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Lookup NU author(s): Professor Christine Harrison FRCPath FMedSci
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The clinical, light microscopic, ultrastructural, immunocytochemical and cytogenetic features of a case of monocytoid B cell lymphoma were investigated. The tumour initially affected the cervical and supraclavicular nodes, but 33 months later affected the left parotid salivary gland. The patient had subclinical Sjogren's syndrome. The neoplastic cells showed characteristic morphological features and had peri- and interfollicular distribution in the node. Immunocytochemically the tumour cells were L26, 4KB5, MB2, CD19, CD20, CD22 and IgM/kappa positive. Prominent plasmablastic plasmacytoid differentiation was present in the recurrent tumour, suggesting an origin from post-follicular B cells. The lymphoma cells showed unusual cytogenetic abnormalities.
Author(s): Banerjee SS, Harris M, Eyden BP, Radford JA, Harrison CJ, Mainwaring AR
Publication type: Article
Publication status: Published
Journal: Journal of Clinical Pathology
Year: 1991
Volume: 44
Issue: 1
Pages: 39-44
Print publication date: 01/01/1991
ISSN (print): 0021-9746
ISSN (electronic): 1472-4146
Publisher: BMJ Group
URL: http://dx.doi.org/10.1136/jcp.44.1.39
DOI: 10.1136/jcp.44.1.39
Notes: Case Reports Journal Article England
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