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Monocytoid B cell lymphoma

Lookup NU author(s): Professor Christine Harrison FRCPath FMedSci


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The clinical, light microscopic, ultrastructural, immunocytochemical and cytogenetic features of a case of monocytoid B cell lymphoma were investigated. The tumour initially affected the cervical and supraclavicular nodes, but 33 months later affected the left parotid salivary gland. The patient had subclinical Sjogren's syndrome. The neoplastic cells showed characteristic morphological features and had peri- and interfollicular distribution in the node. Immunocytochemically the tumour cells were L26, 4KB5, MB2, CD19, CD20, CD22 and IgM/kappa positive. Prominent plasmablastic plasmacytoid differentiation was present in the recurrent tumour, suggesting an origin from post-follicular B cells. The lymphoma cells showed unusual cytogenetic abnormalities.

Publication metadata

Author(s): Banerjee SS, Harris M, Eyden BP, Radford JA, Harrison CJ, Mainwaring AR

Publication type: Article

Publication status: Published

Journal: Journal of Clinical Pathology

Year: 1991

Volume: 44

Issue: 1

Pages: 39-44

Print publication date: 01/01/1991

ISSN (print): 0021-9746

ISSN (electronic): 1472-4146

Publisher: BMJ Group


DOI: 10.1136/jcp.44.1.39

Notes: Case Reports Journal Article England


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