The Synthetic Biology Open Language

Myers, C; Clancy, K; Misirli, G; Oberortner, E; Pocock, M; Quinn, J; Roehner, N; Sauro, HM

doi:10.1007/978-1-4939-1878-2_16

The Synthetic Biology Open Language

Lookup NU author(s): Dr Goksel Misirli, Dr Matthew Pocock

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Abstract

he design and construction of engineered organisms is an emerging new discipline called synthetic biology and holds considerable promise as a new technological platform. The design of biologically engineered systems is however nontrivial, requiring contributions from a wide array of disciplines. One particular issue that confronts synthetic biologists is the ability to unambiguously describe novel designs such that they can be reengineered by a third-party. For this reason, the synthetic biology open language (SBOL) was developed as a community wide standard for formally representing biological designs. A design created by one engineering team can be transmitted electronically to another who can then use this design to reproduce the experimental results. The development and the community of the SBOL standard started in 2008 and has since grown in use with now over 80 participants, including international, academic, and industrial interests. SBOL has stimulated the development of repositories and software tools to help synthetic biologists in their design efforts. This chapter summarizes the latest developments and future of the SBOL standard and its supporting infrastructure.