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New Interview and Observation Measures of the Broader Autism Phenotype: Group Differentiation

Lookup NU author(s): Professor Jeremy Parr


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To identify the broader autism phenotype (BAP), the Family History Interview subject and informant versions and an observational tool (Impression of Interviewee), were developed. This study investigated whether the instruments differentiated between parents of children with autism, and parents of children with Down syndrome (DS). The BAP scores of parents of 28 multiplex autism families were compared with parents from, 32 DS families. The BAP measures provided good group differentiation but when considered together, the subject interview did not improve group differentiation. The differentiation was better for fathers than mothers. The measures do carry an important degree of validity; whether they can differentiate the BAP from other social disorders should be tested.

Publication metadata

Author(s): de Jonge M, Parr J, Rutter M, Wallace S, Kemner C, Bailey A, van Engeland H, Pickles A

Publication type: Article

Publication status: Published

Journal: Journal of Autism and Developmental Disorders

Year: 2015

Volume: 45

Issue: 4

Pages: 893-901

Print publication date: 01/04/2015

Online publication date: 23/09/2014

Acceptance date: 01/01/1900

ISSN (print): 0162-3257

ISSN (electronic): 1573-3432

Publisher: Springer


DOI: 10.1007/s10803-014-2230-7


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Funder referenceFunder name
Conseil Regional Midi-Pyrenees
Danish Medical Research Council
Deutsche Forschungsgemeinschaft
Fondation France Telecom
Fondazione Cassa di Risparmio di Bologna
Janusz Korczack Foundation
Medical Research Council
Beatrice Surovell Haskells Fond for Child Mental Health Research of Copenhagen
Wellcome Trust
9802210Danish Natural Science Research Council
CT-972759BIOMED 2
GR071470MANancy Lurie Marks Family Foundation
QLG2-CT-1999-0094EC Fifth Framework