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Lookup NU author(s): Professor Bob Anderson
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© Springer-Verlag Wien 2016. The seeming simplicity of the clinical presentation and management of an atrial septal defect belies the complexity of the developmental pathogenesis. Here, we describe the anatomic development of the atrial septum and the venous return to the atrial chambers. Recent experimental results suggest where genetic mutations could disrupt developmental steps to cause a defect within the oval fossa, the so-called secundum defect or other interatrial communication, such as the sinus venosus defect.
Author(s): Jay PY, Degenhardt KR, Anderson RH
Publication type: Book Chapter
Publication status: Published
Book Title: Congenital Heart Diseases: The Broken Heart: Clinical Features, Human Genetics and Molecular Pathways
Year: 2015
Pages: 291-300
Print publication date: 18/12/2015
Acceptance date: 01/01/1900
Publisher: Springer-Verlag Wien
URL: http://doi.org/10.1007/978-3-7091-1883-2_21
DOI: 10.1007/978-3-7091-1883-2_21
Library holdings: Search Newcastle University Library for this item
ISBN: 9783709118832
