Browse by author
Lookup NU author(s): Professor Thomas Hill
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Context: Vitamin D insufficiency is common among the adolescent population and may have implications for health outcomes in later life. Few studies have investigated the role of vitamin D status in muscle function and cardiorespiratory fitness (CRF) during adolescence.Objective: The aim of this study was to investigate the association between vitamin D status and fat-free mass (FFM), muscle strength, muscle power, and CRF in a representative sample of adolescents from Northern Ireland.Design, Setting, and Participants: This was a cross-sectional study involving 1015 adolescents (age 12 and 15 y), who had 25-hydroxyvitamin D [25(OH) D] data available as part of the Young Hearts Study 2000.Main Outcome Measures: The main outcome measures of this study were FFM (kg) and FFM corrected for height [fat-free mass index; FFM (kg)/height (m(2))], muscle strength (kg), peak muscle power (kW) and VO2 max (CRF; mL/kg/min).Results: Multinomial regression analyses, controlling for environmental and lifestyle factors, demonstrated that boys age 15 years in the highest tertile of standardized serum 25(OH) D concentration (> 51 nmol/L) hadsignificantly higher muscle strength (beta = 3.90; P <= .001) compared with those in the lowest tertile (< 32 nmol/L). These results were not evident in any other age-sex group and vitamin D status was not significantly associated with muscle power or CRF in any of the four age-sex groups.Conclusion: These results support a role for vitamin D in muscle function in adolescent males and suggest the need for more research in this vulnerable age group.
Author(s): Carson EL, Pourshahidi LK, Hill TR, Cashman KD, Strain JJ, Boreham CA, Mulhern MS
Publication type: Article
Publication status: Published
Journal: Journal of Clinical Endocrinology & Metabolism
Print publication date: 01/12/2015
Online publication date: 20/10/2015
Acceptance date: 15/10/2015
ISSN (print): 0021-972X
ISSN (electronic): 1945-7197
Publisher: The Endocrine Society
Altmetrics provided by Altmetric