Publications by Dr Xiaohong Lu - ePrints

Browsing publications by Dr Xiaohong Lu.

Newcastle Authors	Title	Year
Dr Catherine Drummond Arman Esfandiari Dr Xiaohong Lu Dr Claire Hutton Dr Jennifer Jackson et al.	TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation	2016
Dr Andrey Zaytsev Dr Barry Dodd Emeritus Professor Bernard Golding Professor Roger Griffin Dr Xiaohong Lu et al.	Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach	2015
Dr Tim Blackburn Christopher Coxon Dr Xiaohong Lu Emeritus Professor Bernard Golding Professor Roger Griffin et al.	Diaryl- and triaryl-pyrrole derivatives: inhibitors of the MDM2-p53 and MDMX-p53 protein-protein interactions	2013
Dr Ian Hardcastle Alex Liu Dr Eric Valeur Anna Watson Shafiq Ahmed et al.	Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein-Protein Interaction: Structure-Activity Studies Leading to Improved Potency	2011
Dr Ian Logan Hesta McNeill Susan Cook Dr Xiaohong Lu Professor John Lunec et al.	Heat shock factor-1 modulates p53 activity in the transcriptional response to DNA damage	2009
Dr Xiaohong Lu Professor John Lunec	Disruption of the MYC transcriptional function by a small-molecule antagonist of MYC/MAX dimerization	2008
Dr Ian Logan Hesta McNeill Susan Cook Dr Xiaohong Lu Professor John Lunec et al.	Analysis of the MDM2 antagonist nutlin-3 in human prostate cancer cells	2007
Dr Emma Bell Dr Jane Carr-Wilkinson Dr Xiaohong Lu Professor Penny Lovat Professor John Lunec et al.	The role of MYCN in the failure of MYCN amplified neuroblastoma cell lines to G1 arrest after DNA damage	2006
Dr Xiaohong Lu Professor Herbie Newell Professor Andrew Pearson Professor John Lunec	Identification of MYCN transcriptional activity inhibitors yields compounds which preferentially inhibit the growth of neuroblastoma cells	2004
Dr Xiaohong Lu Professor Andrew Pearson Professor John Lunec	The MYCN oncoprotein as a drug development target	2003
Dr Debbie Scott Julian Board Dr Xiaohong Lu Professor Andrew Pearson Dr Rebecca Kenyon et al.	The neuroblastoma amplified gene, NAG: Genomic structure and characterisation of the 7.3 kb transcript predominantly expressed in neuroblastoma	2003
Dr Xiaohong Lu Julie Errington Professor Nicola Curtin Professor Alan Boddy Professor Herbie Newell et al.	Cellular ATP depletion by LY309887 as a predictor of growth inhibition in human tumor cell lines	2000