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Diagnosis and Management of Patients with primary biliary cirrchosis

Lookup NU author(s): Dr Jess Dyson, Professor David Jones


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rimary biliary cirrhosis (PBC) is now most frequently diagnosed as a result of an assessment following the identification of abnormal liver biochemistry in an otherwise well patient. An increasing number of patients are diagnosed after investigations of unexplained fatigue. Cholestatic pruritus can be a presenting feature in some, and occasional patients will present with end-stage liver disease. Improvements in the range and effectiveness of therapies over the next few years are likely to increase the importance of an early diagnosis for optimal therapy.

Publication metadata

Author(s): Dyson JK, Jones DEJ

Publication type: Article

Publication status: Published

Journal: Clinical Liver Disease

Year: 2014

Volume: 3

Issue: 3

Pages: 43-68

Print publication date: 01/04/2014

Online publication date: 01/04/2014

Acceptance date: 01/03/2014

ISSN (electronic): 2046-2484

Publisher: Wiley-Blackwell Publishing Ltd.


DOI: 10.1002/cld.320


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