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Sleep problems in bipolar disorders: more than just insomnia

Lookup NU author(s): Emeritus Professor Jan Scott

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Abstract

ObjectiveSleep problems in bipolar disorder (BD) are common, but reported rates vary from 10% to 80%, depending on definitions, methodologies and management of potential confounding factors. This multicenter study seeks to address these issues and also compares BD cases with Hypersomnia as well as the more commonly investigated Insomnia and No Sleep Problem groups.MethodA cross-sectional comparison of sleep profiles in 563 BD I and II individuals who participated in a structured assessment of demographic, clinical, illness history and treatment variables.ResultsOver 40% cases met criteria for Insomnia and 29% for Hypersomnia. In univariate analysis, Insomnia was associated with BD II depression whilst Hypersomnia was associated with BD I depression or euthymia. After controlling for confounders and covariates, it was demonstrated that Hypersomnia cases were significantly more likely to be younger, have BD I and be prescribed antidepressants whilst Insomnia cases had longer illness durations and were more likely to be prescribed benzodiazepines and hypnotics.ConclusionWhilst Insomnia symptoms are common in BD, Hypersomnia is a significant, frequently underexplored problem. Detailed analyses of large representative clinical samples are critical to extending our knowledge of differences between subgroups defined by sleep profile.

Publication metadata

Author(s): Steinan MK, Scott J, Lagerberg TV, Melle I, Andreassen OA, Vaaler AE, Morken G

Publication type: Article

Publication status: Published

Journal: Acta Psychiatrica Scandinavica

Year: 2016

Volume: 133

Issue: 5

Pages: 368-377

Print publication date: 01/05/2016

Online publication date: 21/11/2015

Acceptance date: 08/10/2015

Date deposited: 07/06/2016

ISSN (print): 0001-690X

ISSN (electronic): 1600-0447

Publisher: Wiley-Blackwell

URL: http://dx.doi.org/10.1111/acps.12523

DOI: 10.1111/acps.12523

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