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Combined PI3K and CDK2 inhibition induces cell death and enhances in vivo anti-tumour activity in colorectal cancer

Lookup NU author(s): Dr Gary Beale, Dr Emma Haagensen, Huw ThomasORCiD, Lan Wang, Charlotte Revill, Sara Payne, Emeritus Professor Bernard Golding, Dr Ian HardcastleORCiD, Professor Herbie Newell, Professor Roger Griffin, Dr Celine CanoORCiD

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This is the authors' accepted manuscript of an article that has been published in its final definitive form by Nature Publishing Group, 2016.

For re-use rights please refer to the publisher's terms and conditions.


Publication metadata

Author(s): Beale G, Haagensen E, Thomas H, Wang LZ, Revill C, Payne S, Golding BT, Hardcastle IR, Newell DR, Griffin RJ, Cano C

Publication type: Article

Publication status: Published

Journal: British Journal of Cancer

Year: 2016

Volume: 115

Pages: 682-690

Print publication date: 06/09/2016

Online publication date: 16/08/2016

Acceptance date: 14/07/2016

Date deposited: 19/08/2016

ISSN (print): 0007-0920

ISSN (electronic): 1532-1827

Publisher: Nature Publishing Group

URL: http://dx.doi.org/10.1038/bjc.2016.238

DOI: 10.1038/bjc.2016.238


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Funding

Funder referenceFunder name
UCB Celltech
C240/A7409CR UK Drug Discovery Programme
C240/A7409CR UK Drug Discovery Programme
C240/A7409CR UK Drug Discovery Programme
C240/A7409CR UK Drug Discovery Programme
C129/A6963CR UK Medicinal Chemistry Training Programme
C8120/A8000CR UK

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