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Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach

Lookup NU author(s): Dr Andrey Zaytsev, Dr Barry Dodd, Emeritus Professor Bernard Golding, Professor Roger Griffin, Dr Xiaohong Lu, Professor Herbie Newell, Professor John LunecORCiD, Dr Ian HardcastleORCiD



This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).

Publication metadata

Author(s): Zaytsev A, Dodd B, Magnani M, Ghiron C, Golding BT, Griffin RJ, Liu J, Lu X, Micco I, Newell DR, Padova A, Robertson G, Lunec J, Hardcastle IR

Publication type: Article

Publication status: Published

Journal: Chemical Biology and Drug Discovery

Year: 2015

Volume: 86

Issue: 2

Pages: 180-189

Print publication date: 01/08/2015

Online publication date: 19/12/2014

Acceptance date: 15/10/2014

Date deposited: 07/03/2016

ISSN (print): 1747-0277

ISSN (electronic): 1747-0285

Publisher: Wiley


DOI: 10.1111/cbdd.12474

PubMed id: 25388787


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Funder referenceFunder name
Cancer Research UK
LSHC-CT-2007-037834European Union FP6 (DePPICT)