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Facilitation of blood donation amongst haemochromatosis patients

Lookup NU author(s): Dr Steven MassonORCiD


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Background/Objective: The standard medical therapy for haemochromatosis is iron removal by regular phlebotomy. Current guidelines suggest that this blood should be made available through national blood services. Here, we describe a pilot facilitating the process of blood donation amongst uncomplicated haemochromatosis patients.Methods/Materials: At a dedicated clinic, patients with uncomplicated haemochromatosis interested in becoming blood donors were offered an information leaflet and self-referral application. Upon receipt, members of the local Blood Service contacted them to confirm eligibility to donate. Data on demographics and clinical characteristics, including HFE (high Fe) genotype, co-morbidities, alcohol consumption and body mass index, were collected.Results: Since establishing the clinic, 140 patients have attended (93 male) with median age 57. Most (n= 125; 89%) had uncomplicated haemochromatosis. Of these, 55 were potentially eligible blood donors. Amongst those eligible, there are now 29 regular blood donors, including 23 new.Conclusion: There is an interest and willingness to donate blood through the Blood Service amongst uncomplicated haemochromatosis patients undergoing therapeutic phlebotomy. Since the introduction of this facilitation process, we have significantly increased the number of regular donors amongst this cohort. If this process was to be replicated more widely across the UK, this could have a significant impact on the blood donor pool.

Publication metadata

Author(s): Marrow B, Clarkson J, Chapman CE, Masson S

Publication type: Article

Publication status: Published

Journal: Transfusion Medicine

Year: 2015

Volume: 25

Issue: 4

Pages: 239-242

Print publication date: 01/08/2015

Online publication date: 19/03/2015

Acceptance date: 23/02/2015

ISSN (print): 0958-7578

ISSN (electronic): 1365-3148

Publisher: Wiley-Blackwell


DOI: 10.1111/tme.12182


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