ePrints

Investigation of human chromosome polymorphisms by scanning electron microscopy

Lookup NU author(s): Professor Christine Harrison FRCPath FMedSci

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.

Abstract

Human chromosome polymorphisms were investigated by scanning electron microscopy (SEM). Centromeric heterochromatin was of a constricted morphology. The extent of the C banded region was demarcated by a prominent circumferential groove in G banded chromosomes. Circumferential grooves were observed within the heterochromatin of chromosome 9, and the number of grooves present reflected the size of the region. Three dimensional viewing of satellites and short arms of acrocentric chromosomes, from different angles in the SEM, provided the opportunity for accurate assessment of the size of satellites to be made. Also, small morphological variations were defined in the SEM when definition was uncertain in the light microscope (LM).

Publication metadata

Author(s): Harrison CJ, Jack EM, Allen TD, Harris R

Publication type: Article

Publication status: Published

Journal: Journal of Medical Genetics

Year: 1985

Volume: 22

Issue: 1

Pages: 16-23

Print publication date: 01/02/1985

ISSN (print): 0022-2593

ISSN (electronic): 1468-6244

Publisher: BMJ Group

URL: http://dx.doi.org/10.1136/jmg.22.1.16

DOI: 10.1136/jmg.22.1.16

Notes: Journal Article Research Support, Non-U.S. Gov't England

Altmetrics

Share