healy Professor Mark Birch-Machin
| Point mutations in the 1A domain (N114) of hair keratin hHb6 in monilethrix patients: A new hotspot for mutations? | 1999 |
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Professor Mark Birch-Machin
| Riboflavine-response Leigh syndrome and leukodystrophy associated to partial succinate dehydrogenase deficiency | 1999 |
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Dr Eugene Healy Carole Todd Professor Mark Birch-Machin Professor Jonathan Rees
| Skin type, melanoma, and melanocortin 1 receptor variants | 1999 |
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Professor Mark Birch-Machin Faye Haldane Professor Jonathan Rees
| Mitochondrial DNA deletions in human skin reflect photo- rather than chronologic aging | 1998 |
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