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Lookup NU author(s): Professor Christine Harrison FRCPath FMedSci
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We report a case of disseminated alveolar rhabdomyosarcoma, where chromosome analysis showed a deletion of chromosome 13(q14). This breakpoint is involved in the t(2;13)(q37;q14) previously reported in cases of rhabdomyosarcoma, but this is the first reported case in whom this deletion occurs without involvement of chromosome 2. The possible oncogenic role of the retinoblastoma (RB1) gene located at the breakpoint is discussed.
Author(s): Harrison CJ, Johnson PR, Yin JA, Bhavnani M
Publication type: Article
Publication status: Published
Journal: Cancer Genetics and Cytogenetics
Print publication date: 01/09/1991
ISSN (print): 0165-4608
ISSN (electronic): 1873-4456
Notes: Case Reports
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