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Lookup NU author(s): Professor Christine Harrison FRCPath FMedSci
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Bone marrow cells from patients with chronic myeloid leukemia (CML) in in vitro long-term bone marrow culture (LTBMC) show an impaired survival of Philadelphia (Ph) positive cells and, in a proportion of patients, the emergence of Philadelphia negative hemopoiesis. The standard conditions of in vitro cultures provide optimal purging effect. Selected patients can now have autologous bone marrow transplants (ABMT) with in vitro purged cells.
Author(s): Chang J, Coutinho LH, Santos AMW, Brereton M, Harrison CJ, Testa NG
Publication type: Article
Publication status: Published
Journal: Stem Cells
Issue: Suppl 1
Print publication date: 01/05/1993
ISSN (print): 1066-5099
ISSN (electronic): 1549-4918
Publisher: AlphaMed Press, Inc.
Notes: Journal Article
Research Support, Non-U.S. Gov't
Supplementary Issue: Proceedings of the Conference Celebrating the 40th Anniversary of the Institute of Hematology and Blood Transfusion
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