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Normal and abnormal development of the heart

Lookup NU author(s): Professor Bob Anderson, Dr Simon BamforthORCiD, Dr Bill Chaudhry, Professor Deborah HendersonORCiD


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© Springer-Verlag London 2014.Accurate knowledge of embryology is essential for interpretation of congenital cardiac malformations. Recent advances made in the understanding of cardiac development now make it possible to appreciate the morphology of not only the normal heart but also many congenital cardiac malformations. This is true not only for the molecular mechanisms that might lead to the malformations but also for the structure of the normal and abnormally developing heart. In this chapter, we discuss the progress made in demonstrating the structure of the developing heart, along with knowledge of the changes that occur in the expression of the genes and their products, which control the formation and differentiation of its various components.

Publication metadata

Author(s): Anderson RH, Moorman AFM, Brown NA, Bamforth SD, Chaudhry B, Henderson DJ, Mohun TJ

Publication type: Book Chapter

Publication status: Published

Book Title: Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care

Year: 2014

Pages: 151-177

Print publication date: 01/01/2014

Online publication date: 18/09/2013

Acceptance date: 01/01/1900

Publisher: Springer-Verlag

Place Published: London


DOI: 10.1007/978-1-4471-4619-3_153

Library holdings: Search Newcastle University Library for this item

ISBN: 9781447146193