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Lookup NU author(s): Dr Vicky Brocklebank,
Professor David Kavanagh
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© 2014 Royal College of Physicians. Atypical haemolytic uraemic syndrome is a thrombotic microangiopathy with a predominant renal phenotype. Research developments in the last 15 years have led to the elucidation of the role of complement over activation in the pathogenesis of the disease. This was to lead to the successful introduction of targeted pharmacological therapy, in the form of the complement inhibitor, eculizumab.
Author(s): Brocklebank V, Kavanagh D
Publication type: Review
Publication status: Published
Journal: Clinical Medicine
Issue: suppl. 6
Print publication date: 01/12/2014
Acceptance date: 01/01/1900
ISSN (print): 1473-4893
PubMed id: 25468928