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Dormancy Stems the Tide of Chemotherapy

Lookup NU author(s): Dr Deepali Pal, Professor Olaf Heidenreich, Professor Hermann Josef Vormoor


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In this issue of Cancer Cell, Ebinger et al. describe rare, non-cycling blasts in acute lymphoblastic leukemia that combine the phenotypes of dormancy, sternness, and chemo-resistance. This novel in vivo model for dormant blasts will facilitate the dissection of the niche and the development of therapies targeting the leukemic microenvironment.

Publication metadata

Author(s): Pal D, Heidenreich O, Vormoor J

Publication type: Editorial

Publication status: Published

Journal: Cancer Cell

Year: 2016

Volume: 30

Issue: 6

Pages: 825-826

Print publication date: 12/12/2016

Online publication date: 12/12/2016

Acceptance date: 28/11/2016

ISSN (print): 1535-6108

ISSN (electronic): 1878-3686

Publisher: Cell Press


DOI: 10.1016/j.ccell.2016.11.014